Domenico Paparella1, Khalil Fattouch2, Marco Moscarelli3, Giuseppe Santarpino4, Giuseppe Nasso3, Pietro Guida5, Vito Margari6, Luigi Martinelli7, Roberto Coppola7, Alberto Albertini8, Mauro Del Giglio9, Renato Gregorini10, Giuseppe Speziale11. 1. Santa Maria Hospital, Department of Cardiac Surgery, GVM Care & Research, Bari, Italy; Department of Emergency and Organ Transplant, University of Bari Aldo Moro, Italy. Electronic address: domenico.paparella@uniba.it. 2. Maria Eleonora Hospital, Department of Cardiac Surgery, GVM Care & Research, Palermo, Italy. 3. Anthea Hospital, Department of Cardiac Surgery, GVM Care & Research, Bari, Italy. 4. Città di Lecce Hospital, Department of Cardiac Surgery, GVM Care & Research, Lecce, Italy; Klinikum Nürnberg, Department of Cardiac Surgery, Paracelsus Medical University, Nuremberg, Germany. 5. Maugeri Foundation, Cassano delle Murge, Bari, Italy. 6. Santa Maria Hospital, Department of Cardiac Surgery, GVM Care & Research, Bari, Italy. 7. ICLAS, Department of Cardiac Surgery, GVM Care & Research, Rapallo, Italy. 8. Maria Cecilia Hospital, Department of Cardiac Surgery, GVM Care & Research, Cotignola, Italy. 9. Villa Torri Hospital, Department of Cardiovascular Surgery, GVM Care & Research, Bologna, Italy. 10. Città di Lecce Hospital, Department of Cardiac Surgery, GVM Care & Research, Lecce, Italy. 11. Anthea Hospital, Department of Cardiac Surgery, GVM Care & Research, Bari, Italy; Maria Cecilia Hospital, Department of Cardiac Surgery, GVM Care & Research, Cotignola, Italy.
Abstract
BACKGROUND: Mitral valve surgery (MVS) is evolving. Compared to standard sternotomy (S-MVS), minimally invasive method (Mini-MVS) has been increasingly adopted in the last years with encouraging results for both repairs and replacements. We evaluated trends of surgical approaches and operative outcomes in a multicenter study involving 10 cardiac surgical centers in Italy. METHODS: Patients who received isolated mitral valve surgery, including only a concomitant tricuspid valve repair, from January 2011 up to December 2017. Minimally invasive approach (right anterior mini-thoracotomy) and standard sternotomy was performed in 2602 and 1947 patients, respectively. Stratifying by surgery, 1493 patients per group were paired using a propensity matching procedure. RESULTS: The minimally invasive approach has been progressively more frequent over the years (from 27.5% in 2011 to 71.7% in 2017). Compared to S-MVS, Mini-MVS patients were younger with less preoperative comorbidities and less frequently operated for valve replacement or in association with tricuspid repair. The 30-day mortality was lower in the Mini-MVS (overall 1.2% vs 2.7%; p < 0.001) as well as the incidence of most postoperative complications. Subjects paired by propensity score had similar 30-day mortality (1.9% vs 1.8%, p = 0.786) but lower blood transfusion and permanent pace-maker insertion. Cardiopulmonary bypass and cross-clamp time, initially longer in the Mini-MVS patients, became shorter in recent years for the minimally invasive approach. CONCLUSIONS: In a large multi-institutional recent cohort, minimally invasive mitral valve surgery has drastically increased being the preferred technique and appears to be safe with procedural duration shorter than the beginning.
BACKGROUND: Mitral valve surgery (MVS) is evolving. Compared to standard sternotomy (S-MVS), minimally invasive method (Mini-MVS) has been increasingly adopted in the last years with encouraging results for both repairs and replacements. We evaluated trends of surgical approaches and operative outcomes in a multicenter study involving 10 cardiac surgical centers in Italy. METHODS:Patients who received isolated mitral valve surgery, including only a concomitant tricuspid valve repair, from January 2011 up to December 2017. Minimally invasive approach (right anterior mini-thoracotomy) and standard sternotomy was performed in 2602 and 1947 patients, respectively. Stratifying by surgery, 1493 patients per group were paired using a propensity matching procedure. RESULTS: The minimally invasive approach has been progressively more frequent over the years (from 27.5% in 2011 to 71.7% in 2017). Compared to S-MVS, Mini-MVS patients were younger with less preoperative comorbidities and less frequently operated for valve replacement or in association with tricuspid repair. The 30-day mortality was lower in the Mini-MVS (overall 1.2% vs 2.7%; p < 0.001) as well as the incidence of most postoperative complications. Subjects paired by propensity score had similar 30-day mortality (1.9% vs 1.8%, p = 0.786) but lower blood transfusion and permanent pace-maker insertion. Cardiopulmonary bypass and cross-clamp time, initially longer in the Mini-MVS patients, became shorter in recent years for the minimally invasive approach. CONCLUSIONS: In a large multi-institutional recent cohort, minimally invasive mitral valve surgery has drastically increased being the preferred technique and appears to be safe with procedural duration shorter than the beginning.
Authors: Akram Kawsara; Fahad Alqahtani; Vuyisile T Nkomo; Mackram F Eleid; Sorin V Pislaru; Charanjit S Rihal; Rick A Nishimura; Hartzell V Schaff; Juan A Crestanello; Mohamad Alkhouli Journal: J Am Heart Assoc Date: 2021-01-05 Impact factor: 5.501