Literature DB >> 31844977

Scientific solution to a complex problem: physiology and multidisciplinary team improve understanding and outcome in chronic constipation and faecal incontinence.

Eleni Athanasakos1, Sally Dalton2, Susan McDowell2, Tara Shea2, Kate Blakeley2, David Rawat2, Stewart Cleeve2.   

Abstract

PURPOSE: There is a lack of diagnostic credibility to direct focused management for children with chronic constipation (CC) and faecal incontinence (FI). The aim is to assess the impact of an innovative Children's Anorectal Physiology Service (CAPS) focusing on improving outcomes in children with CC/FI.
METHODS: Prospective data: demographics, bowel and quality of life (QoL)/risk of distress questionnaires. Diagnostics: awake high-resolution anorectal manometry (AHRAM), endoanal ultrasound and transit marker studies (TMS).
RESULTS: Total patients: 112; 66 males (59%); median 9 years (17 months to 16 years). Patient groups included: 89 (79%) had functional CC/FI; 9 (8%), Hirschsprung's disease; 12 (11%), anorectal malformations and 2 (2%), trauma. St Marks Incontinence score (SMIS) abnormal in 91 (81%) and Cleveland Constipation Score (CCS) in 101 (90%) patients. Anorectal manometry: 94 (84%) awake and 18 (17%) under anaesthesia. Play specialist input 37 (33%) patients. AHRAM abnormal 65 (58%): sphincter dysfunction 36 (32%) and altered rectal sensation: hyposensitive 22% (20/91); 21% (19/91) hypersensitive. TMS normal in 64 (57%), 17 (15%) slow transit and 27 (24%) rectal evacuatory disorder. Risk of distress in 38% and poor QoL in 55% patients which correlated with abnormal SMIS (p = 0.02). Patient/parent satisfaction improved significantly (p < 0.05).
CONCLUSIONS: Scientific investigations combined with multidisciplinary team improve patient satisfaction and reduces patient self-report illness severity. A complex problem requires a scientific solution.

Entities:  

Keywords:  Anorectal physiology; Chronic constipation; Faecal incontinence; High-resolution anorectal manometry (HRAM); Multidisciplinary team (MDT); Pathophysiology

Mesh:

Year:  2019        PMID: 31844977     DOI: 10.1007/s00383-019-04605-y

Source DB:  PubMed          Journal:  Pediatr Surg Int        ISSN: 0179-0358            Impact factor:   1.827


  65 in total

1.  Rectal hyposensitivity: prevalence and clinical impact in patients with intractable constipation and fecal incontinence.

Authors:  Marc A Gladman; S Mark Scott; Christopher L H Chan; Norman S Williams; Peter J Lunniss
Journal:  Dis Colon Rectum       Date:  2003-02       Impact factor: 4.585

2.  Constipation in children: novel insight into epidemiology, pathophysiology and management.

Authors:  Shaman Rajindrajith; Niranga Manjuri Devanarayana
Journal:  J Neurogastroenterol Motil       Date:  2011-01-26       Impact factor: 4.924

Review 3.  Rectal sensorimotor dysfunction in constipation.

Authors:  S M Scott; M M van den Berg; M A Benninga
Journal:  Best Pract Res Clin Gastroenterol       Date:  2011-02       Impact factor: 3.043

4.  Anorectal manometry with reference to operative rectal biopsy for the diagnosis/exclusion of Hirschprung's disease in children under 1 year of age.

Authors:  Kristiina Jarvi; Antti Koivusalo; Risto J Rintala; Mikko P Pakarinen
Journal:  Int J Colorectal Dis       Date:  2008-12-16       Impact factor: 2.571

5.  Effect of sacral magnetic stimulation on the anorectal manometric activity: a new modality for examining sacro-rectoanal interaction.

Authors:  Masayuki Kubota; Naoki Okuyama; Yutaka Hirayama; Kumiko Kobayashi; Kanako Satoh
Journal:  Pediatr Surg Int       Date:  2007-06-14       Impact factor: 1.827

6.  Evaluation of outcome of anorectal anomaly in childhood: the role of anorectal manometry and endosonography.

Authors:  A S Keshtgar; E Athanasakos; G S Clayden; H C Ward
Journal:  Pediatr Surg Int       Date:  2008-05-30       Impact factor: 1.827

7.  Evaluation of postoperative anal functions using endoanal ultrasonography and anorectal manometry in children with congenital anorectal malformations.

Authors:  Zhichao Wang; Lijun Hu; Xianqing Jin; Xiaoqing Li; Lixia Xu
Journal:  J Pediatr Surg       Date:  2015-11-10       Impact factor: 2.545

8.  Traditional measures of normal anal sphincter function using high-resolution anorectal manometry (HRAM) in 115 healthy volunteers.

Authors:  E V Carrington; A Brokjaer; H Craven; N Zarate; E J Horrocks; S Palit; W Jackson; G S Duthie; C H Knowles; P J Lunniss; S M Scott
Journal:  Neurogastroenterol Motil       Date:  2014-03-13       Impact factor: 3.598

9.  The PedsQL 4.0 as a pediatric population health measure: feasibility, reliability, and validity.

Authors:  James W Varni; Tasha M Burwinkle; Michael Seid; Douglas Skarr
Journal:  Ambul Pediatr       Date:  2003 Nov-Dec

10.  Rectal hyposensitivity.

Authors:  Rebecca E Burgell; S Mark Scott
Journal:  J Neurogastroenterol Motil       Date:  2012-10-09       Impact factor: 4.924

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