| Literature DB >> 31818836 |
Jiabin Liu1, Nabil Elkassabany2, Jashvant Poeran3, Alejandro Gonzalez Della Valle4, David H Kim5, Daniel Maalouf5, Stavros Memtsoudis5.
Abstract
OBJECTIVE: To determine if same-day discharge total knee arthroplasty (TKA) or total hip arthroplasty (THA) is not associated with increased risk of unplanned readmission and adverse outcomes within 30 days of surgery.Entities:
Keywords: health & safety; hip; knee; orthopaedic & trauma surgery
Year: 2019 PMID: 31818836 PMCID: PMC6924781 DOI: 10.1136/bmjopen-2019-031260
Source DB: PubMed Journal: BMJ Open ISSN: 2044-6055 Impact factor: 2.692
Patient demographic information and comorbidity
| Total knee arthroplasty | Total hip arthroplasty | |||||||||||||||
| LOS 0 | LOS 1 | LOS 2–3 | LOS 0 | LOS 1 | LOS 2–3 | |||||||||||
| Mean/N | Std/% | Mean/N | Std/% | P value* | Mean/N | Std/% | P value† | Mean/N | Std/% | Mean/N | Std/% | P value* | Mean/N | Std/% | P value† | |
| Age (year) | 65.18 | 9.67 | 65.40 | 8.98 | 0.194 | 66.61 | 9.49 | <0.001 | 61.46 | 10.67 | 62.13 | 10.68 | 0.002 | 65.07 | 11.33 | <0.001 |
| Sex | ||||||||||||||||
| Female | 1682 | 53.94 | 16 363 | 52.10 | 0.050 | 120 447 | 62.77 | <0.001 | 1214 | 45.78 | 13 254 | 44.75 | 0.309 | 61 006 | 56.37 | <0.001 |
| Male | 1436 | 46.06 | 15 041 | 47.90 | 71 427 | 37.23 | 1438 | 54.22 | 16 363 | 55.25 | 47 225 | 43.63 | ||||
| Race | ||||||||||||||||
| White | 2512 | 88.98 | 26 698 | 89.60 | 0.354 | 148 875 | 88.45 | <0.001 | 2213 | 90.40 | 25 540 | 90.76 | 0.217 | 83 651 | 89.17 | <0.001 |
| Black | 200 | 7.08 | 2080 | 6.98 | 14 103 | 8.38 | 162 | 6.62 | 1920 | 6.82 | 8108 | 8.64 | ||||
| Others | 111 | 3.93 | 1020 | 3.42 | 5330 | 3.17 | 73 | 2.98 | 681 | 2.42 | 2054 | 2.19 | ||||
| BMI | 32.09 | 6.39 | 32.18 | 6.17 | 0.419 | 33.06 | 6.91 | <0.001 | 29.16 | 5.39 | 29.69 | 5.73 | <0.001 | 30.33 | 6.41 | <0.001 |
| OR time (min) | 84.58 | 33.48 | 86.24 | 29.24 | 0.003 | 90.23 | 34.88 | <0.001 | 82.60 | 33.49 | 87.67 | 32.02 | 0.002 | 91.43 | 38.26 | <0.001 |
| ASA classification | ||||||||||||||||
| I/II | 1882 | 60.42 | 17 957 | 57.21 | 0.001 | 99 497 | 51.87 | <0.001 | 1958 | 73.83 | 20 148 | 68.07 | <0.001 | 62 496 | 57.76 | <0.001 |
| ≥III | 1233 | 39.58 | 13 432 | 42.79 | 92 336 | 48.13 | 694 | 26.17 | 9451 | 31.93 | 45 696 | 42.24 | ||||
| Diabetes | ||||||||||||||||
| Type II | 367 | 11.77 | 3699 | 11.78 | 0.983 | 25 932 | 13.51 | <0.001 | 182 | 6.86 | 2152 | 7.27 | 0.707 | 9967 | 9.20 | <0.001 |
