| Literature DB >> 31834526 |
Jira Chansaenroj1, Nasamon Wanlapakorn1,2, Chokchai Ngamsaithong3, Thanunrat Thongmee1, Natthaphon Na Nakorn4, Padet Siriyasatien5, Sompong Vongpunsawad1, Yong Poovorawan6.
Abstract
An outbreak of chikungunya virus (CHIKV) infection occurred in southwest Bangkok during the 2018 rainy season. The envelope glycoprotein E1 gene sequence of the infecting strain belonged to an East/Central/South African lineage with alanine at residue 226. Mutations in the predicted E1 (K211E) and E2 (V264A) proteins of CHIKV were identified in CHIKV-infected patients and in an Aedes aegypti mosquito. Analysis of the complete genome sequences showed marked differences from the strains causing previous outbreaks in Thailand in 2008-2009 and 2013 but showed similarities to strains from more recent CHIKV outbreaks in South and Southeast Asia.Entities:
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Year: 2019 PMID: 31834526 DOI: 10.1007/s00705-019-04509-1
Source DB: PubMed Journal: Arch Virol ISSN: 0304-8608 Impact factor: 2.574