| Literature DB >> 3181862 |
J M Burgunder1, D R Abernethy, B H Lauterburg.
Abstract
A 56-year-old female patient on verapamil for hypertension experienced two episodes of jaundice, pruritus and upper abdominal pain with transaminase elevated up to six-fold and alkaline phosphatase up to four-fold when inadvertently re-challenged with the drug. Liver biopsy showed marked cholestasis. Verapamil can occasionally cause mixed cytotoxic-cholestatic liver injury.Entities:
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Year: 1988 PMID： 3181862
Source DB: PubMed Journal: Hepatogastroenterology ISSN： 0172-6390