Literature DB >> 31792965

Readmission after neurosurgical intervention in epilepsy: A nationwide cohort analysis.

Churl-Su Kwon1,2,3, Parul Agarwal4, Varsha Subramaniam1, Mandip Dhamoon1, Madhu Mazumdar4, Anusha Yeshokumar1, Fedor Panov3, Saadi Ghatan3, Nathalie Jetté1,2.   

Abstract

OBJECTIVE: Hospital readmissions result in increased health care costs and are associated with worse outcomes after neurosurgical intervention. Understanding factors associated with readmissions will inform future studies aimed at improving quality of care in those with epilepsy.
METHODS: Patients of all ages with epilepsy who underwent a neurosurgical intervention were identified in the 2014 Nationwide Readmissions Database, a nationally representative dataset containing data from roughly 17 million US hospital discharges. Diagnosis of epilepsy was based on International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM)-based case definitions. Neurosurgical interventions for epilepsy: resective/disconnective surgery, responsive neurostimulation/deep brain stimulation, vagus nerve stimulation, radiosurgery, and intracranial electroencephalography were identified using ICD-9-CM procedure codes. Primary outcome was all-cause 30-day readmission following discharge from the index hospitalization.
RESULTS: There were a total of 2284 index surgical admissions. Overall, 10.83% (n = 251) of patients following an index epilepsy surgery admission were readmitted within 30 days. Factors independently associated with 30-day readmission for all epilepsy surgery admissions were: Medicare insurance (P < .01), discharge disposition that was not home (P < .01), higher Elixhauser comorbidity indexes (P < .01), longer length of stay (P < .01), and adverse events of surgical and medical care during index stay (P = .04). In the multivariate model, Medicare insurance (hazard ratio [HR] 1.81 [1.29-2.53], P < .01) and length of stay (HR 1.02 [1.01-1.04], P < .01) remained significant independent predictors for 30-day readmission. The most common primary reason for readmissions was epilepsy/convulsions accounting for 22.85%. SIGNIFICANCE: Our results suggest that careful management of postoperative seizures and discharge planning after epilepsy surgery may be important to optimize outcomes and reduce the risk of readmission, particularly for patients on Medicare. Wiley Periodicals, Inc.
© 2019 International League Against Epilepsy.

Entities:  

Keywords:  epilepsy; national readmission database; population-based; surgery

Mesh:

Year:  2019        PMID: 31792965      PMCID: PMC7227389          DOI: 10.1111/epi.16401

Source DB:  PubMed          Journal:  Epilepsia        ISSN: 0013-9580            Impact factor:   5.864


  30 in total

1.  Thirty-day readmissions--truth and consequences.

Authors:  Karen E Joynt; Ashish K Jha
Journal:  N Engl J Med       Date:  2012-03-28       Impact factor: 91.245

2.  Readmission after seizure discharge in a nationally representative sample.

Authors:  Leah J Blank; James A G Crispo; Dylan P Thibault; Kathryn A Davis; Brian Litt; Allison W Willis
Journal:  Neurology       Date:  2018-12-21       Impact factor: 9.910

3.  A randomized, controlled trial of surgery for temporal-lobe epilepsy.

Authors:  S Wiebe; W T Blume; J P Girvin; M Eliasziw
Journal:  N Engl J Med       Date:  2001-08-02       Impact factor: 91.245

4.  Readmission destination and risk of mortality after major surgery: an observational cohort study.

Authors:  Benjamin S Brooke; Philip P Goodney; Larry W Kraiss; Daniel J Gottlieb; Matthew H Samore; Samuel R G Finlayson
Journal:  Lancet       Date:  2015-06-17       Impact factor: 79.321

5.  Population-based analysis of morbidity and mortality following surgery for intractable temporal lobe epilepsy in the United States.

Authors:  Shearwood McClelland; Hongfei Guo; Kolawole S Okuyemi
Journal:  Arch Neurol       Date:  2011-02-14

6.  Causes and Timing of Unplanned Early Readmission After Neurosurgery.

Authors:  Blake E S Taylor; Brett E Youngerman; Hannah Goldstein; Daniel H Kabat; Geoffrey Appelboom; William E Gold; Edward Sander Connolly
Journal:  Neurosurgery       Date:  2016-09       Impact factor: 4.654

Review 7.  Reducing hospital readmission rates: current strategies and future directions.

Authors:  Sunil Kripalani; Cecelia N Theobald; Beth Anctil; Eduard E Vasilevskis
Journal:  Annu Rev Med       Date:  2013-10-21       Impact factor: 13.739

8.  Length of Stay Beyond Medical Readiness in Neurosurgical Patients: A Prospective Analysis.

Authors:  Joseph R Linzey; Elyne N Kahn; Maksim A Shlykov; Kyle T Johnson; Katie Sullivan; Aditya S Pandey
Journal:  Neurosurgery       Date:  2019-07-01       Impact factor: 4.654

9.  Descriptive analysis of 30-day readmission after inpatient surgery discharge in the Veterans Health Administration.

Authors:  Soonhee Han; Tracy S Smith; William Gunnar
Journal:  JAMA Surg       Date:  2014-11       Impact factor: 14.766

10.  Rehospitalization and emergency department use rates before and after vagus nerve stimulation for epilepsy: use of state databases to provide longitudinal data across multiple clinical settings.

Authors:  Paul S A Kalanithi; Robert T Arrigo; Pelu Tran; Melanie Hayden Gephart; Lawrence Shuer; Robert Fisher; Maxwell Boakye
Journal:  Neuromodulation       Date:  2013-04-02
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