Mansoureh Bajelan1, Negar Etehad Roodi1,2, Mahdy Hasanzadeh Daloee3, Mansoureh Farhangnia2, Ali Samadi Kuchaksaraei1,2. 1. Cellular and Molecular Research Centre, Iran University of Medical Science, Tehran, Iran. 2. Cardiovascular Research Center, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran. 3. Department of Tissue Engineering & Regenerative Medicine, Iran University of Medical Science, Tehran, Iran.
Abstract
BACKGROUND: Age-related morbidity and mortality rates from coronary heart disease (CHD) are higher in men than in women. Abnormal androgen levels cause a variety of abnormal symptoms in men. Testosterone and estrogen are the main sex hormone in men and women, respectively, and studies have shown that they have important roles in cardiovascular health and disease. METHODS: We measured testosterone and estrogen in 102 men with coronary heart disease and 45 controls. Blood samples were collected from subjects and plasma testosterone and estrogen were measured by ELISA. RESULTS: Men with coronary heart disease had less testosterone (OD Ratio: 0.782) and estrogen (OD Ratio: 0.955) than controls. CONCLUSION: Low testosterone and estrogen levels correlate with coronary artery disease.
BACKGROUND: Age-related morbidity and mortality rates from coronary heart disease (CHD) are higher in men than in women. Abnormal androgen levels cause a variety of abnormal symptoms in men. Testosterone and estrogen are the main sex hormone in men and women, respectively, and studies have shown that they have important roles in cardiovascular health and disease. METHODS: We measured testosterone and estrogen in 102 men with coronary heart disease and 45 controls. Blood samples were collected from subjects and plasma testosterone and estrogen were measured by ELISA. RESULTS: Men with coronary heart disease had less testosterone (OD Ratio: 0.782) and estrogen (OD Ratio: 0.955) than controls. CONCLUSION: Low testosterone and estrogen levels correlate with coronary artery disease.
Authors: Giovanni Corona; Elisa Maseroli; Giulia Rastrelli; Andrea M Isidori; Alessandra Sforza; Edoardo Mannucci; Mario Maggi Journal: Expert Opin Drug Saf Date: 2014-08-19 Impact factor: 4.250
Authors: Molly M Shores; Mary L Biggs; Alice M Arnold; Nicholas L Smith; W T Longstreth; Jorge R Kizer; Calvin H Hirsch; Anne R Cappola; Alvin M Matsumoto Journal: J Clin Endocrinol Metab Date: 2014-03-14 Impact factor: 5.958