| Literature DB >> 31793391 |
Corrado Spatola1, Alessandra Tocco1, Dario Marletta2, Roberto Milazzotto1, Francesco Marletta2, Stefano Pergolizzi3, Marcello Migliore4, Antonio Basile1, Giuseppe Privitera1, Grazia Acquaviva2.
Abstract
Aim: Adenoid cystic carcinoma is a rare tumor of head and neck region and its development in the thoracic region is even less frequent. This implies the absence of guidelines for therapeutic management and a consequent case-by-case approach. The role of radiotherapy is not yet clearly defined, but intensity-modulated radiotherapy allows for improved organ-at-risk sparing. Materials & methods: We have collected the cases of four patients treated at our institutions by the means of intensity-modulated radiotherapy, after endoscopic resection. Results & conclusion: Patients treated achieved long-term disease control of about 5 years, with a minimal acute toxicity. Longer follow-up is needed to drain conclusion on the impact of this treatment on overall survival.Entities:
Keywords: IMRT; QUANTEC; adenoid cystic carcinoma; perineural invasion; postoperative radiotherapy; tracheal tumor
Mesh:
Year: 2019 PMID: 31793391 DOI: 10.2217/fon-2018-0685
Source DB: PubMed Journal: Future Oncol ISSN: 1479-6694 Impact factor: 3.404