Yanna Zhu1, Hao Zheng1, Zhiyong Zou2, Jin Jing1, Yinghua Ma2, Haijun Wang2, Jiayou Luo3, Xin Zhang4, Chunyan Luo5, Hong Wang6, Haiping Zhao7, Dehong Pan8, Per Sangild9, Biraj M Karmacharya10, Jun Ma2, Yajun Chen1. 1. Department of Maternal and Child Health, School of Public Health, Sun Yat-sen University. 2. Institute of Child and Adolescent Health, School of Public Health, Peking University. 3. Department of Maternal and Child Health, School of Public Health, Central South University. 4. School of Public Health, Tianjin Medical University. 5. Shanghai Municipal Center for Disease Control and Prevention & Shanghai Institute of Preventive Medicine. 6. Chongqing Medical University. 7. Ningxia Medical University. 8. Liaoning Health Supervision Bureau. 9. Department of Nutrition and Sport, University of Copenhagen. 10. Department of Community Medicine, Kathmandu University, Nepal. & Sun Yat-sen Global Health Institute, Sun Yat-sen University.
Abstract
AIMS: Metabolic syndrome (MetS) has become a worldwide epidemic; however, few studies have described its status in Chinese children. This study aimed to estimate MetS status and its associations with geography, economic development, birth weight, and parental education of Chinese children and adolescents. METHODS: Data were derived from 15,045 participants aged 7-18 years across seven Chinese provinces. Physical measurement and blood tests were conducted to assess the five classical MetS components described by the International Diabetes Federation, including abdominal obesity (the essential component), high blood pressure, low high-density cholesterol (HDL-C), high triglyceride, and elevated fasting glucose (FG). Logistic regression was adopted to explore possible associations between MetS and other factors. RESULTS: Overall, MetS prevalence was 2.3%, higher in males (2.8% vs. 1.7% in females), northern regions (3.1%), more developed regions (2.9%), and older participants (aged 16-18 years) (P＜0.05 for all). Among the five MetS components, abdominal obesity and low HDL-C level were most prevalent (21.8% and 14.4%), and 35.9% of the participants had at least one component. In logistic regression, MetS itself did not correlate with birth weight or parental education. High birth weight was positively correlated with abdominal obesity (odds ratio, 1.48) butnegatively associated with elevated FG (odds ratio, 0.49). Concusions: MetS itself was not common in Chinese children and adolescents, whereas its certain components were far more prevalent. Children from North China, more-developed areas, and at an older age were more likely to develop MetS. Strategies designed to prevent pediatric MetS in China should focus on prevalent components as well as its geographic and economic development predilections.
AIMS: Metabolic syndrome (MetS) has become a worldwide epidemic; however, few studies have described its status in Chinese children. This study aimed to estimate MetS status and its associations with geography, economic development, birth weight, and parental education of Chinese children and adolescents. METHODS: Data were derived from 15,045 participants aged 7-18 years across seven Chinese provinces. Physical measurement and blood tests were conducted to assess the five classical MetS components described by the International Diabetes Federation, including abdominal obesity (the essential component), high blood pressure, low high-density cholesterol (HDL-C), high triglyceride, and elevated fasting glucose (FG). Logistic regression was adopted to explore possible associations between MetS and other factors. RESULTS: Overall, MetS prevalence was 2.3%, higher in males (2.8% vs. 1.7% in females), northern regions (3.1%), more developed regions (2.9%), and older participants (aged 16-18 years) (P＜0.05 for all). Among the five MetS components, abdominal obesity and low HDL-C level were most prevalent (21.8% and 14.4%), and 35.9% of the participants had at least one component. In logistic regression, MetS itself did not correlate with birth weight or parental education. High birth weight was positively correlated with abdominal obesity (odds ratio, 1.48) butnegatively associated with elevated FG (odds ratio, 0.49). Concusions: MetS itself was not common in Chinese children and adolescents, whereas its certain components were far more prevalent. Children from North China, more-developed areas, and at an older age were more likely to develop MetS. Strategies designed to prevent pediatric MetS in China should focus on prevalent components as well as its geographic and economic development predilections.
Entities:
Keywords:
Abdominal obesity; Children and adolescents; Metabolic syndrome
Authors: Charles J Glueck; Jessica G Woo; Philip R Khoury; John A Morrison; Stephen R Daniels; Ping Wang Journal: Metabolism Date: 2015-01-10 Impact factor: 8.694
Authors: Sarah D de Ferranti; Kimberlee Gauvreau; David S Ludwig; Ellis J Neufeld; Jane W Newburger; Nader Rifai Journal: Circulation Date: 2004-10-11 Impact factor: 29.690