Literature DB >> 31807357

In vitro bioaccessibility of added folic acid in commercially available baby foods formulated with milk and milk products.

Mustafa Yaman1, Ömer Faruk Mızrak1, Jale Çatak1, Hafsa Sena Sargın1.   

Abstract

Milk contains a certain amount of folate binding proteins. The binding capacity varies in acidic conditions and affects the bioavailability of folic acid. Folic acid is commonly added into baby foods to ensure adequate intake of infants. The aim of this study was to determine the bioaccessibility of added folic acid in baby foods formulated with milk and milk products under different gastric pH values by an in vitro digestive system. The bioaccessibility of folic acid ranged between 56-71 and 35-49% in infant formula samples, between 59-78 and 31-67% in cereal-based baby foods, and between 42-67 and 38-57% in follow-on baby milk at gastric pH 1.5 and pH 4, respectively. Our results demonstrate that the bioaccesibility of folic acid that is added to baby food is affected by gastric pH. Therefore, it was observed that the bioaccesibility of folic acid was lower in the higher gastric pH. © The Korean Society of Food Science and Technology 2019.

Entities:  

Keywords:  Baby foods; Bioaccessibility; Folate binding protein; Folic acid; Milk

Year:  2019        PMID: 31807357      PMCID: PMC6859173          DOI: 10.1007/s10068-019-00625-5

Source DB:  PubMed          Journal:  Food Sci Biotechnol        ISSN: 1226-7708            Impact factor:   2.391


  26 in total

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4.  A standardised static in vitro digestion method suitable for food - an international consensus.

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Journal:  Food Funct       Date:  2014-05-07       Impact factor: 5.396

5.  Bioavailability of folic acid from fortified pasteurised and UHT-treated milk in humans.

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6.  Detection of a milk factor that facilitates folate uptake by intestinal cells.

Authors:  N Colman; N Hettiarachchy; V Herbert
Journal:  Science       Date:  1981-03-27       Impact factor: 47.728

7.  Folic acid and 5-methyltetrahydrofolate in fortified milk are bioaccessible as determined in a dynamic in vitro gastrointestinal model.

Authors:  Miriam Verwei; Karin Arkbåge; Robert Havenaar; Henk van den Berg; Cornelia Witthöft; Gertjan Schaafsma
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8.  Bioaccessibility of folic acid and (6S)-5-methyltetrahydrofolate decreases after the addition of folate-binding protein to yogurt as studied in a dynamic in vitro gastrointestinal model.

Authors:  Karin Arkbåge; Miriam Verwei; Robert Havenaar; Cornelia Witthöft
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9.  The binding of folic acid and 5-methyltetrahydrofolate to folate-binding proteins during gastric passage differs in a dynamic in vitro gastrointestinal model.

Authors:  Miriam Verwei; Karin Arkbåge; Hans Mocking; Robert Havenaar; John Groten
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10.  Influence of goat's-milk folate-binding protein on transport of 5-methyltetrahydrofolate in neonatal-goat small intestinal brush-border-membrane vesicles.

Authors:  D N Salter; P Blakeborough
Journal:  Br J Nutr       Date:  1988-05       Impact factor: 3.718

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  2 in total

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Authors:  Cristine Couto Almeida; Bianca Figueiredo Mendonça Pereira; Katia Christina Leandro; Marion Pereira Costa; Bernardete Ferraz Spisso; Carlos Adam Conte-Junior
Journal:  Int J Food Sci       Date:  2021-05-14

2.  In Vitro Bioaccessibility of Bioactive Compounds from Rosehip-Enriched Corn Extrudates.

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