Literature DB >> 31795785

Current and emerging trends in point-of-care urinalysis tests.

Rongwei Lei1, Rannon Huo1, Chandra Mohan1.   

Abstract

Introduction: The development of point-of-care testing (POCT) has made clinical diagnostics available, affordable, rapid, and easy to use since the 1990s.The significance of this platform rests on its potential to empower patients to monitor their own health status more frequently, in the convenience of their home, so that diseases can be diagnosed at the earliest possible time-point. Recent advances have expanded traditional formats such as qualitative or semi-quantitative dipsticks and lateral flow immunoassays to newer platforms such as microfluidics and paper-based assays where signals can be measured quantitatively using handheld devices.Areas covered: This review discusses: (1) working principles and operating mechanisms of both existing and emerging POCT platforms, (2) urine analytes measured using POCT in comparison to the laboratory or clinical 'gold standard,' and (3) limitations of existing POCT and expectations of emerging POCT in urinalysis.Expert opinion: Currently, a variety of biological samples such as urine, saliva, serum, plasma, and other fluids can be applied to POCT for quick diagnosis, especially in resource-limited settings. Emerging platforms will increasingly empower individuals to monitor their health status through frequent urine analysis even from their homes. The impact of these emerging technologies on healthcare is likely to be transformative.

Entities:  

Keywords:  Dipstick; lateral flow assay; microfluidic paper-based analytical device; point-of-care testing; urinalysis

Mesh:

Year:  2019        PMID: 31795785      PMCID: PMC7365142          DOI: 10.1080/14737159.2020.1699063

Source DB:  PubMed          Journal:  Expert Rev Mol Diagn        ISSN: 1473-7159            Impact factor:   5.225


  114 in total

1.  Multiplex lateral-flow test strips fabricated by two-dimensional shaping.

Authors:  Erin M Fenton; Monica R Mascarenas; Gabriel P López; Scott S Sibbett
Journal:  ACS Appl Mater Interfaces       Date:  2009-01       Impact factor: 9.229

Review 2.  Point-of-care testing of proteins.

Authors:  Axel Warsinke
Journal:  Anal Bioanal Chem       Date:  2009-01-07       Impact factor: 4.142

3.  Smartphone fluorescence spectroscopy.

Authors:  Hojeong Yu; Yafang Tan; Brian T Cunningham
Journal:  Anal Chem       Date:  2014-08-13       Impact factor: 6.986

4.  Screening method to evaluate point-of-care human chorionic gonadotropin (hCG) devices for susceptibility to the hook effect by hCG β core fragment: evaluation of 11 devices.

Authors:  Robert D Nerenz; Haowei Song; Ann M Gronowski
Journal:  Clin Chem       Date:  2014-01-24       Impact factor: 8.327

Review 5.  Objective Testing: Urine and Other Drug Tests.

Authors:  Scott E Hadland; Sharon Levy
Journal:  Child Adolesc Psychiatr Clin N Am       Date:  2016-03-30

6.  A rapid urine test for early detection of kidney injury.

Authors:  Vishal S Vaidya; Glen M Ford; Sushrut S Waikar; Yizhuo Wang; Matthew B Clement; Victoria Ramirez; Warren E Glaab; Sean P Troth; Frank D Sistare; Walter C Prozialeck; Joshua R Edwards; Norma A Bobadilla; Stephen C Mefferd; Joseph V Bonventre
Journal:  Kidney Int       Date:  2009-04-22       Impact factor: 10.612

7.  Analytical performance, agreement and user-friendliness of six point-of-care testing urine analysers for urinary tract infection in general practice.

Authors:  Marjolein J C Schot; Sanne van Delft; Antoinette M J Kooijman-Buiting; Niek J de Wit; Rogier M Hopstaken
Journal:  BMJ Open       Date:  2015-05-18       Impact factor: 2.692

8.  A microfluidic paper-based electrochemical biosensor array for multiplexed detection of metabolic biomarkers.

Authors:  Chen Zhao; Martin M Thuo; Xinyu Liu
Journal:  Sci Technol Adv Mater       Date:  2013-10-18       Impact factor: 8.090

9.  Early morning urine collection to improve urinary lateral flow LAM assay sensitivity in hospitalised patients with HIV-TB co-infection.

Authors:  Phindile Gina; Philippa J Randall; Tapuwa E Muchinga; Anil Pooran; Richard Meldau; Jonny G Peter; Keertan Dheda
Journal:  BMC Infect Dis       Date:  2017-05-12       Impact factor: 3.090

10.  Concept of a point of care test to detect new oral anticoagulants in urine samples.

Authors:  Job Harenberg; Sandra Krämer; Shanshan Du; Christel Weiss; Roland Krämer
Journal:  Thromb J       Date:  2013-08-01
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  8 in total

1.  Independence of Urinary Symptoms and Urinary Dipstick Results in Voiders With Neurogenic Bladder.

Authors:  Suzanne Groah; Rochelle E Tractenberg; Jamie K Frost; Amanda Rounds; Inger Ljungberg
Journal:  Top Spinal Cord Inj Rehabil       Date:  2022-02-25

Review 2.  Design of Gold Nanoparticle Vertical Flow Assays for Point-of-Care Testing.

Authors:  Rongwei Lei; David Wang; Hufsa Arain; Chandra Mohan
Journal:  Diagnostics (Basel)       Date:  2022-04-28

Review 3.  Toilet-based continuous health monitoring using urine.

Authors:  Savas Tasoglu
Journal:  Nat Rev Urol       Date:  2022-01-21       Impact factor: 14.432

4.  Label-Free Protein Detection by Micro-Acoustic Biosensor Coupled with Electrical Field Sorting. Theoretical Study in Urine Models.

Authors:  Nikolay Mukhin; Georgii Konoplev; Aleksandr Oseev; Marc-Peter Schmidt; Oksana Stepanova; Andrey Kozyrev; Alexander Dmitriev; Soeren Hirsch
Journal:  Sensors (Basel)       Date:  2021-04-06       Impact factor: 3.576

5.  Design and Functionalization of a µPAD for the Enzymatic Determination of Nitrate in Urine.

Authors:  Francisca T S M Ferreira; Raquel B R Mesquita; António O S S Rangel
Journal:  Molecules       Date:  2021-10-21       Impact factor: 4.411

Review 6.  Plasmonic nanosensors for point-of-care biomarker detection.

Authors:  Congran Jin; Ziqian Wu; John H Molinski; Junhu Zhou; Yundong Ren; John X J Zhang
Journal:  Mater Today Bio       Date:  2022-04-16

7.  Predictive System Implementation to Improve the Accuracy of Urine Self-Diagnosis with Smartphones: Application of a Confusion Matrix-Based Learning Model through RGB Semiquantitative Analysis.

Authors:  Seon-Chil Kim; Young-Sik Cho
Journal:  Sensors (Basel)       Date:  2022-07-21       Impact factor: 3.847

8.  Metabolic Profiling from an Asymptomatic Ferret Model of SARS-CoV-2 Infection.

Authors:  David J Beale; Rohan Shah; Avinash V Karpe; Katie E Hillyer; Alexander J McAuley; Gough G Au; Glenn A Marsh; Seshadri S Vasan
Journal:  Metabolites       Date:  2021-05-19
  8 in total

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