Literature DB >> 31823266

Water quality and chronic kidney disease of unknown aetiology (CKDu) in the dry zone region of Sri Lanka: impacts on well-being of village communities and the way forward.

Uthpala Pinto1, Bhadranie Thoradeniya2, Basant Maheshwari3.   

Abstract

There has been a growing concern in the dry zone of Sri Lanka that the contaminated surface and ground waters and ecohydrological changes are possibly linked to a number of health issues and overall well-being of village communities, including the widespread renal failure termed as chronic kidney disease of unknown aetiology (CKDu). Two types of data were collected for this study, namely qualitative data from key informant interviews and abstracts of 33 peer-reviewed research articles during the past decade. A total of 35 key informants were recruited, mainly from communities in the northern dry zone region where a higher number of CKDu patients have been reported. The interview transcripts were examined using a range of techniques including content, thematic and semantic network analyses. The findings of the research articles were explored through a word cloud analysis. The study indicates that CKDu seems to be influenced by multifactorial ecohydrological changes linked to anthropogenic stressors such as inefficient use of fertilisers and weedicides in agriculture. This situation is made further complicated by factors such as high fluoride level and hardness of local groundwater. Inappropriate agricultural and water policies and poor governance are other factors, particularly little or no restriction on the use of agrochemicals and pumping of groundwater and limited access to clean municipal water supplies. The key informants indicated grave concerns on the flow on effects of poor surface and groundwater quality in the region on health, livelihood and well-being of communities. There are also inevitable economic implications such as loss of human capital and families losing assets to pay for ongoing health issues. The study highlighted the need for more in-depth research to better understand how the surface and groundwater quality influence CKDu and other health conditions in the region. Furthermore, there is a need for implementing an active water quality management strategy with emphasis on developing locally relevant guidelines, educational programmes and integrated heath monitoring programmes in the region.

Entities:  

Keywords:  CKDu; Communication; Farming; Groundwater; Kidney disease; Science communication; Stakeholder engagement; Water quality management

Mesh:

Year:  2019        PMID: 31823266     DOI: 10.1007/s11356-019-06669-8

Source DB:  PubMed          Journal:  Environ Sci Pollut Res Int        ISSN: 0944-1344            Impact factor:   4.223


  11 in total

Review 1.  Groundwater and human development: challenges and opportunities in livelihoods and environment.

Authors:  T Shah
Journal:  Water Sci Technol       Date:  2005       Impact factor: 1.915

2.  Nephrotoxic contaminants in drinking water and urine, and chronic kidney disease in rural Sri Lanka.

Authors:  Tewodros Rango; Marc Jeuland; Herath Manthrithilake; Peter McCornick
Journal:  Sci Total Environ       Date:  2015-03-14       Impact factor: 7.963

3.  Drinking water quality and chronic kidney disease of unknown etiology (CKDu): synergic effects of fluoride, cadmium and hardness of water.

Authors:  Hewa M S Wasana; Dharshani Aluthpatabendi; W M T D Kularatne; Pushpa Wijekoon; Rohan Weerasooriya; Jayasundera Bandara
Journal:  Environ Geochem Health       Date:  2015-04-10       Impact factor: 4.609

4.  Quest to identify geochemical risk factors associated with chronic kidney disease of unknown etiology (CKDu) in an endemic region of Sri Lanka-a multimedia laboratory analysis of biological, food, and environmental samples.

Authors:  Keith E Levine; Jennifer Hoponick Redmon; Myles F Elledge; Kamani P Wanigasuriya; Kristin Smith; Breda Munoz; Vajira A Waduge; Roshini J Periris-John; Nalini Sathiakumar; James M Harrington; Donna S Womack; Rajitha Wickremasinghe
Journal:  Environ Monit Assess       Date:  2016-09-03       Impact factor: 2.513

5.  Chronic renal failure among farm families in cascade irrigation systems in Sri Lanka associated with elevated dietary cadmium levels in rice and freshwater fish (Tilapia).

Authors:  J M R S Bandara; D M A N Senevirathna; D M R S B Dasanayake; V Herath; J M R P Bandara; T Abeysekara; K H Rajapaksha
Journal:  Environ Geochem Health       Date:  2008-01-17       Impact factor: 4.609

6.  Perspectives on impacts of water quality on agriculture and community well-being-a key informant study from Sri Lanka.

Authors:  Bhadranie Thoradeniya; Uthpala Pinto; Basant Maheshwari
Journal:  Environ Sci Pollut Res Int       Date:  2017-11-04       Impact factor: 4.223

7.  Source of drinking water and other risk factors for dental fluorosis in Sri Lanka.

Authors:  Wim van der Hoek; Lilani Ekanayake; Lorraine Rajasooriyar; Ravi Karunaratne
Journal:  Int J Environ Health Res       Date:  2003-09       Impact factor: 3.411

8.  Importance of Arsenic and pesticides in epidemic chronic kidney disease in Sri Lanka.

Authors:  Channa Jayasumana; Ranil Gajanayake; Sisira Siribaddana
Journal:  BMC Nephrol       Date:  2014-07-28       Impact factor: 2.388

9.  Epidemiology of chronic kidney disease, with special emphasis on chronic kidney disease of uncertain etiology, in the north central region of Sri Lanka.

Authors:  Kithsiri Bandara Jayasekara; Dhammika Menike Dissanayake; Ramiah Sivakanesan; Asanga Ranasinghe; Ranawaka Hewage Karunarathna; Gardiye Waligamage Gamini Priyantha Kumara
Journal:  J Epidemiol       Date:  2015-03-17       Impact factor: 3.211

10.  Chronic kidney disease of uncertain aetiology: prevalence and causative factors in a developing country.

Authors:  Nihal Jayatilake; Shanthi Mendis; Palitha Maheepala; Firdosi R Mehta
Journal:  BMC Nephrol       Date:  2013-08-27       Impact factor: 2.388

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  3 in total

Review 1.  Multi-pronged research on endemic chronic kidney disease of unknown etiology in Sri Lanka: a systematic review.

Authors:  Dinushi Arambegedara; Saroj Jayasinghe; Preethi Udagama
Journal:  Environ Sci Pollut Res Int       Date:  2021-11-19       Impact factor: 5.190

Review 2.  Unstable Housing and Kidney Disease: A Primer.

Authors:  Tessa K Novick; Margot Kushel; Deidra Crews
Journal:  Kidney Med       Date:  2022-03-07

3.  Evaluation of Performance of Existing RO Drinking Water Stations in the North Central Province, Sri Lanka.

Authors:  Suresh Indika; Yuansong Wei; Dazhou Hu; Jegetheeswaran Ketharani; Tharindu Ritigala; Titus Cooray; M A C K Hansima; Madhubashini Makehelwala; K B S N Jinadasa; Sujithra K Weragoda; Rohan Weerasooriya
Journal:  Membranes (Basel)       Date:  2021-05-24
  3 in total

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