Literature DB >> 3183631

The A and B subgroups of human respiratory syncytial virus: comparison of intergenic and gene-overlap sequences.

P R Johnson1, P L Collins.   

Abstract

Intergenic and flanking gene regions for the 1C-1B, 1B-N, N-P, M-1A, G-F and F-22K gene junctions of respiratory syncytial virus strain 18537, representing antigenic subgroup B, were determined by dideoxynucleotide sequencing of polycistronic cDNAs and mRNAs. Comparison with their counterparts from the subgroup A strain A2 showed that the intergenic sequences were not conserved within or between the strains. Flanking non-coding gene sequences also were generally not conserved except for the highly conserved gene-start and gene-end transcription signals. The sequence of the overlap between the 22K and L genes was conserved almost exactly between the two subgroups.

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Year:  1988        PMID： 3183631     DOI： 10.1099/0022-1317-69-11-2901

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  12 in total

1.  Physical map of the genome of sonchus yellow net virus, a plant rhabdovirus with six genes and conserved gene junction sequences.

Authors:  L A Heaton; B I Hillman; B G Hunter; D Zuidema; A O Jackson
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

2.  Genetic diversity of the attachment protein of subgroup B respiratory syncytial viruses.

Authors:  W M Sullender; M A Mufson; L J Anderson; G W Wertz
Journal:  J Virol       Date:  1991-10       Impact factor: 5.103

3.  The structurally diverse intergenic regions of respiratory syncytial virus do not modulate sequential transcription by a dicistronic minigenome.

Authors:  L Kuo; R Fearns; P L Collins
Journal:  J Virol       Date:  1996-09       Impact factor: 5.103

4.  Analysis of the gene start and gene end signals of human respiratory syncytial virus: quasi-templated initiation at position 1 of the encoded mRNA.

Authors:  L Kuo; R Fearns; P L Collins
Journal:  J Virol       Date:  1997-07       Impact factor: 5.103

5.  Recombinant respiratory syncytial virus from which the entire SH gene has been deleted grows efficiently in cell culture and exhibits site-specific attenuation in the respiratory tract of the mouse.

Authors:  A Bukreyev; S S Whitehead; B R Murphy; P L Collins
Journal:  J Virol       Date:  1997-12       Impact factor: 5.103

6.  Production of infectious human respiratory syncytial virus from cloned cDNA confirms an essential role for the transcription elongation factor from the 5' proximal open reading frame of the M2 mRNA in gene expression and provides a capability for vaccine development.

Authors:  P L Collins; M G Hill; E Camargo; H Grosfeld; R M Chanock; B R Murphy
Journal:  Proc Natl Acad Sci U S A       Date:  1995-12-05       Impact factor: 11.205

7.  RNA sequences involved in transcriptional termination of respiratory syncytial virus.

Authors:  S B Harmon; A G Megaw; G W Wertz
Journal:  J Virol       Date:  2001-01       Impact factor: 5.103

8.  Detection of human respiratory syncytial virus in respiratory samples by LightCycler reverse transcriptase PCR.

Authors:  David M Whiley; Melanie W Syrmis; Ian M Mackay; Theo P Sloots
Journal:  J Clin Microbiol       Date:  2002-12       Impact factor: 5.948

9.  Analysis of respiratory syncytial virus genetic variability with amplified cDNAs.

Authors:  W M Sullender; L Sun; L J Anderson
Journal:  J Clin Microbiol       Date:  1993-05       Impact factor: 5.948

10.  Synthetic oligonucleotide probes differentiate respiratory syncytial virus subgroups in a nucleic acid hybridization assay.

Authors:  W M Sullender; G W Wertz
Journal:  J Clin Microbiol       Date:  1991-06       Impact factor: 5.948
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