Literature DB >> 3181138

Isolation and structural analysis of a peptide containing the novel tyrosyl-glucose linkage in glycogenin.

C Smythe1, F B Caudwell, M Ferguson, P Cohen.   

Abstract

The glucosylation site on glycogenin, the protein primer required for de novo glycogen synthesis, has been identified. The glucose is attached at position C1 in a glycosidic linkage with a unique tyrosine, and the sequence surrounding this residue was found to be: His-Leu-Pro-Phe-Ile-Tyr-Asn-Leu-Ser-Ser-Ile-Ser-Ile-Tyr(Glc)-Ser-Tyr-Leu -Pro- Ala-Phe-Lys. The same tyrosine residue is glycosylated whether glycogenin is isolated as a complex with the catalytic subunit of glycogen synthase, or covalently attached to glycogen. The possibility that insulin and growth factors may enhance glycogen synthesis via stimulation of the priming reaction is discussed.

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Year:  1988        PMID： 3181138      PMCID： PMC457056          DOI： 10.1002/j.1460-2075.1988.tb03121.x

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   11.598


  13 in total

1.  Observations on the quantitation of the phosphate content of peptides by fast-atom bombardment mass spectrometry.

Authors:  L Poulter; S G Ang; D H Williams; P Cohen
Journal:  Biochim Biophys Acta       Date:  1987-07-29

2.  The subcellular distribution of terminal N-acetylglucosamine moieties. Localization of a novel protein-saccharide linkage, O-linked GlcNAc.

Authors:  G D Holt; G W Hart
Journal:  J Biol Chem       Date:  1986-06-15       Impact factor: 5.157

3.  The purification and properties of rabbit skeletal muscle glycogen synthase.

Authors:  H G Nimmo; C G Proud; P Cohen
Journal:  Eur J Biochem       Date:  1976-09

4.  A precursor of glycogen biosynthesis: alpha-1,4-glucan-protein.

Authors:  C R Krisman; R Barengo
Journal:  Eur J Biochem       Date:  1975-03-03

5.  Glycogen synthase kinase-2 and phosphorylase kinase are the same enzyme.

Authors:  N Embi; D B Rylatt; P Cohen
Journal:  Eur J Biochem       Date:  1979-10-15

6.  Genome-linked proteins of viruses.

Authors:  E Wimmer
Journal:  Cell       Date:  1982-02       Impact factor: 41.582

7.  Kinetics of iodination. IV. A comparison of the kinetics of iodination of L-tyrosine and some derivatives.

Authors:  W E Mayberry; J E Rall; D Bertoli
Journal:  Biochemistry       Date:  1965-12       Impact factor: 3.162

8.  The protein phosphatases involved in cellular regulation. Primary structure of inhibitor-2 from rabbit skeletal muscle.

Authors:  C F Holmes; D G Campbell; F B Caudwell; A Aitken; P Cohen
Journal:  Eur J Biochem       Date:  1986-02-17

9.  Epidermal growth factor stimulates glycogen synthase activity in cultured cells.

Authors:  C P Chan; E G Krebs
Journal:  Proc Natl Acad Sci U S A       Date:  1985-07       Impact factor: 11.205

10.  A 42,000-Da protein in rabbit tissues and in a glycogen synthase preparation cross-reacts with antibodies to glycogenin.

Authors:  I R Rodriguez; S J Fliesler
Journal:  Arch Biochem Biophys       Date:  1988-02-01       Impact factor: 4.013
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  22 in total

1.  Molecular cloning and developmental expression of rat glycogenin in cardiac tissue.

Authors:  B J Pak; S J Sangaralingham; S C Pang
Journal:  Mol Cell Biochem       Date:  1999-04       Impact factor: 3.396

2.  Two glycogen synthase activities associated with proteoglycogen in retina.

Authors:  J A Curtino; E R Lacoste
Journal:  Neurochem Res       Date:  2000-01       Impact factor: 3.996

3.  Conformational plasticity of glycogenin and its maltosaccharide substrate during glycogen biogenesis.

Authors:  Apirat Chaikuad; D Sean Froese; Georgina Berridge; Frank von Delft; Udo Oppermann; Wyatt W Yue
Journal:  Proc Natl Acad Sci U S A       Date:  2011-12-12       Impact factor: 11.205

4.  Direct detection of glycogenin reaction products during glycogen initiation.

Authors:  Thomas D Hurley; Chad Walls; John R Bennett; Peter J Roach; Mu Wang
Journal:  Biochem Biophys Res Commun       Date:  2006-07-28       Impact factor: 3.575

5.  Site-specific characterization of threonine, serine, and tyrosine glycosylations of amyloid precursor protein/amyloid beta-peptides in human cerebrospinal fluid.

Authors:  Adnan Halim; Gunnar Brinkmalm; Ulla Rüetschi; Ann Westman-Brinkmalm; Erik Portelius; Henrik Zetterberg; Kaj Blennow; Göran Larson; Jonas Nilsson
Journal:  Proc Natl Acad Sci U S A       Date:  2011-06-28       Impact factor: 11.205

6.  Interaction between glycogenin and glycogen synthase.

Authors:  Alexander V Skurat; Amy D Dietrich; Peter J Roach
Journal:  Arch Biochem Biophys       Date:  2006-10-10       Impact factor: 4.013

7.  The distribution of GYR- and YLP-like motifs in Drosophila suggests a general role in cuticle assembly and other protein-protein interactions.

Authors:  R Scott Cornman
Journal:  PLoS One       Date:  2010-09-02       Impact factor: 3.240

8.  A glycogen precursor associated with membrane in retina.

Authors:  E R Lacoste; M C Miozzo; J A Curtino
Journal:  Biochem J       Date:  1990-05-01       Impact factor: 3.857

9.  Cyclic beta-(1,2)-glucan synthesis in Rhizobiaceae: roles of the 319-kilodalton protein intermediate.

Authors:  O A Castro; A Zorreguieta; V Ielmini; G Vega; L Ielpi
Journal:  J Bacteriol       Date:  1996-10       Impact factor: 3.490

10.  Requirement of the self-glucosylating initiator proteins Glg1p and Glg2p for glycogen accumulation in Saccharomyces cerevisiae.

Authors:  C Cheng; J Mu; I Farkas; D Huang; M G Goebl; P J Roach
Journal:  Mol Cell Biol       Date:  1995-12       Impact factor: 4.272
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