Whitney L Gervelis1, Meredith R Golomb2. 1. Division of Child Neurology, Department of Neurology, Riley Hospital for Children at Indiana University Health and Indiana University School of Medicine, Indianapolis, Indiana. 2. Division of Child Neurology, Department of Neurology, Riley Hospital for Children at Indiana University Health and Indiana University School of Medicine, Indianapolis, Indiana. Electronic address: mgolomb@iupui.edu.
Abstract
BACKGROUND: Mechanical thrombectomy for treatment of arterial ischemic stroke (AIS) and cerebral venous thrombosis (CVT) is well-studied in adult populations, but not in children. METHODS: We report 3 new cases of pediatric stroke treated using mechanical thrombectomy. Two cases of AIS and 1 case of CVT were identified from 2018 pediatric stroke clinic records. RESULTS: Thrombectomy was successful in 1 of the 2 AIS cases and in the CVT case. None of the children were asymptomatic after thrombectomy. One AIS case had good recovery than developed dystonia which responded to treatment; the second AIS case had residual hemiplegia; and the child with CVT had mild school problems. CONCLUSIONS: Mechanical thrombectomy is being increasingly used for pediatric stroke treatment. This study and recent literature reviews suggest thrombectomy holds promise as a treatment for selected pediatric stroke patients. Questions remain about the safety and efficacy of thrombectomy in children with stroke since large randomized controlled studies are not yet feasible.
BACKGROUND: Mechanical thrombectomy for treatment of arterial ischemic stroke (AIS) and cerebral venous thrombosis (CVT) is well-studied in adult populations, but not in children. METHODS: We report 3 new cases of pediatric stroke treated using mechanical thrombectomy. Two cases of AIS and 1 case of CVT were identified from 2018 pediatric stroke clinic records. RESULTS: Thrombectomy was successful in 1 of the 2 AIS cases and in the CVT case. None of the children were asymptomatic after thrombectomy. One AIS case had good recovery than developed dystonia which responded to treatment; the second AIS case had residual hemiplegia; and the child with CVT had mild school problems. CONCLUSIONS: Mechanical thrombectomy is being increasingly used for pediatric stroke treatment. This study and recent literature reviews suggest thrombectomy holds promise as a treatment for selected pediatric strokepatients. Questions remain about the safety and efficacy of thrombectomy in children with stroke since large randomized controlled studies are not yet feasible.
Authors: Peter B Sporns; Marios-Nikos Psychogios; Ronald Straeter; Uta Hanning; Jens Minnerup; René Chapot; Hans Henkes; Elina Henkes; Astrid Grams; Franziska Dorn; Omid Nikoubashman; Martin Wiesmann; Georg Bier; Anushe Weber; Gabriel Broocks; Jens Fiehler; Alex Brehm; Daniel Kaiser; Umut Yilmaz; Andrea Morotti; Wolfgang Marik; Richard Nolz; Ulf Jensen-Kondering; Michael Braun; Stefan Schob; Oliver Beuing; Friedrich Goetz; Johannes Trenkler; Bernd Turowski; Markus Möhlenbruch; Christina Wendl; Peter Schramm; Patricia L Musolino; Sarah Lee; Marc Schlamann; Alexander Radbruch; André Karch; Nicole Rübsamen; Moritz Wildgruber; André Kemmling Journal: Neurology Date: 2020-11-03 Impact factor: 9.910