Literature DB >> 31818824

Impact of Candida auris Infection in a Neutropenic Murine Model.

Steven R Torres1,2, Amber Pichowicz3, Fernando Torres-Velez2, Renjie Song4, Navjot Singh5, Erica Lasek-Nesselquist6, Magdia De Jesus7,2.   

Abstract

Candida auris has become a global public health threat due to its multidrug resistance and persistence. Currently, there are limited murine models to study C. auris infection. Those models use a combination of cyclophosphamide and cortisone acetate, suppressing both innate and adaptive immunity. Here, we compare C. auris infection in two neutrophil-depleted murine models in which innate immunity is targeted using the monoclonal antibodies 1A8 and RB6-8C5.
Copyright © 2020 American Society for Microbiology.

Entities:  

Keywords:  Candida auris; Ly6C; Ly6G; microbiome; neutrophil depletion; torticollis

Mesh：

Substances：

Year:  2020        PMID： 31818824      PMCID： PMC7038241          DOI： 10.1128/AAC.01625-19

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  24 in total

1.  Drosophila melanogaster as a model to study virulence and azole treatment of the emerging pathogen Candida auris.

Authors:  Sebastian Wurster; Ashwini Bandi; Nicholas D Beyda; Nathaniel D Albert; Nitya M Raman; Isaam I Raad; Dimitrios P Kontoyiannis
Journal:  J Antimicrob Chemother       Date:  2019-07-01       Impact factor: 5.790

2.  Cyclophosphamide enhances immunity by modulating the balance of dendritic cell subsets in lymphoid organs.

Authors:  Takeshi Nakahara; Hiroshi Uchi; Alexander M Lesokhin; Francesca Avogadri; Gabrielle A Rizzuto; Daniel Hirschhorn-Cymerman; Katherine S Panageas; Taha Merghoub; Jedd D Wolchok; Alan N Houghton
Journal:  Blood       Date:  2010-02-12       Impact factor: 22.113

3.  First report of sporadic cases of Candida auris in Colombia.

Authors:  Claudia M Parra-Giraldo; Sandra L Valderrama; Gloria Cortes-Fraile; Javier R Garzón; Beatriz E Ariza; Florent Morio; Melva Y Linares-Linares; Andrés Ceballos-Garzón; Alejandro de la Hoz; Catalina Hernandez; Carlos Alvarez-Moreno; Patrice Le Pape
Journal:  Int J Infect Dis       Date:  2018-02-05       Impact factor: 3.623

4.  Comparative virulence of Candida auris with Candida haemulonii, Candida glabrata and Candida albicans in a murine model.

Authors:  Hamed Fakhim; Afsane Vaezi; Eric Dannaoui; Anuradha Chowdhary; Davood Nasiry; Leila Faeli; Jacques F Meis; Hamid Badali
Journal:  Mycoses       Date:  2018-03-14       Impact factor: 4.377

5.  Donor-Derived Transmission of Candida auris During Lung Transplantation.

Authors:  Marwan M Azar; Sarah E Turbett; Jay A Fishman; Virginia M Pierce
Journal:  Clin Infect Dis       Date:  2017-09-15       Impact factor: 9.079

6.  First three reported cases of nosocomial fungemia caused by Candida auris.

Authors:  Wee Gyo Lee; Jong Hee Shin; Young Uh; Min Gu Kang; Soo Hyun Kim; Kyung Hwa Park; Hee-Chang Jang
Journal:  J Clin Microbiol       Date:  2011-06-29       Impact factor: 5.948

7.  Use of Ly6G-specific monoclonal antibody to deplete neutrophils in mice.

Authors:  Jean M Daley; Alan A Thomay; Michael D Connolly; Jonathan S Reichner; Jorge E Albina
Journal:  J Leukoc Biol       Date:  2007-09-20       Impact factor: 4.962

8.  The effect of cyclophosphamide on B cells and 'background' immunoglobulin-secreting cells in mice.

Authors:  N R Sabbele; A Van Oudenaren; R Benner
Journal:  Immunopharmacology       Date:  1988 Jan-Feb

9.  Two independent killing mechanisms of Candida albicans by human neutrophils: evidence from innate immunity defects.

Authors:  Roel P Gazendam; John L van Hamme; Anton T J Tool; Michel van Houdt; Paul J J H Verkuijlen; Martin Herbst; Johannes G Liese; Frank L van de Veerdonk; Dirk Roos; Timo K van den Berg; Taco W Kuijpers
Journal:  Blood       Date:  2014-06-19       Impact factor: 22.113

10.  The NDV-3A vaccine protects mice from multidrug resistant Candida auris infection.

Authors:  Shakti Singh; Priya Uppuluri; Zeinab Mamouei; Abdullah Alqarihi; Hana Elhassan; Samuel French; Shawn R Lockhart; Tom Chiller; John E Edwards; Ashraf S Ibrahim
Journal:  PLoS Pathog       Date:  2019-08-05       Impact factor: 6.823
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  11 in total

