Potential of Tribological Properties of Metal Nanomaterials in Biomedical Applications.

Metallic nanomaterials show tremendous applications in biomedical devices due to compatible integration into the most of the biological systems as they are nano- structured. Metallic nanomaterials are capable of mimicking all the three major antioxidant enzymes such as catalase (CAT), peroxidase and oxidase, to control the level of reactive oxygen species (ROS) inside the cell as an alternative strategy over conventional one which has biological toxicity and have several adverse effects, if accumulation takes places during the treatment. This anti-oxidant property of metallic nanomaterials demonstrates as a promising candidate for its biomedical application in disease conditions where the excessive level of ROS causes damage to DNA, lipids and protein in several conditions such as diabetes, cancer and neurodegenerative diseases. Tribology is the study of interacting surfaces in motion and the measurement of properties such as friction, wear-tear and abrasion. While designing nano-scale biomedical devices, the consideration of tribology is particularly important because the high surface area ratio enhances problems with friction and wear-tear which can further affects its function as well as longevity.