Nondigestible Oligosaccharides with Anti-obesity Effects.

Obesity has an important influence on health conditions, causing multitude complications and comorbidities, and drug therapy is considered as one of the treatment strategies. Nowadays, there is an increasing interest in the study of intestinal microbiota regulation of obesity, as well as an increasing number of agricultural and sideline products are found to have anti-obesity potential. In the present review, we summarize an overview of current known and potential anti-obesity oligosaccharides and their molecular structures. We describe their anti-obesity potential activity and the molecular structure associated with this activity, the regulation of intestinal microbiota composition and its mechanism of action, including regulation of short-chain fatty acids (SCFAs) pathway and altering bile acids (BAs) pathway. This review will provide new ideas for us to develop new anti-obese functional foods.