Literature DB >> 31840184

Factors Associated With Antiretroviral Therapy Reinitiation in Medicaid Recipients With Human Immunodeficiency Virus.

T Zhang1, I B Wilson1, B Youn1, Y Lee1, T I Shireman1.   

Abstract

BACKGROUND: This study was conducted to examine patient characteristics associated with antiretroviral therapy (ART) reinitiation in Medicaid enrollees.
METHODS: This is a retrospective cohort study that uses Cox proportional hazard regression to examine the association between person-level characteristics and time from ART discontinuation to the subsequent reinitiation within 18 months.
RESULTS: There were 45 409 patients who discontinued ART, and 44% failed to reinitiate. More outpatient visits (3+ vs 0 outpatient visits: adjusted hazard ratio (adjHR), 1.56; 99% confidence interval [CI], 1.45-1.67) and hospitalization (adjHR, 1.18; 99% CI,1.16-1.20) during follow-up were associated with reinitiation.
CONCLUSIONS: Failure to reinitiate ART within 18 months was common in this sample. Care engagement was associated with greater ART reinitiation.
© The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  HIV; antiretroviral therapy; care engagement; reinitiation

Mesh:

Substances:

Year:  2020        PMID: 31840184      PMCID: PMC7184904          DOI: 10.1093/infdis/jiz666

Source DB:  PubMed          Journal:  J Infect Dis        ISSN: 0022-1899            Impact factor:   5.226


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