Literature DB >> 31819271

Molecular glue concept solidifies.

Kheewoong Baek1, Brenda A Schulman2.   

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Year:  2020        PMID: 31819271     DOI: 10.1038/s41589-019-0414-3

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN: 1552-4450            Impact factor:   15.040


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  2 in total

1.  Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex.

Authors:  Dirksen E Bussiere; Lili Xie; Honnappa Srinivas; Wei Shu; Ashley Burke; Celine Be; Junping Zhao; Adarsh Godbole; Dan King; Rajeshri G Karki; Viktor Hornak; Fangmin Xu; Jennifer Cobb; Nathalie Carte; Andreas O Frank; Alexandra Frommlet; Patrick Graff; Mark Knapp; Aleem Fazal; Barun Okram; Songchun Jiang; Pierre-Yves Michellys; Rohan Beckwith; Hans Voshol; Christian Wiesmann; Jonathan M Solomon; Joshiawa Paulk
Journal:  Nat Chem Biol       Date:  2019-12-09       Impact factor: 15.040

2.  Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15.

Authors:  Tyler B Faust; Hojong Yoon; Radosław P Nowak; Katherine A Donovan; Zhengnian Li; Quan Cai; Nicholas A Eleuteri; Tinghu Zhang; Nathanael S Gray; Eric S Fischer
Journal:  Nat Chem Biol       Date:  2019-11-04       Impact factor: 15.040

  2 in total
  4 in total

1.  Exploiting Ubiquitin Ligases for Induced Target Degradation as an Antiviral Strategy.

Authors:  Rati Verma
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

2.  Ubiquitination and degradation of SUMO1 by small-molecule degraders extends survival of mice with patient-derived tumors.

Authors:  Anita C Bellail; Hong Ri Jin; Ho-Yin Lo; Sung Han Jung; Chafiq Hamdouchi; Daeho Kim; Ryan K Higgins; Maximilian Blanck; Carlos le Sage; Benedict C S Cross; Jing Li; Amber L Mosley; Aruna B Wijeratne; Wen Jiang; Manali Ghosh; Yin Quan Zhao; Paula M Hauck; Anantha Shekhar; Chunhai Hao
Journal:  Sci Transl Med       Date:  2021-10-13       Impact factor: 19.319

Review 3.  Targeted degradation of immune checkpoint proteins: emerging strategies for cancer immunotherapy.

Authors:  Jie Xu; Jean-Philippe Brosseau; Hubing Shi
Journal:  Oncogene       Date:  2020-10-06       Impact factor: 9.867

4.  Identification of Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators.

Authors:  Gisele Nishiguchi; Fatemeh Keramatnia; Jaeki Min; Yunchao Chang; Barbara Jonchere; Sourav Das; Marisa Actis; Jeanine Price; Divyabharathi Chepyala; Brandon Young; Kevin McGowan; P Jake Slavish; Anand Mayasundari; Jamie A Jarusiewicz; Lei Yang; Yong Li; Xiang Fu; Shalandus H Garrett; James B Papizan; Kiran Kodali; Junmin Peng; Shondra M Pruett Miller; Martine F Roussel; Charles Mullighan; Marcus Fischer; Zoran Rankovic
Journal:  J Med Chem       Date:  2021-05-27       Impact factor: 7.446

  4 in total

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