Literature DB >> 31789354

Effect of medication reconciliation interventions on outcomes: A systematic overview of systematic reviews.

Laura J Anderson1, Jeff L Schnipper2, Teryl K Nuckols1, Rita Shane3, Michael M Le4, Karen Robbins1, Joshua M Pevnick1.   

Abstract

PURPOSE: To evaluate and summarize published evidence from systematic reviews examining medication reconciliation.
METHODS: MEDLINE, the Cochrane Database of Systematic Reviews, and the Database of Abstracts of Reviews of Effects were searched for English-language systematic reviews published from January 2004 to March 2019. Reviewers independently extracted information and scored review quality using the Assessment of Multiple Systematic Reviews (AMSTAR) tool. For reviews with AMSTAR scores above 7, Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology was applied to assess evidence quality, with evidence summarized and conclusions compared across reviews.
RESULTS: Eleven reviews met the inclusion criteria, 5 of which used meta-analytic pooling. Most systematic reviews included primary studies of comprehensive bundled interventions that featured medication reconciliation as a central component. Reviews largely focused on transitions into and out of hospital settings. Five reviews focused exclusively on pharmacist-led interventions. Of the 5 reviews that considered all types of medication discrepancies, 3 reviews found very low-quality evidence that interventions reduced medication discrepancies. Neither of the 2 reviews that examined clinically significant medication discrepancies found any intervention effect. Of the 5 reviews that examined healthcare utilization outcomes, only 1 found any intervention effect, and that finding was based on low- to very low-quality evidence. Four reviews considered clinical outcomes, but none found any intervention effect.
CONCLUSION: An overview of systematic reviews of medication reconciliation interventions found 9 high-quality systematic reviews. A minority of those reviews' conclusions were consistent with medication reconciliation alone having a measurable impact, and such conclusions were almost all based on very low-quality evidence. © American Society of Health-System Pharmacists 2019. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  intervention; medication errors; medication reconciliation; medication review; review; systematic review

Mesh:

Year:  2019        PMID: 31789354      PMCID: PMC6885740          DOI: 10.1093/ajhp/zxz236

Source DB:  PubMed          Journal:  Am J Health Syst Pharm        ISSN: 1079-2082            Impact factor:   2.637


  28 in total

1.  Using existing systematic reviews in complex systematic reviews.

Authors:  Evelyn P Whitlock; Jennifer S Lin; Roger Chou; Paul Shekelle; Karen A Robinson
Journal:  Ann Intern Med       Date:  2008-05-20       Impact factor: 25.391

Review 2.  Medication reconciliation during the transition to and from long-term care settings: a systematic review.

Authors:  Pankdeep T Chhabra; Gail B Rattinger; Sarah K Dutcher; Melanie E Hare; Kelly L Parsons; Ilene H Zuckerman
Journal:  Res Social Adm Pharm       Date:  2011-04-21

Review 3.  Clinical pharmacists and inpatient medical care: a systematic review.

Authors:  Peter J Kaboli; Angela B Hoth; Brad J McClimon; Jeffrey L Schnipper
Journal:  Arch Intern Med       Date:  2006-05-08

Review 4.  Hospital-based medication reconciliation practices: a systematic review.

Authors:  Stephanie K Mueller; Kelly Cunningham Sponsler; Sunil Kripalani; Jeffrey L Schnipper
Journal:  Arch Intern Med       Date:  2012-07-23

5.  Unintended medication discrepancies at the time of hospital admission.

Authors:  Patricia L Cornish; Sandra R Knowles; Romina Marchesano; Vincent Tam; Steven Shadowitz; David N Juurlink; Edward E Etchells
Journal:  Arch Intern Med       Date:  2005-02-28

6.  Improving medication reconciliation in the outpatient setting.

Authors:  Prathibha Varkey; Julie Cunningham; D Susan Bisping
Journal:  Jt Comm J Qual Patient Saf       Date:  2007-05

Review 7.  Pharmacy Students and Pharmacy Technicians in Medication Reconciliation: A Review of the Current Literature.

Authors:  Heather M Champion; Julia A Loosen; Korey A Kennelty
Journal:  J Pharm Pract       Date:  2017-11-05

Review 8.  Effectiveness of pharmacist-led medication reconciliation programmes on clinical outcomes at hospital transitions: a systematic review and meta-analysis.

Authors:  Alemayehu B Mekonnen; Andrew J McLachlan; Jo-Anne E Brien
Journal:  BMJ Open       Date:  2016-02-23       Impact factor: 2.692

Review 9.  The impact of pharmacists-led medicines reconciliation on healthcare outcomes in secondary care: A systematic review and meta-analysis of randomized controlled trials.

Authors:  Ejaz Cheema; Farah Kais Alhomoud; Amnah Shams Al-Deen Kinsara; Jomanah Alsiddik; Marwah Hassan Barnawi; Morooj Abdullah Al-Muwallad; Shatha Abdulbaset Abed; Mahmoud E Elrggal; Mahmoud M A Mohamed
Journal:  PLoS One       Date:  2018-03-28       Impact factor: 3.240

Review 10.  Impact of electronic medication reconciliation interventions on medication discrepancies at hospital transitions: a systematic review and meta-analysis.

Authors:  Alemayehu B Mekonnen; Tamrat B Abebe; Andrew J McLachlan; Jo-Anne E Brien
Journal:  BMC Med Inform Decis Mak       Date:  2016-08-22       Impact factor: 2.796

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  8 in total

Review 1.  Recommendations for outcome measurement for deprescribing intervention studies.

Authors:  Elizabeth A Bayliss; Kathleen Albers; Kathy Gleason; Lisa E Pieper; Cynthia M Boyd; Noll L Campbell; Kristine E Ensrud; Shelly L Gray; Amy M Linsky; Derelie Mangin; Lillian Min; Michael W Rich; Michael A Steinman; Justin Turner; Eduard E Vasilevskis; Sascha Dublin
Journal:  J Am Geriatr Soc       Date:  2022-06-01       Impact factor: 7.538

Review 2.  Reducing medication errors for adults in hospital settings.

Authors:  Agustín Ciapponi; Simon E Fernandez Nievas; Mariana Seijo; María Belén Rodríguez; Valeria Vietto; Herney A García-Perdomo; