| Literature DB >> 31821138 |
Joanne Schneider1, Mary Patterson1, Xavier F Jimenez2.
Abstract
Tricyclic antidepressants (TCAs) were originally designed and marketed for treating depression, but over time they have been applied to a variety of conditions, mostly off-label. TCAs can serve as first-line or augmenting drugs for neuropathic pain, headache, migraine, gastrointestinal syndromes, fibromyalgia, pelvic pain, insomnia, and psychiatric conditions other than depression. This article reviews pharmacology, dosing, and safety considerations for these uses.Entities:
Year: 2019 PMID: 31821138 DOI: 10.3949/ccjm.86a.19005
Source DB: PubMed Journal: Cleve Clin J Med ISSN: 0891-1150 Impact factor: 2.321