Literature DB >> 31800689

Admission NT-ProBNP in Myocardial Infarction: an Alert Sign?

Luís Beck da Silva1.   

Abstract

Entities:  

Year:  2019        PMID: 31800689      PMCID: PMC7021265          DOI: 10.36660/abc.20190685

Source DB:  PubMed          Journal:  Arq Bras Cardiol        ISSN: 0066-782X            Impact factor:   2.000


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This issue of Arquivos Brasileiros de Cardiologia brings a paper entitled “The Usefulness of Admission Plasma NT-pro BNP Level to Predict Left Ventricular Aneurysm Formation after Acute ST-Segment Elevation Myocardial Infarction”.[1] The authors bring a cohort of 1,519 post-acute ST-segment elevation myocardial infarction (STEMI) who were followed-uP for at least six months. Despite its observational and retrograde design, the authors were straightforward in looking for predictive variables that could foresee the occurrence of left ventricular aneurysms (LVA). Among other major clinical aspects such as previous coronary artery bypass graft, post-MI heart failure, younger age, smoking and no-reflow phenomenon; authors highlighted the importance of high NT-proBNP at admission as a predictor of LVA formation after acute STEMI. I would probably highlight one weakness and a potentially positive aspect of their work. The weakness is that a LVA will never be diagnosed by a NT-Pro-BNP level and will always be found, confirmed and/or followed by an image test (Echo, CMR, etc.). NT-ProBNP usually and reliably identifies patients who are sicker or more congested, either in acute,[2] or in chronic heart failure,[3] or even without heart failure.[4] The potentially positive one was, interestingly, what the authors have considered their limitation: that the NT-ProBNP values have been collected at admission. Having a high natriuretic peptide level at the admission of a STEMI patient could be a predictive variable of a clinical event, such as LVA formation, in six months. It was there, on the “Limitations” section, the best and most clinically relevant information.
  4 in total

1.  B-type natriuretic peptide: a novel early blood marker of acute myocardial infarction in patients with chest pain and no ST-segment elevation.

Authors:  Roberto Bassan; Alfredo Potsch; Alan Maisel; Bernardo Tura; Humberto Villacorta; Mônica Viegas Nogueira; Augusta Campos; Roberto Gamarski; Antonio Cláudio Masetto; Marco Aurélio Moutinho
Journal:  Eur Heart J       Date:  2004-12-01       Impact factor: 29.983

2.  BNP-guided therapy for chronic heart failure: anything more than just an attractive concept?

Authors:  Martin R Cowie
Journal:  Eur Heart J       Date:  2014-04-08       Impact factor: 29.983

3.  Similar BNP and Mortality Association in Patients With and Without Heart Failure: Any Increase Matters.

Authors:  Nicolas Vodovar; Damien Logeart
Journal:  J Am Coll Cardiol       Date:  2018-05-15       Impact factor: 24.094

4.  The Usefulness of Admission Plasma NT-pro BNP Level to Predict Left Ventricular Aneurysm Formation after Acute ST-Segment Elevation Myocardial Infarction.

Authors:  Savas Celebi; Ozlem Ozcan Celebi; Serkan Cetin; Hande Ozcan Cetin; Mujgan Tek; Serkan Gokaslan; Basri Amasyali; Berkten Berkalp; Erdem Diker; Sinan Aydogdu
Journal:  Arq Bras Cardiol       Date:  2019-12       Impact factor: 2.000

  4 in total

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