Literature DB >> 31826328

Recent developments in the use of organic-inorganic nanohybrids for drug delivery.

Danushika C Manatunga1, V Umayangana Godakanda1, Rohini M de Silva1, K M Nalin de Silva1.   

Abstract

Organic-inorganic nanohybrid (OINH) structures providing a versatile platform for drug delivery with improved characteristics are an area which has gained recent attention. Much effort has been taken to develop these structures to provide a viable treatment options for much alarming diseases such as cancer, bone destruction, neurological disorders, and so on. This review focuses on current work carried out in producing different types of hybrid drug carriers identifying their properties, fabrication techniques, and areas where they have been applied. A brief introduction on understating the requirement for blending organic-inorganic components into a nanohybrid drug carrier is followed with an elaboration given about the different types of OINHs developed currently highlighting their properties and applications. Then, different fabrication techniques are discussed given attention to surface functionalization, one-pot synthesis, wrapping, and electrospinning methods. Finally, it is concluded by briefing the challenges that are remaining to be addressed to obtain multipurpose nanohybrid drug carriers with wider applicability. This article is categorized under: Therapeutic Approaches and Drug Discovery > Emerging Technologies.
© 2019 Wiley Periodicals, Inc.

Entities:  

Keywords:  drug delivery; nanomaterials; organic-inorganic hybrids

Mesh:

Substances:

Year:  2019        PMID: 31826328     DOI: 10.1002/wnan.1605

Source DB:  PubMed          Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol        ISSN: 1939-0041


  3 in total

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Authors:  M Shanika Fernando; A K D V K Wimalasiri; Karolina Dziemidowicz; Gareth R Williams; K R Koswattage; D P Dissanayake; K M Nalin de Silva; Rohini M de Silva
Journal:  ACS Omega       Date:  2021-03-18

2.  Oxygen and Drug-Carrying Periodic Mesoporous Organosilicas for Enhanced Cell Viability under Normoxic and Hypoxic Conditions.

Authors:  Ravi Kumar; Nermin Seda Kehr
Journal:  Int J Mol Sci       Date:  2022-04-14       Impact factor: 6.208

Review 3.  Polymer-Based Hybrid Nanoarchitectures for Cancer Therapy Applications.

Authors:  Arun Kumar; Mirkomil Sharipov; Abbaskhan Turaev; Shavkatjon Azizov; Ismatdjan Azizov; Edwin Makhado; Abbas Rahdar; Deepak Kumar; Sadanand Pandey
Journal:  Polymers (Basel)       Date:  2022-07-26       Impact factor: 4.967

  3 in total

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