Literature DB >> 31811437

The Impact of Obesity on Patient-Reported Outcomes Following Autologous Breast Reconstruction.

Jonas A Nelson1, Nikhil Sobti2, Aadit Patel2, Evan Matros2, Colleen M McCarthy2, Joseph H Dayan2, Joseph J Disa2, Peter G Cordeiro2, Babak J Mehrara2, Andrea L Pusic3, Robert J Allen2.   

Abstract

BACKGROUND: Obesity is a significant public health concern and clear risk factor for complications following breast reconstruction. To date, few have assessed patient-reported outcomes (PROs) focused on this key determinant.
OBJECTIVE: Our study aimed to investigate the impact of obesity (body mass index ≥ 30) on postoperative satisfaction and physical function utilizing the BREAST-Q in a cohort of autologous breast reconstruction patients.
METHODS: An Institutional Review Board-approved prospective investigation was conducted to evaluate PROs in patients undergoing autologous breast reconstruction from 2009 to 2017 at a tertiary academic medical center. The BREAST-Q reconstruction module was used to assess outcomes between cohorts preoperatively and at 6 months, 1 year, 2 years, and 3 years after reconstruction.
RESULTS: Overall, 404 patients underwent autologous breast reconstruction with abdominal free-tissue transfer (244 non-obese, 160 obese) and completed the BREAST-Q. Although obese patients demonstrated lower satisfaction with breasts preoperatively (p = 0.04), no significant differences were noted postoperatively (p = 0.58). However, physical well-being of the abdomen was lower in the obese cohort compared with their non-obese counterparts at long-term follow-up (3 years; p = 0.04).
CONCLUSION: Obesity significantly impacts autologous breast reconstruction patients. Although obese patients are more likely to present with dissatisfaction with breasts preoperatively, they exhibit comparable PROs overall compared with their non-obese counterparts, despite increased complications.

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Year:  2019        PMID: 31811437     DOI: 10.1245/s10434-019-08073-5

Source DB:  PubMed          Journal:  Ann Surg Oncol        ISSN: 1068-9265            Impact factor:   5.344


  47 in total

1.  Comparison of resource costs of free and conventional TRAM flap breast reconstruction.

Authors:  S S Kroll; G R Evans; G P Reece; M J Miller; G L Robb; B J Baldwin; M A Schusterman
Journal:  Plast Reconstr Surg       Date:  1996-07       Impact factor: 4.730

2.  Rise in microsurgical free-flap breast reconstruction in academic medical practices.

Authors:  Chanukya R Dasari; Sven Gunther; David H Wisner; David T Cooke; Christopher K Gold; Michael S Wong
Journal:  Ann Plast Surg       Date:  2015-05       Impact factor: 1.539

3.  The Obesity Epidemic and Bariatric Trends.

Authors:  Sanja Sljivic; Jeffrey A Gusenoff
Journal:  Clin Plast Surg       Date:  2019-01       Impact factor: 2.017

Review 4.  Impact of Obesity on Outcomes in Breast Reconstruction: A Systematic Review and Meta-Analysis.

Authors:  Adriana C Panayi; Riaz A Agha; Brady A Sieber; Dennis P Orgill
Journal:  J Reconstr Microsurg       Date:  2018-03-06       Impact factor: 2.873

5.  Obesity, body size, and risk of postmenopausal breast cancer: the Women's Health Initiative (United States).

Authors:  Libby M Morimoto; Emily White; Z Chen; Rowan T Chlebowski; Jennifer Hays; Lewis Kuller; Ana Marie Lopez; JoAnn Manson; Karen L Margolis; Paola C Muti; Marcia L Stefanick; Anne McTiernan
Journal:  Cancer Causes Control       Date:  2002-10       Impact factor: 2.506

6.  The global obesity pandemic: shaped by global drivers and local environments.

Authors:  Boyd A Swinburn; Gary Sacks; Kevin D Hall; Klim McPherson; Diane T Finegood; Marjory L Moodie; Steven L Gortmaker
Journal:  Lancet       Date:  2011-08-27       Impact factor: 79.321

7.  Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010.

Authors:  Katherine M Flegal; Margaret D Carroll; Brian K Kit; Cynthia L Ogden
Journal:  JAMA       Date:  2012-01-17       Impact factor: 56.272

8.  Cost-effectiveness analysis of implants versus autologous perforator flaps using the BREAST-Q.

Authors:  Evan Matros; Claudia R Albornoz; Shantanu N Razdan; Babak J Mehrara; Sheina A Macadam; Teresa Ro; Colleen M McCarthy; Joseph J Disa; Peter G Cordeiro; Andrea L Pusic
Journal:  Plast Reconstr Surg       Date:  2015-04       Impact factor: 4.730

9.  Patient Satisfaction and Quality of Life in DIEAP Flap versus Implant Breast Reconstruction.

Authors:  Rossella Sgarzani; Luca Negosanti; Paolo Giovanni Morselli; Veronica Vietti Michelina; Luigi Maria Lapalorcia; Riccardo Cipriani
Journal:  Surg Res Pract       Date:  2015-11-16

10.  Sensation of the autologous reconstructed breast improves quality of life: a pilot study.

Authors:  Anouk J M Cornelissen; Jop Beugels; Sander M J van Kuijk; Esther M Heuts; Shai M Rozen; Aldona J Spiegel; René R W J van der Hulst; Stefania M H Tuinder
Journal:  Breast Cancer Res Treat       Date:  2017-10-25       Impact factor: 4.872

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  2 in total

1.  Long-Term Patient Satisfaction and Quality of Life Following Breast Reconstruction Using the BREAST-Q: A Prospective Cohort Study.

Authors:  Makoto Shiraishi; Yoshihiro Sowa; Itaru Tsuge; Takuya Kodama; Naoki Inafuku; Naoki Morimoto
Journal:  Front Oncol       Date:  2022-05-23       Impact factor: 5.738

Review 2.  Submuscular and Pre-Pectoral ADM Assisted Immediate Breast Reconstruction: A Literature Review.

Authors:  Roberto Cuomo
Journal:  Medicina (Kaunas)       Date:  2020-05-26       Impact factor: 2.430

  2 in total

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