| Type I | 93 | 2.98 | 955 | 3.04 | 7901 | 4.12 | 46 | 1.73 | 537 | 1.81 | 2892 | 2.67 | ||||
| Smoker | 234 | 7.50 | 2565 | 8.17 | 0.196 | 16 263 | 8.47 | 0.036 | 294 | 11.09 | 3696 | 12.48 | 0.037 | 14 317 | 13.22 | <0.001 |
| Function status | 11 | 0.35 | 139 | 0.45 | 0.647 | 1932 | 1.01 | <0.001 | 14 | 0.53 | 211 | 0.71 | 0.454 | 1885 | 1.75 | <0.001 |
| CHF | 4 | 0.13 | 43 | 0.14 | 0.901 | 483 | 0.25 | <0.001 | 2 | 0.08 | 25 | 0.08 | 0.878 | 272 | 0.25 | <0.001 |
| HTN | 1811 | 58.08 | 19 187 | 61.10 | 0.001 | 124 958 | 65.10 | <0.001 | 1185 | 44.68 | 14 516 | 49.01 | <0.001 | 61 084 | 56.41 | <0.001 |
| COPD | 82 | 2.63 | 732 | 2.33 | 0.294 | 6404 | 3.34 | <0.001 | 67 | 2.53 | 660 | 2.23 | 0.322 | 4108 | 3.79 | <0.001 |
| Liver disease | 0 | 4 | 0.01 | 0.529 | 27 | 0.01 | 0.792 | 1 | 0.04 | 2 | 0.01 | 0.113 | 22 | 0.02 | 0.222 | |
| Renal insufficiency | 3 | 0.10 | 28 | 0.09 | 0.900 | 242 | 0.13 | 0.201 | 3 | 0.11 | 22 | 0.07 | 0.491 | 191 | 0.18 | <0.001 |
| Cancer | 1 | 0.03 | 21 | 0.07 | 0.463 | 190 | 0.10 | 0.119 | 3 | 0.11 | 41 | 0.14 | 0.735 | 254 | 0.23 | 0.003 |
| Bleeding disorder | 49 | 1.57 | 445 | 1.42 | 0.488 | 3987 | 2.08 | <0.001 | 19 | 0.72 | 354 | 1.20 | 0.027 | 2168 | 2.00 | <0.001 |
*P value analysis between LOS 0 and LOS 1 groups.
†P value analysis among LOS 0, LOS 1 and LOS 2–3 groups.
ASA, American Society of Anesthesiologists; BMI, Body Mass Index; CHF, congestive heart failure; COPD, Chronic obstructive pulmonary disease; HTN, hypertension;LOS, length of stay (days); OR, Operating Room.
Incidence of complications with various LOS (per 100 patients), OR analysis, and propensity score matching (PM) analysis of complications in total knee arthroplasty (TKA)
| LOS 0 | LOS 1 | P value† | LOS 2–3 | P value* | TKA/Single variable regression | TKA/Multi-variable regression | TKA/PM/Incidence (%)* | ||||||||||
| OR | P value | 95% CI | OR | P value | 95% CI | LOS 0 | LOS 1 | P value | |||||||||
| Mortality | 0.16 | 0.08 | 0.123 | 0.1 | 0.253 | 2.10 | 0.132 | 0.80 to 5.51 | 1.78 | 0.295 | 0.60 to 5.27 | 0.14 | 0.00 | 0.045 | |||
| Unplanned readmission | 2.41 | 2.31 | 0.749 | 2.89 | <0.001 | 1.04 | 0.749 | 0.82 to 1.32 | 1.10 | 0.445 | 0.86 to 1.42 | 2.53 | 2.03 | 0.211 | |||
| Major complication | 0.96 | 0.53 | 0.003 | 0.64 | 0.006 | 1.81 | 0.003 | 1.22 to 2.67 | † | 1.94 | 0.001 | 1.29 to 2.92 | † | 0.96 | 0.32 | 0.003 | † |
| Any complication excluding transfusion | 2.98 | 1.99 | <0.001 | 2.74 | <0.001 | 1.51 | <0.001 | 1.21 to 1.89 | † | 1.55 | <0.001 | 1.22 to 1.96 | † | 2.92 | 1.53 | <0.001 | † |
