Literature DB >> 3183465

A Mobile Oocyte Incubation Unit (MOIU): a device for improvement of the gamete intrafallopian transfer (GIFT) program.

M T Shih1, M H Yu, T Y Chu, D Sun, C K Lee, C T Hsu.   

Abstract

Forty couples with infertility due to various causes were selected for the gamete intrafallopian transfer (GIFT) program at our hospital. When the first 21 couples (Group A) had been treated in the program, the rate of pregnancy achieved was 23.8%, which did not seem satisfactory. This might have been caused by the distance between the embryo laboratory and the operating room. To eliminate this defect, a Mobile Oocyte Incubation Unit (MOIU) was designed. This is actually a compact laboratory that can be placed in the operating room. After the MOIU was utilized, the rate of pregnancy for the following 19 couples (Group B) increased to 42.1%. The MOIU has helped improve the performance of the GIFT program by increasing the stability of the pH value of the culture medium (Chetkowski R, et al.: J Vitro Fert Embryo Transfer 1985;2:207), lessening the exposure of the gametes to air and room temperature, and most importantly, shortening the time required for a GIFT procedure from 45-100 to 15-30 min. We expect that the MOIU will eventually become an integral part of the standard equipment for the GIFT program and make the program more successful and reliable in the treatment of infertility.

Entities:  

Mesh:

Year:  1988        PMID: 3183465     DOI: 10.1007/bf01131120

Source DB:  PubMed          Journal:  J In Vitro Fert Embryo Transf        ISSN: 0740-7769


  11 in total

1.  Gamete intrafallopian transfer in the treatment of infertility: the first series at the University of Palermo.

Authors:  G Guastella; G Comparetto; R Palermo; E Cefalù; R Ciriminna; E Cittadini
Journal:  Fertil Steril       Date:  1986-09       Impact factor: 7.329

2.  Laparoscopic recovery of preovulatory human oocytes after priming of ovaries with gonadotrophins.

Authors:  P C Steptoe; R G Edwards
Journal:  Lancet       Date:  1970-04-04       Impact factor: 79.321

3.  Test-tube babies, 1981.

Authors:  R G Edwards
Journal:  Nature       Date:  1981-09-24       Impact factor: 49.962

4.  Effect of variation of in vitro culture techniques upon oocyte fertilization and embryo development in human in vitro fertilization procedures.

Authors:  R P Marrs; H Saito; B Yee; F Sato; J Brown
Journal:  Fertil Steril       Date:  1984-04       Impact factor: 7.329

5.  Comparison of two clomiphene citrate dosage regimens for follicular recruitment in an in vitro fertilization program.

Authors:  M M Quigley; N F Maklad; D P Wolf
Journal:  Fertil Steril       Date:  1983-08       Impact factor: 7.329

6.  Clinical applications of techniques used in human in vitro fertilization research.

Authors:  R P Marrs; J M Vargyas; H Saito; W E Gibbons; T Berger; D R Mishell
Journal:  Am J Obstet Gynecol       Date:  1983-07-01       Impact factor: 8.661

7.  Preliminary experiences with gamete intrafallopian transfer (GIFT).

Authors:  R H Asch; J P Balmaceda; L R Ellsworth; P C Wong
Journal:  Fertil Steril       Date:  1986-03       Impact factor: 7.329

8.  Steroidogenesis in preovulatory follicles of patients given human menopausal and chorionic gonadotrophins as judged by the radioimmunoassay of steroids in follicular fluid.

Authors:  R E Fowler; R G Edwards; D E Walters; S T Chan; P C Steptoe
Journal:  J Endocrinol       Date:  1978-05       Impact factor: 4.286

9.  Optimization of hydrogen-ion concentration during aspiration of oocytes and culture and transfer of embryos.

Authors:  R J Chetkowski; T E Nass; D W Matt; F Hamilton; K A Steingold; D Randle; D R Meldrum
Journal:  J In Vitro Fert Embryo Transf       Date:  1985-12

10.  Human menopausal gonadotropin/human chorionic gonadotropin follicular maturation for oocyte aspiration: phase I, 1981.

Authors:  J E Garcia; G S Jones; A A Acosta; G Wright
Journal:  Fertil Steril       Date:  1983-02       Impact factor: 7.329

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