1.  An Immunocompromised Mouse Model of Candida auris Systemic Infection.

Authors:  Janet Herrada; Kyle Roberts; Ahmed Gamal; Lisa Long; Mahmoud A Ghannoum
Journal:  Methods Mol Biol       Date:  2022

2.  Innate immune responses against the fungal pathogen Candida auris.

Authors:  Yuanyuan Wang; Yun Zou; Xiaoqing Chen; Hao Li; Zhe Yin; Baocai Zhang; Yongbin Xu; Yiquan Zhang; Rulin Zhang; Xinhua Huang; Wenhui Yang; Chaoyue Xu; Tong Jiang; Qinyu Tang; Zili Zhou; Ying Ji; Yingqi Liu; Lingfei Hu; Jia Zhou; Yao Zhou; Jingjun Zhao; Ningning Liu; Guanghua Huang; Haishuang Chang; Wenxia Fang; Changbin Chen; Dongsheng Zhou
Journal:  Nat Commun       Date:  2022-06-21       Impact factor: 17.694

3.  Depletion of the Microbiota Has a Modest but Important Impact on the Fungal Burden of the Heart and Lungs during Early Systemic Candida auris Infection in Neutropenic Mice.

Authors:  Amber M Pichowicz; Steven R Torres; Fernando J Torres-Velez; Adina D Longyear; Navjot Singh; Erica Lasek-Nesselquist; Magdia De Jesus
Journal:  Microorganisms       Date:  2022-02-01

4.  Virulence of Candida auris from different clinical origins in Caenorhabditis elegans and Galleria mellonella host models.

Authors:  Ainara Hernando-Ortiz; Estibaliz Mateo; Aitzol Perez-Rodriguez; Piet W J de Groot; Guillermo Quindós; Elena Eraso
Journal:  Virulence       Date:  2021-12       Impact factor: 5.882

5.  Host-pathogen interactions upon Candida auris infection: fungal behaviour and immune response in Galleria mellonella.

Authors:  Victor Garcia-Bustos; Javier Pemán; Alba Ruiz-Gaitán; Marta Dafne Cabañero-Navalon; Ana Cabanilles-Boronat; María Fernández-Calduch; Lucía Marcilla-Barreda; Ignacio A Sigona-Giangreco; Miguel Salavert; María Ángeles Tormo-Mas; Amparo Ruiz-Saurí
Journal:  Emerg Microbes Infect       Date:  2022-12       Impact factor: 7.163

6.  Murine model of colonization with fungal pathogen Candida auris to explore skin tropism, host risk factors and therapeutic strategies.

Authors:  Xin Huang; Charlotte Hurabielle; Rebecca A Drummond; Nicolas Bouladoux; Jigar V Desai; Choon K Sim; Yasmine Belkaid; Michail S Lionakis; Julia A Segre
Journal:  Cell Host Microbe       Date:  2020-12-31       Impact factor: 21.023

7.  Candida auris Cell Wall Mannosylation Contributes to Neutrophil Evasion through Pathways Divergent from Candida albicans and Candida glabrata.

Authors:  Mark V Horton; Chad J Johnson; Robert Zarnowski; Brody D Andes; Taylor J Schoen; John F Kernien; Douglas Lowman; Michael D Kruppa; Zuchao Ma; David L Williams; Anna Huttenlocher; Jeniel E Nett
Journal:  mSphere       Date:  2021-06-23       Impact factor: 4.389

8.  Candida Cell-Surface-Specific Monoclonal Antibodies Protect Mice against Candida auris Invasive Infection.

Authors:  Jonothan Rosario-Colon; Karen Eberle; Abby Adams; Evan Courville; Hong Xin
Journal:  Int J Mol Sci       Date:  2021-06-07       Impact factor: 5.923

9.  Comparison of in vivo pathogenicity of four Candida auris clades in a neutropenic bloodstream infection murine model.

Authors:  Lajos Forgács; Andrew M Borman; Eszter Prépost; Zoltán Tóth; Gábor Kardos; Renátó Kovács; Adrien Szekely; Fruzsina Nagy; Ilona Kovacs; László Majoros
Journal:  Emerg Microbes Infect       Date:  2020-12       Impact factor: 7.163

10.  Comparative Evaluations of the Pathogenesis of Candida auris Phenotypes and Candida albicans Using Clinically Relevant Murine Models of Infections.

Authors:  Taissa Vila; Daniel Montelongo-Jauregui; Hussian Ahmed; Taanya Puthran; Ahmed S Sultan; Mary Ann Jabra-Rizk
Journal:  mSphere       Date:  2020-08-05       Impact factor: 4.389
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