Literature DB >> 31808142

A 3-year prospective clinical and patient-centered trial on subepithelial connective tissue graft with or without enamel matrix derivative in Class I-II Miller recessions.

Faustino Mercado1,2, Stephen Hamlet1,3, Sašo Ivanovski2.   

Abstract

BACKGROUND AND
OBJECTIVE: The study compared clinical and patient-centered outcomes of subepithelial connective tissue graft (CTG) with and without enamel matrix derivative (EMD) in the treatment of Class I-II Miller periodontal recession defects.
MATERIAL AND METHODS: This prospective clinical study evaluated 80 patients over a 3 years follow-up in a private periodontal practice. A total of 144 maxillary and mandibular anterior teeth were divided into two groups: group 1 (CTG with EMD-80 teeth) and group 2 (CTG only-64 teeth). Recession (REC), keratinized tissue (KT) width, % root overage, patient-centered outcomes, and pain visual analog scale (P-VAS) were compared between the two groups.
RESULTS: At 3 years follow-up at a patient level, statistically significant changes in REC were achieved in both group 1 (4.65 ± 1.84 to 0.39 ± 0.19 mm) and group 2 (4.43 ± 1.11 to 0.92 ± 0.43 mm). Complete root coverage (CRC) was achieved in 66.4% of group 1 and 50.1% of group 2. At both patient and tooth level, the 3-year outcomes were superior for group 1 compared with group 2 in terms of % root coverage, REC, and KT width. Clinical attachment loss (CAL) was reduced in group 1 compared with group 2 at the tooth level analysis only (<.01). Significantly less pain was reported using the pain visual analog Scale (P < .001) at the two weeks follow-up post-surgery in group 1.
CONCLUSIONS: Addition of EMD results in improved root coverage outcomes and higher amounts of keratinized tissue width 36 months after treatment of multiple adjacent recessions on maxillary and mandibular anterior teeth. The adjunctive use of EMD also resulted in significantly reduced pain 14 days after the surgery.
© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  enamel matrix proteins; gingival recession; pain level; periodontal plastic surgical flaps

Year:  2019        PMID: 31808142     DOI: 10.1111/jre.12715

Source DB:  PubMed          Journal:  J Periodontal Res        ISSN: 0022-3484            Impact factor:   4.419


  7 in total

Review 1.  Does enamel matrix derivative application provide additional clinical benefits in the treatment of maxillary Miller class I and II gingival recession? A systematic review and meta-analysis.

Authors:  Jonathan Meza Mauricio; Camila Pinheiro Furquim; Willy Bustillos-Torrez; David Soto-Peñaloza; David Peñarrocha-Oltra; Belen Retamal-Valdes; Marcelo Faveri
Journal:  Clin Oral Investig       Date:  2021-01-21       Impact factor: 3.573

2.  Tunnel technique with enamel matrix derivative in addition to subepithelial connective tissue graft compared with connective tissue graft alone for the treatment of multiple gingival recessions: a randomized clinical trial.

Authors:  Bartłomiej Górski; Renata Górska; Joanna Wysokińska-Miszczuk; Tomasz Kaczyński
Journal:  Clin Oral Investig       Date:  2020-05-07       Impact factor: 3.573

Review 3.  Regenerative Potential of Enamel Matrix Protein Derivative and Acellular Dermal Matrix for Gingival Recession: A Systematic Review and Meta-Analysis.

Authors:  Muhammad Saad Shaikh; Mohid Abrar Lone; Hesham Matabdin; Muneeb Ahmed Lone; Azeem Hussain Soomro; Muhammad Sohail Zafar
Journal:  Proteomes       Date:  2021-02-25

4.  Modified coronally advanced tunnel technique with enamel matrix derivative in addition to subepithelial connective tissue graft compared with connective tissue graft alone for the treatment of multiple gingival recessions: prognostic parameters for clinical treatment outcomes.

Authors:  Bartłomiej Górski; Renata Górska; Marcin Szerszeń; Tomasz Kaczyński
Journal:  Clin Oral Investig       Date:  2021-07-04       Impact factor: 3.606

5.  Recession coverage using the modified coronally advanced tunnel and connective tissue graft with or without enamel matrix derivative: 5-year results of a randomised clinical trial.

Authors:  A Stähli; H Y Duong; J C Imber; A Roccuzzo; G E Salvi; C Katsaros; C A Ramseier; A Sculean
Journal:  Clin Oral Investig       Date:  2022-08-25       Impact factor: 3.606

6.  Effect of Root Surface Biomodification on Multiple Recession Coverage with Modified Coronally Advanced Tunnel Technique and Subepithelial Connective Tissue Graft: A Retrospective Analysis.

Authors:  Bartłomiej Górski; Marcin Szerszeń
Journal:  Gels       Date:  2022-01-04

Review 7.  Root coverage stability: A systematic overview of controlled clinical trials with at least 5 years of follow-up.

Authors:  Kristina Bertl; Loukia M Spineli; Khalid Mohandis; Andreas Stavropoulos
Journal:  Clin Exp Dent Res       Date:  2021-02-09
  7 in total

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