Marie-Eve Robinson1,2,3, Marc Simard4, Isabelle Larocque4, Jai Shah5,6, Meranda Nakhla3,7, Elham Rahme8,9. 1. Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada. 2. Division of Endocrinology, Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada. 3. Division of Endocrinology, Department of Pediatrics, McGill University Health Centre, Montreal, Quebec, Canada. 4. Institut National de Santé Publique du Québec, Quebec City, Quebec, Canada. 5. Douglas Mental Health University Institute, McGill University, Montreal, Quebec, Canada. 6. Department of Psychiatry, McGill University, Montreal, Quebec, Canada. 7. Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada. 8. Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada elham.rahme@mcgill.ca. 9. Division of Clinical Epidemiology, Department of Medicine, McGill University, Montreal, Quebec, Canada.
Abstract
OBJECTIVE: To determine the longitudinal risks of psychiatric disorders in adolescents and emerging adults with versus without diabetes. RESEARCH DESIGN AND METHODS: We conducted a retrospective cohort study in Quebec, Canada, using linked health administrative databases of adolescents (age 15 years) with and without diabetes and without prior psychiatric disorders between 1997 and 2015, followed to age 25 years. RESULTS: Our cohort included 3,544 individuals with diabetes and 1,388,397 without diabetes. Individuals with diabetes were more likely to suffer from a mood disorder (diagnosed in the emergency department or hospital) (adjusted hazard ratio 1.33 [95% CI 1.19-1.50]), attempt suicide (3.25 [1.79-5.88]), visit a psychiatrist (1.82 [1.67-1.98]), and experience any type of psychiatric disorder (1.29 [1.21-1.37]) compared with their peers without diabetes. CONCLUSIONS: Between the ages of 15 and 25 years, the risks of psychiatric disorders and suicide attempts were substantially higher in adolescents and emerging adults with versus without diabetes.
OBJECTIVE: To determine the longitudinal risks of psychiatric disorders in adolescents and emerging adults with versus without diabetes. RESEARCH DESIGN AND METHODS: We conducted a retrospective cohort study in Quebec, Canada, using linked health administrative databases of adolescents (age 15 years) with and without diabetes and without prior psychiatric disorders between 1997 and 2015, followed to age 25 years. RESULTS: Our cohort included 3,544 individuals with diabetes and 1,388,397 without diabetes. Individuals with diabetes were more likely to suffer from a mood disorder (diagnosed in the emergency department or hospital) (adjusted hazard ratio 1.33 [95% CI 1.19-1.50]), attempt suicide (3.25 [1.79-5.88]), visit a psychiatrist (1.82 [1.67-1.98]), and experience any type of psychiatric disorder (1.29 [1.21-1.37]) compared with their peers without diabetes. CONCLUSIONS: Between the ages of 15 and 25 years, the risks of psychiatric disorders and suicide attempts were substantially higher in adolescents and emerging adults with versus without diabetes.
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