| Any complication | 4.49 | 2.16 | <0.001 | 6.95 | <0.001 | 2.13 | <0.001 | 1.77 to 2.57 | † | 2.03 | <0.001 | 1.66 to 2.47 | † | 4.42 | 1.85 | <0.001 | † |
| Systemic infection | 1.67 | 1.28 | 0.070 | 1.73 | <0.001 | 1.31 | 0.071 | 0.98 to 1.75 | 1.30 | 0.098 | 0.95 to 1.79 | 1.60 | 1.03 | 0.061 | |||
| Wound infection | 0.77 | 0.72 | 0.753 | 0.88 | 0.015 | 1.07 | 0.753 | 0.70 to 1.63 | 0.99 | 0.963 | 0.61 to 1.59 | 0.68 | 0.43 | 0.207 | |||
| Cardiac/pulmonary complications | 0.67 | 0.37 | 0.009 | 0.44 | 0.023 | 1.84 | 0.010 | 1.16 to 2.94 | † | 1.95 | 0.007 | 1.20 to 3.16 | † | 0.68 | 0.25 | 0.018 | † |
*Propensity score matched 2796 patients per group.
†Indicates significance.
LOS, length of stay.
Incidence of complications with various LOS (per 100 patients), OR analysis and propensity score matching (PM) analysis of complications in total hip arthroplasty (THA)
| LOS 0 | LOS 1 | P value† | LOS 2–3 | P value* | THA/Single variable regression | THA/Multi-variable regression | THA/PM/Incidence(%)* | ||||||||||
| OR | P value | 95% CI | OR | P value | 95% CI | LOS 0 | LOS 1 | P value | |||||||||
| Mortality | 0.11 | 0.11 | 0.939 | 0.11 | 0.978 | 1.05 | 0.939 | 0.32 to 3.42 | 0.84 | 0.786 | 0.24 to 2.99 | 0.12 | 0.04 | 0.317 | |||
| Unplanned readmission | 1.62 | 2.04 | 0.144 | 3.26 | <0.001 | 0.79 | 0.145 | 0.58 to 1.08 | 0.84 | 0.292 | 0.60 to 1.16 | 1.64 | 2.05 | 0.287 | |||
| Major complication | 0.72 | 0.43 | 0.034 | 0.65 | <0.001 | 1.68 | 0.036 | 1.03 to 2.72 | 1.55 | 0.112 | 0.90 to 2.67 | 0.61 | 0.20 | 0.025 | |||
| Any complication excluding transfusion | 1.73 | 1.68 | 0.849 | 2.67 | <0.001 | 1.03 | 0.849 | 0.76 to 1.4 | 1.00 | 0.979 | 0.72 to 1.41 | 1.51 | 1.19 | 0.321 | |||
| Any complication | 3.13 | 2.86 | 0.420 | 9.76 | <0.001 | 1.1 | 0.420 | 0.87 to 1.38 | 1.12 | 0.363 | 0.87 to 1.44 | 2.91 | 2.17 | 0.102 | |||
| Systemic infection | 1.06 | 1.26 | 0.372 | 2.03 | <0.001 | 0.84 | 0.373 | 0.57 to 1.23 | 0.77 | 0.259 | 0.49 to 1.20 | 0.86 | 1.02 | 0.553 | |||
| Wound infection | 0.49 | 0.77 | 0.113 | 1.11 | <0.001 | 0.64 | 0.116 | 0.36 to 1.12 | 0.75 | 0.334 | 0.42 to 1.35 | 0.49 | 0.53 | 0.841 | |||
| Cardiac/pulmonary complications | 0.57 | 0.26 | 0.005 | 0.39 | 0.002 | 2.15 | 0.007 | 1.24 to 3.75 | † | 1.96 | 0.034 | 1.05 to 3.64 | † | 0.49 | 0.12 | 0.020 | † |
*Propensity score matched 2423 patients per group.
†Indicates significance.
LOS, length of stay.