Literature DB >> 3181343

Azidothymidine-induced depression of murine hemopoietic progenitor cells.

G Bogliolo1, R Lerza, M Mencoboni, A Saviane, I Pannacciulli.   

Abstract

The toxicity of the antiviral drug 3'-azido-3'-deoxythymidine was studied in vivo on murine hemopoietic progenitor cells and peripheral blood cells. The drug induced a marked decrease of all tested populations, showing a severe toxicity on hemopoiesis.

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Year:  1988        PMID: 3181343

Source DB:  PubMed          Journal:  Exp Hematol        ISSN: 0301-472X            Impact factor:   3.084


  3 in total

1.  Inhibitory effect of 3'-azido-3'-deoxythymidine on proliferative responsiveness of CD8+ lymphocytes to interleukin-2.

Authors:  L Mercure; R Lalonde; D Phaneuf; B Brenner; M A Wainberg
Journal:  Clin Diagn Lab Immunol       Date:  1994-07

2.  Combination exposure to zidovudine plus sulfamethoxazole-trimethoprim diminishes B-lymphocyte immune responses to Pneumocystis murina infection in healthy mice.

Authors:  David J Feola; Beth A Garvy
Journal:  Clin Vaccine Immunol       Date:  2006-02

3.  Amelioration of zidovudine-induced fetal toxicity in pregnant mice.

Authors:  S R Gogu; B S Beckman; K C Agrawal
Journal:  Antimicrob Agents Chemother       Date:  1992-11       Impact factor: 5.191

  3 in total

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