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Literature DB >> 31844841

MicroRNA regulation of CD8⁺ T cell responses.

Abstract

MicroRNAs (miRNAs) are a class of short noncoding RNAs that play critical roles in the regulation of a broad range of biological processes. Like transcription factors, miRNAs exert their effects by modulating the expression of networks of genes that operate in common or convergent pathways. CD8+ T cells are critical agents of the adaptive immune system that provide protection from infection and cancer. Here, we review the important roles of miRNAs in the regulation of CD8+ T cell biology and provide perspectives on the broader emerging principles of miRNA function.

Entities: Chemical Disease Gene Species

Keywords: MicroRNA (miRNA); T cell exhaustion; T cell memory; cytotoxic T cell

Year: 2019 PMID： 31844841 PMCID： PMC6913524 DOI： 10.21037/ncri.2019.07.02

Source DB: PubMed Journal: Noncoding RNA Investig ISSN： 2522-6673

107 in total

1. KLRG1⁺ Effector CD8⁺ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity.

Authors: Dietmar Herndler-Brandstetter; Harumichi Ishigame; Ryo Shinnakasu; Valerie Plajer; Carmen Stecher; Jun Zhao; Melanie Lietzenmayer; Lina Kroehling; Akiko Takumi; Kohei Kometani; Takeshi Inoue; Yuval Kluger; Susan M Kaech; Tomohiro Kurosaki; Takaharu Okada; Richard A Flavell
Journal: Immunity Date: 2018-04-03 Impact factor: 31.745

2. miR-15 and miR-16 induce apoptosis by targeting BCL2.

Authors: Amelia Cimmino; George Adrian Calin; Muller Fabbri; Marilena V Iorio; Manuela Ferracin; Masayoshi Shimizu; Sylwia E Wojcik; Rami I Aqeilan; Simona Zupo; Mariella Dono; Laura Rassenti; Hansjuerg Alder; Stefano Volinia; Chang-Gong Liu; Thomas J Kipps; Massimo Negrini; Carlo M Croce
Journal: Proc Natl Acad Sci U S A Date: 2005-09-15 Impact factor: 11.205

3. Restoring function in exhausted CD8 T cells during chronic viral infection.

Authors: Daniel L Barber; E John Wherry; David Masopust; Baogong Zhu; James P Allison; Arlene H Sharpe; Gordon J Freeman; Rafi Ahmed
Journal: Nature Date: 2005-12-28 Impact factor: 49.962

4. Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells.

Authors: Christopher A Klebanoff; Luca Gattinoni; Parizad Torabi-Parizi; Keith Kerstann; Adela R Cardones; Steven E Finkelstein; Douglas C Palmer; Paul A Antony; Sam T Hwang; Steven A Rosenberg; Thomas A Waldmann; Nicholas P Restifo
Journal: Proc Natl Acad Sci U S A Date: 2005-06-24 Impact factor: 11.205

5. miR-150-Mediated Foxo1 Regulation Programs CD8⁺ T Cell Differentiation.

Authors: Young Ho Ban; Se-Chan Oh; Sang-Hwan Seo; Seok-Min Kim; In-Pyo Choi; Philip D Greenberg; Jun Chang; Tae-Don Kim; Sang-Jun Ha
Journal: Cell Rep Date: 2017-09-12 Impact factor: 9.423

Review 6. Regulation of miRNA biogenesis and turnover in the immune system.

Authors: Yelena Bronevetsky; K Mark Ansel
Journal: Immunol Rev Date: 2013-05 Impact factor: 12.988

7. Expression of IL-7 receptor alpha is necessary but not sufficient for the formation of memory CD8 T cells during viral infection.

Authors: Timothy W Hand; Michel Morre; Susan M Kaech
Journal: Proc Natl Acad Sci U S A Date: 2007-07-03 Impact factor: 11.205

8. miR-143 Regulates Memory T Cell Differentiation by Reprogramming T Cell Metabolism.

Authors: Tengfei Zhang; Zhen Zhang; Feng Li; Yu Ping; Guohui Qin; Chaoqi Zhang; Yi Zhang
Journal: J Immunol Date: 2018-08-27 Impact factor: 5.422

Review 9. CD8(+) T cells: foot soldiers of the immune system.

Authors: Nu Zhang; Michael J Bevan
Journal: Immunity Date: 2011-08-26 Impact factor: 31.745

10. T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire.

Authors: Yelena Bronevetsky; Alejandro V Villarino; Christopher J Eisley; Rebecca Barbeau; Andrea J Barczak; Gitta A Heinz; Elisabeth Kremmer; Vigo Heissmeyer; Michael T McManus; David J Erle; Anjana Rao; K Mark Ansel
Journal: J Exp Med Date: 2013-02-04 Impact factor: 14.307

7 in total

MicroRNA regulation of CD8⁺ T cell responses.

1. KLRG1⁺ Effector CD8⁺ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity.

2. miR-15 and miR-16 induce apoptosis by targeting BCL2.

3. Restoring function in exhausted CD8 T cells during chronic viral infection.

4. Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells.

5. miR-150-Mediated Foxo1 Regulation Programs CD8⁺ T Cell Differentiation.

Review 6. Regulation of miRNA biogenesis and turnover in the immune system.

7. Expression of IL-7 receptor alpha is necessary but not sufficient for the formation of memory CD8 T cells during viral infection.

8. miR-143 Regulates Memory T Cell Differentiation by Reprogramming T Cell Metabolism.

Review 9. CD8(+) T cells: foot soldiers of the immune system.

10. T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire.

Review 1. Sequence determinants as key regulators in gene expression of T cells.

Review 2. Non-coding RNAs in CD8 T cell biology.

3. Bortezomib Sustains T Cell Function by Inducing miR-155-Mediated Downregulation of SOCS1 and SHIP1.

4. RNA-Binding Protein Expression Alters Upon Differentiation of Human B Cells and T Cells.

5. MicroRNA-mediated metabolic reprogramming of chimeric antigen receptor T cells.

6. The DCMU Herbicide Shapes T-cell Functions By Modulating Micro-RNA Expression Profiles.

Review 7. A key control point in the T cell response to chronic infection and neoplasia: FOXO1.