Literature DB >> 31822204

The Year in Basic Thyroidology.

Sheue-Yann Cheng1.   

Abstract

Basic research in 2019 yielded exciting discoveries and advancements in thyroidology. Specifically, there have been breakthroughs in our understanding of the molecular actions of thyroid hormone and thyroid hormone receptors, thyroid hormone metabolism and transport, autoimmunity, and thyroid cancer. Next, I summarize important studies published over the past year and whose major data I presented during the 89th American Thyroid Association annual meeting at the opening plenary session The Year in Thyroidology.

Entities:  

Keywords:  autoimmunity; thyroid cancer; thyroid hormone; thyroid hormone metabolism and transport; thyroid hormone receptors

Mesh:

Substances:

Year:  2020        PMID: 31822204      PMCID: PMC6983739          DOI: 10.1089/thy.2019.0768

Source DB:  PubMed          Journal:  Thyroid        ISSN: 1050-7256            Impact factor:   6.568


  28 in total

1.  BET bromodomain inhibition as a therapeutic strategy to target c-Myc.

Authors:  Jake E Delmore; Ghayas C Issa; Madeleine E Lemieux; Peter B Rahl; Junwei Shi; Hannah M Jacobs; Efstathios Kastritis; Timothy Gilpatrick; Ronald M Paranal; Jun Qi; Marta Chesi; Anna C Schinzel; Michael R McKeown; Timothy P Heffernan; Christopher R Vakoc; P Leif Bergsagel; Irene M Ghobrial; Paul G Richardson; Richard A Young; William C Hahn; Kenneth C Anderson; Andrew L Kung; James E Bradner; Constantine S Mitsiades
Journal:  Cell       Date:  2011-09-01       Impact factor: 41.582

2.  Treatment of prostate cancer by radioiodine therapy after tissue-specific expression of the sodium iodide symporter.

Authors:  C Spitzweg; M K O'Connor; E R Bergert; D J Tindall; C Y Young; J C Morris
Journal:  Cancer Res       Date:  2000-11-15       Impact factor: 12.701

3.  Biased signaling by thyroid-stimulating hormone receptor-specific antibodies determines thyrocyte survival in autoimmunity.

Authors:  Syed A Morshed; Risheng Ma; Rauf Latif; Terry F Davies
Journal:  Sci Signal       Date:  2018-01-23       Impact factor: 8.192

4.  Evidence for hormonal control of heart regenerative capacity during endothermy acquisition.

Authors:  Kentaro Hirose; Alexander Y Payumo; Stephen Cutie; Alison Hoang; Hao Zhang; Romain Guyot; Dominic Lunn; Rachel B Bigley; Hongyao Yu; Jiajia Wang; Megan Smith; Ellen Gillett; Sandra E Muroy; Tobias Schmid; Emily Wilson; Kenneth A Field; DeeAnn M Reeder; Malcom Maden; Michael M Yartsev; Michael J Wolfgang; Frank Grützner; Thomas S Scanlan; Luke I Szweda; Rochelle Buffenstein; Guang Hu; Frederic Flamant; Jeffrey E Olgin; Guo N Huang
Journal:  Science       Date:  2019-03-07       Impact factor: 47.728

5.  Potentiated anti-tumor effects of BETi by MEKi in anaplastic thyroid cancer.

Authors:  Xuguang Zhu; Sunmi Park; Woo Kyung Lee; Sheue-Yann Cheng
Journal:  Endocr Relat Cancer       Date:  2019-09       Impact factor: 5.678

6.  No Effect of the Thr92Ala Polymorphism of Deiodinase-2 on Thyroid Hormone Parameters, Health-Related Quality of Life, and Cognitive Functioning in a Large Population-Based Cohort Study.

Authors:  Hanneke J C M Wouters; Hannah C M van Loon; Melanie M van der Klauw; Martin F Elderson; Sandra N Slagter; Anneke Muller Kobold; Ido P Kema; Thera P Links; Jana V van Vliet-Ostaptchouk; Bruce H R Wolffenbuttel
Journal:  Thyroid       Date:  2016-12-15       Impact factor: 6.568

7.  Lifetime cancer risks in individuals with germline PTEN mutations.

Authors:  Min-Han Tan; Jessica L Mester; Joanne Ngeow; Lisa A Rybicki; Mohammed S Orloff; Charis Eng
Journal:  Clin Cancer Res       Date:  2012-01-15       Impact factor: 12.531

Review 8.  The sodium iodide symporter (NIS): regulation and approaches to targeting for cancer therapeutics.

Authors:  Takahiko Kogai; Gregory A Brent
Journal:  Pharmacol Ther       Date:  2012-06-29       Impact factor: 12.310

9.  Type 2 deiodinase polymorphism causes ER stress and hypothyroidism in the brain.

Authors:  Sungro Jo; Tatiana L Fonseca; Barbara M L C Bocco; Gustavo W Fernandes; Elizabeth A McAninch; Anaysa P Bolin; Rodrigo R Da Conceição; Joao Pedro Werneck-de-Castro; Daniele L Ignacio; Péter Egri; Dorottya Németh; Csaba Fekete; Maria Martha Bernardi; Victoria D Leitch; Naila S Mannan; Katharine F Curry; Natalie C Butterfield; J H Duncan Bassett; Graham R Williams; Balázs Gereben; Miriam O Ribeiro; Antonio C Bianco
Journal:  J Clin Invest       Date:  2018-12-03       Impact factor: 14.808

10.  Mutated Thyroid Hormone Transporter OATP1C1 Associates with Severe Brain Hypometabolism and Juvenile Neurodegeneration.

Authors:  Petter Strømme; Stefan Groeneweg; Elaine C Lima de Souza; Chantal Zevenbergen; Anette Torgersbråten; Asbjørn Holmgren; Ebrar Gurcan; Marcel E Meima; Robin P Peeters; W Edward Visser; Linda Høneren Johansson; Almira Babovic; Henrik Zetterberg; Heike Heuer; Eirik Frengen; Doriana Misceo; Theo J Visser
Journal:  Thyroid       Date:  2018-11       Impact factor: 6.568

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