Ruru Chen1, Jinjin Yu2, Michael Lipson3, Abdullah A Cheema4, Yan Chen1, Hengli Lian1, Jinhai Huang5, Colm McAlinden6. 1. School of Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, China; Key Laboratory of Vision Science, Ministry of Health P.R. China, Wenzhou, Zhejiang, China. 2. School of Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, China. 3. Department of Ophthalmology and Visual Science, University of Michigan, Northville, USA. 4. Imperial College School of Medicine, London, United Kingdom. 5. School of Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, China; Key Laboratory of Vision Science, Ministry of Health P.R. China, Wenzhou, Zhejiang, China. Electronic address: vip999vip@163.com. 6. Department of Ophthalmology, Princess of Wales Hospital, Bridgend, United Kingdom.
Abstract
PURPOSE: To compare axial length (AL) elongation in myopic children with four Orthokeratology (OrthoK) lenses and spectacles. METHODS: The medical records of 266 patients (532 eyes) who were fitted with OrthoK lenses or spectacles (control group) were reviewed. Data collection included baseline age, gender, baseline objective sphere and cylinder, baseline flat and steep corneal meridian power, corneal asphericity coefficient (Q value), AL at baseline and after 1-year, and 2-years of OrthoK or spectacle wear analyzed using analysis of repeated measures data ANOVA. Stepwise linear regressions between the changes in AL after 2 years relative to baseline parameters were calculated for the OrthoK and control groups separately. RESULTS: The baseline subject parameters for each of the four OrthoK lenses were not statistically different. Statistically significant differences between time points were found between 12- and 24- months (all P < 0.05). AL growth was slower in all OrthoK groups than in the control group (all P < 0.05). AL grew 0.081±0.034 mm per year slightly less than average with Essence compared to the Mouldway OrthoK group (P = 0.019). The coefficient of regression weakly expressed between the increases in AL over 2-years study period and baseline spherical equivalent refraction was 0.065 in Essence, 0.079 in Euclid and 0.087 in Mouldway. The coefficient of regression was also weakly between age and the increases AL over 2-years study period and baseline age in all groups. CONCLUSION: Different OrthoK lenses differ minimally in slowing axial elongation effectively in myopic children during 2-years lens wear.
PURPOSE: To compare axial length (AL) elongation in myopic children with four Orthokeratology (OrthoK) lenses and spectacles. METHODS: The medical records of 266 patients (532 eyes) who were fitted with OrthoK lenses or spectacles (control group) were reviewed. Data collection included baseline age, gender, baseline objective sphere and cylinder, baseline flat and steep corneal meridian power, corneal asphericity coefficient (Q value), AL at baseline and after 1-year, and 2-years of OrthoK or spectacle wear analyzed using analysis of repeated measures data ANOVA. Stepwise linear regressions between the changes in AL after 2 years relative to baseline parameters were calculated for the OrthoK and control groups separately. RESULTS: The baseline subject parameters for each of the four OrthoK lenses were not statistically different. Statistically significant differences between time points were found between 12- and 24- months (all P < 0.05). AL growth was slower in all OrthoK groups than in the control group (all P < 0.05). AL grew 0.081±0.034 mm per year slightly less than average with Essence compared to the Mouldway OrthoK group (P = 0.019). The coefficient of regression weakly expressed between the increases in AL over 2-years study period and baseline spherical equivalent refraction was 0.065 in Essence, 0.079 in Euclid and 0.087 in Mouldway. The coefficient of regression was also weakly between age and the increases AL over 2-years study period and baseline age in all groups. CONCLUSION: Different OrthoK lenses differ minimally in slowing axial elongation effectively in myopic children during 2-years lens wear.
Authors: Weiwei Lu; Rui Ning; Kai Diao; Yang Ding; Ruru Chen; Lei Zhou; Yan Lian; Colm McAlinden; Francis W B Sanders; Fangfang Xia; Jinhai Huang; Wanqing Jin Journal: Front Med (Lausanne) Date: 2022-04-01