Literature DB >> 31805191

Amplification and overexpression of E2 ubiquitin conjugase UBE2T promotes homologous recombination in multiple myeloma.

David A Alagpulinsa1,2,3,4, Subodh Kumar1,2, Srikanth Talluri1,2, Purushothama Nanjappa1,2, Leutz Buon1, Chandraditya Chakraborty1, Mehmet K Samur1,2,3, Raphael Szalat1,2,3, Masood A Shammas1,2, Nikhil C Munshi1,2,3.   

Abstract

Entities:  

Year:  2019        PMID： 31805191      PMCID： PMC6963244          DOI： 10.1182/bloodadvances.2019000181

Source DB:  PubMed          Journal:  Blood Adv        ISSN： 2473-9529


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  24 in total

1.  XRCC3 promotes homology-directed repair of DNA damage in mammalian cells.

Authors:  A J Pierce; R D Johnson; L H Thompson; M Jasin
Journal:  Genes Dev       Date:  1999-10-15       Impact factor: 11.361

2.  S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51.

Authors:  Toshiyasu Taniguchi; Irene Garcia-Higuera; Paul R Andreassen; Richard C Gregory; Markus Grompe; Alan D D'Andrea
Journal:  Blood       Date:  2002-10-01       Impact factor: 22.113

3.  Inhibition of homologous recombination in human cells by targeting RAD51 recombinase.

Authors:  Fei Huang; Olga M Mazina; Isaac J Zentner; Simon Cocklin; Alexander V Mazin
Journal:  J Med Chem       Date:  2012-03-19       Impact factor: 7.446

Review 4.  Multiple myeloma: evolving genetic events and host interactions.

Authors:  W Michael Kuehl; P Leif Bergsagel
Journal:  Nat Rev Cancer       Date:  2002-03       Impact factor: 60.716

5.  Genomic instability in multiple myeloma: evidence for jumping segmental duplications of chromosome arm 1q.

Authors:  Jeffrey R Sawyer; Guido Tricot; Janet L Lukacs; Regina Lichti Binz; Erming Tian; Bart Barlogie; John Shaughnessy
Journal:  Genes Chromosomes Cancer       Date:  2005-01       Impact factor: 5.006

Review 6.  Role of the human RAD51 protein in homologous recombination and double-stranded-break repair.

Authors:  P Baumann; S C West
Journal:  Trends Biochem Sci       Date:  1998-07       Impact factor: 13.807

7.  Genomic patterns of progression in smoldering multiple myeloma.

Authors:  Niccolò Bolli; Francesco Maura; Stephane Minvielle; Dominik Gloznik; Raphael Szalat; Anthony Fullam; Inigo Martincorena; Kevin J Dawson; Mehmet Kemal Samur; Jorge Zamora; Patrick Tarpey; Helen Davies; Mariateresa Fulciniti; Masood A Shammas; Yu Tzu Tai; Florence Magrangeas; Philippe Moreau; Paolo Corradini; Kenneth Anderson; Ludmil Alexandrov; David C Wedge; Herve Avet-Loiseau; Peter Campbell; Nikhil Munshi
Journal:  Nat Commun       Date:  2018-08-22       Impact factor: 14.919

8.  High expression of UBE2T predicts poor prognosis and survival in multiple myeloma.

Authors:  Weilong Zhang; Ye Zhang; Zuozhen Yang; Xiaoni Liu; Ping Yang; Jing Wang; Kai Hu; Xue He; Xiuru Zhang; Hongmei Jing
Journal:  Cancer Gene Ther       Date:  2019-01-09       Impact factor: 5.987

9.  Targeting homologous recombination and telomerase in Barrett's adenocarcinoma: impact on telomere maintenance, genomic instability and tumor growth.

Authors:  R Lu; J Pal; L Buon; P Nanjappa; J Shi; M Fulciniti; Y-T Tai; L Guo; M Yu; S Gryaznov; N C Munshi; M A Shammas
Journal:  Oncogene       Date:  2013-04-22       Impact factor: 9.867

10.  Heterogeneity of genomic evolution and mutational profiles in multiple myeloma.

Authors:  Niccolo Bolli; Hervé Avet-Loiseau; David C Wedge; Peter Van Loo; Ludmil B Alexandrov; Inigo Martincorena; Kevin J Dawson; Francesco Iorio; Serena Nik-Zainal; Graham R Bignell; Jonathan W Hinton; Yilong Li; Jose M C Tubio; Stuart McLaren; Sarah O' Meara; Adam P Butler; Jon W Teague; Laura Mudie; Elizabeth Anderson; Naim Rashid; Yu-Tzu Tai; Masood A Shammas; Adam S Sperling; Mariateresa Fulciniti; Paul G Richardson; Giovanni Parmigiani; Florence Magrangeas; Stephane Minvielle; Philippe Moreau; Michel Attal; Thierry Facon; P Andrew Futreal; Kenneth C Anderson; Peter J Campbell; Nikhil C Munshi
Journal:  Nat Commun       Date:  2014       Impact factor: 14.919
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  5 in total

1.  UBE2T is upregulated, predicts poor prognosis, and promotes cell proliferation and invasion by promoting epithelial-mesenchymal transition via inhibiting autophagy in an AKT/mTOR dependent manner in ovarian cancer.

Authors:  Wei Huang; Hongyan Huang; Yuzhen Xiao; Lei Wang; Tingting Zhang; Xiaoling Fang; Xiaomeng Xia
Journal:  Cell Cycle       Date:  2022-02-07       Impact factor: 5.173

2.  Integrated genomics and comprehensive validation reveal drivers of genomic evolution in esophageal adenocarcinoma.

Authors:  Subodh Kumar; Leutz Buon; Srikanth Talluri; Marco Roncador; Chengcheng Liao; Jiangning Zhao; Jialan Shi; Chandraditya Chakraborty; Gabriel Gonzalez; Yu-Tzu Tai; Rao Prabhala; Mehmet K Samur; Nikhil C Munshi; Masood A Shammas
Journal:  Commun Biol       Date:  2021-05-24

3.  A novel UBE2T inhibitor suppresses Wnt/β-catenin signaling hyperactivation and gastric cancer progression by blocking RACK1 ubiquitination.

Authors:  Zeyuan Yu; Xiangyan Jiang; Long Qin; Haixiao Deng; Jianli Wang; Wen Ren; Hongbin Li; Lei Zhao; Huanxiang Liu; Hong Yan; Wengui Shi; Qi Wang; Changjiang Luo; Bo Long; Huinian Zhou; Hui Sun; Zuoyi Jiao
Journal:  Oncogene       Date:  2020-12-15       Impact factor: 9.867

4.  Identification of Biomarkers Based on Bioinformatics Analysis: The Expression of Ubiquitin-Conjugating Enzyme E2T (UBE2T) in the Carcinogenesis and Progression of Hepatocellular Carcinoma.

Authors:  Xuemiao Zhao; Wei Weng; Miao Jin; Sunjian Li; Qingwei Chen; Bingrong Li; Zhou Zhou; Chuanqiang Lan; Yunjun Yang
Journal:  Med Sci Monit       Date:  2021-03-04

Review 5.  The Molecular Basis of Ubiquitin-Conjugating Enzymes (E2s) as a Potential Target for Cancer Therapy.

Authors:  Xiaodi Du; Hongyu Song; Nengxing Shen; Ruiqi Hua; Guangyou Yang
Journal:  Int J Mol Sci       Date:  2021-03-26       Impact factor: 5.923
  5 in total

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