Literature DB >> 31825254

Essential Role of Nonessential Amino Acid Glutamine in Atherosclerotic Cardiovascular Disease.

Jinna Chen1, Shulei Zhang1, Jiaxiong Wu1, Shiyuan Wu2, Gaosheng Xu2, Dangheng Wei1.   

Abstract

Atherosclerosis is a major disease that seriously harms human health and is known as the "number one killer" in developed countries and the leading cause of death worldwide. Glutamine is the most abundant nonessential amino acid in the human blood that has multifaceted effects on the body. Recent studies showed that glutamine is negatively corrected with the progression of atherosclerotic lesions. In this review, we focused on the relationship of glutamine with macrophage polarization, nitrification stress, oxidative stress injury, myocardial ischemia-reperfusion injury, and therapeutic angiogenesis to review its roles in atherosclerotic cardiovascular disease.

Entities:  

Keywords:  angiogenesis; atherosclerosis; glutamine; ischemia–reperfusion; macrophages polarization

Year:  2019        PMID： 31825254     DOI： 10.1089/dna.2019.5034

Source DB:  PubMed          Journal:  DNA Cell Biol        ISSN： 1044-5498            Impact factor:   3.311


  8 in total

1.  Plasma Metabolomics Analysis Identifies Abnormal Energy, Lipid, and Amino Acid Metabolism in Abdominal Aortic Aneurysms.

Authors:  Yaming Guo; Shuwei Wan; Mingli Han; Yubo Zhao; Chuang Li; Gaopo Cai; Shuai Zhang; Zhi Sun; Xinhua Hu; Hui Cao; Zhen Li
Journal:  Med Sci Monit       Date:  2020-12-01

Review 2.  Small, Dense Low-Density Lipoprotein-Cholesterol and Atherosclerosis: Relationship and Therapeutic Strategies.

Authors:  Xiao Jin; Shengjie Yang; Jing Lu; Min Wu
Journal:  Front Cardiovasc Med       Date:  2022-02-10

Review 3.  The Role of Amino Acids in Endothelial Biology and Function.

Authors:  Meng Li; Yanqing Wu; Lei Ye
Journal:  Cells       Date:  2022-04-18       Impact factor: 7.666

4.  Metabolomic Profiling of Angiotensin-II-Induced Abdominal Aortic Aneurysm in Ldlr-/- Mice Points to Alteration of Nitric Oxide, Lipid, and Energy Metabolisms.

Authors:  Juan Manuel Chao de la Barca; Alexis Richard; Pauline Robert; Maroua Eid; Olivier Fouquet; Lydie Tessier; Céline Wetterwald; Justine Faure; Celine Fassot; Daniel Henrion; Pascal Reynier; Laurent Loufrani
Journal:  Int J Mol Sci       Date:  2022-06-07       Impact factor: 6.208

5.  Cross-sectional associations between cardiorespiratory fitness and NMR-derived metabolic biomarkers in children - the PANIC study.

Authors:  Eero A Haapala; Marja H Leppänen; Maarit Lehti; Niina Lintu; Tuomo Tompuri; Anna Viitasalo; Ursula Schwab; Timo A Lakka
Journal:  Front Endocrinol (Lausanne)       Date:  2022-09-23       Impact factor: 6.055

Review 6.  Clinical features, pathogenesis, and management of stroke-like episodes due to MELAS.

Authors:  Syuichi Tetsuka; Tomoko Ogawa; Ritsuo Hashimoto; Hiroyuki Kato
Journal:  Metab Brain Dis       Date:  2021-06-12       Impact factor: 3.584

Review 7.  Intestinal Ca2+ absorption revisited: A molecular and clinical approach.

Authors:  Vanessa A Areco; Romina Kohan; Germán Talamoni; Nori G Tolosa de Talamoni; María E Peralta López
Journal:  World J Gastroenterol       Date:  2020-06-28       Impact factor: 5.742

Review 8.  The Effects of Pro-Inflammatory and Anti-Inflammatory Agents for the Suppression of Intimal Hyperplasia: An Evidence-Based Review.

Authors:  Rohaina Che Man; Nadiah Sulaiman; Mohamad Fikeri Ishak; Ruszymah Bt Hj Idrus; Mohd Ramzisham Abdul Rahman; Muhammad Dain Yazid
Journal:  Int J Environ Res Public Health       Date:  2020-10-26       Impact factor: 3.390
  8 in total

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