Literature DB >> 31805341

Recent sulfur mustard attacks in Middle East and experience of health professionals.

Sermet Sezigen1, Levent Kenar2.   

Abstract

Sulfur mustard (SM) is a vesicant chemical warfare agent which affects ocular, respiratory, and cutaneous system. In this study, we aimed to share recent experiences on medical management of chemical casualties that were exposed to SM in Middle East. We reported medical management of 17 contaminated patients. After the evacuation from the hot zone, all chemical casualties should be transferred to the designated intensive care units. After detailed medical decontamination and stabilization, biological samples should be collected from all chemical casualties as soon as possible for the verification of the exposure. Medical history and existing symptoms reveal the clinical diagnosis of SM exposure. Medical management of SM casualties should focus on "good nursing care" including treatment of pain and itching, fluid and electrolyte replacement therapy, respiration and nutrition support. Despite of improved clinical skills, treatment of SM lesions is still non-specific which aims to relieve symptoms and to prevent infections. Existing diagnostic capabilities and treatment approaches could be improved by sharing recent clinical experiences on medical management of SM casualties where there are still important major gaps.
Copyright © 2019 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  CBRN; Chemical casualties; Chemical terrorism; Decontamination; Sulfur mustard

Mesh:

Substances:

Year:  2019        PMID: 31805341     DOI: 10.1016/j.toxlet.2019.12.001

Source DB:  PubMed          Journal:  Toxicol Lett        ISSN: 0378-4274            Impact factor:   4.372


  5 in total

1.  Glutathione conjugates of the mercapturic acid pathway and guanine adduct as biomarkers of exposure to CEES, a sulfur mustard analog.

Authors:  Marie Roser; David Béal; Camille Eldin; Leslie Gudimard; Fanny Caffin; Fanny Gros-Désormeaux; Daniel Léonço; François Fenaille; Christophe Junot; Christophe Piérard; Thierry Douki
Journal:  Anal Bioanal Chem       Date:  2021-01-07       Impact factor: 4.142

2.  A novel sulfur mustard (HD) vapor inhalation exposure model of pulmonary toxicity for the efficacy evaluation of candidate medical countermeasures.

Authors:  Mark R Perry; Matthew Neal; Roger Hawks; David Pressburger; Jan Satola; Cheryl Triplett; Beth Reed; Meredith Andrews; Jill A Harvilchuck; Michael S Nealy; Gennady E Platoff; David T Yeung
Journal:  Inhal Toxicol       Date:  2021-08-15       Impact factor: 2.724

3.  Supporting discovery and development of medical countermeasures for chemical injury to eye and skin.

Authors:  Houmam Araj; Hung Tseng; David T Yeung
Journal:  Exp Eye Res       Date:  2022-06-15       Impact factor: 3.770

4.  Highly stable peptide adducts from hard keratins as biomarkers to verify local sulfur mustard exposure of hair by high-resolution mass spectrometry.

Authors:  Wolfgang Schmeißer; Markus Siegert; Horst Thiermann; Theo Rein; Harald John
Journal:  Arch Toxicol       Date:  2022-05-16       Impact factor: 6.168

5.  Exploring pre-hospital healthcare workers' readiness for chemical, biological, radiological, and nuclear threats in the State of Qatar: A cross-sectional study.

Authors:  Hassan Farhat; Guillaume Alinier; Padarath Gangaram; Kawther El Aifa; Mohamed Chaker Khenissi; Sonia Bounouh; Moncef Khadhraoui; Imed Gargouri; James Laughton
Journal:  Health Sci Rep       Date:  2022-08-30
  5 in total

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