Literature DB >> 31793391

Adenoid cystic carcinoma of trachea: long-term disease control after endoscopic surgery and radiotherapy.

Corrado Spatola1, Alessandra Tocco1, Dario Marletta2, Roberto Milazzotto1, Francesco Marletta2, Stefano Pergolizzi3, Marcello Migliore4, Antonio Basile1, Giuseppe Privitera1, Grazia Acquaviva2.   

Abstract

Aim: Adenoid cystic carcinoma is a rare tumor of head and neck region and its development in the thoracic region is even less frequent. This implies the absence of guidelines for therapeutic management and a consequent case-by-case approach. The role of radiotherapy is not yet clearly defined, but intensity-modulated radiotherapy allows for improved organ-at-risk sparing. Materials & methods: We have collected the cases of four patients treated at our institutions by the means of intensity-modulated radiotherapy, after endoscopic resection. Results & conclusion: Patients treated achieved long-term disease control of about 5 years, with a minimal acute toxicity. Longer follow-up is needed to drain conclusion on the impact of this treatment on overall survival.

Entities:  

Keywords:  IMRT; QUANTEC; adenoid cystic carcinoma; perineural invasion; postoperative radiotherapy; tracheal tumor

Mesh:

Year:  2019        PMID: 31793391     DOI: 10.2217/fon-2018-0685

Source DB:  PubMed          Journal:  Future Oncol        ISSN: 1479-6694            Impact factor:   3.404


  1 in total

1.  Primum non nocere: do we really need non-intubated thoracic surgery and robotic assisted thoracic surgery for tracheal airway resection and reconstruction?

Authors:  Marcello Migliore
Journal:  Ann Transl Med       Date:  2021-12
  1 in total

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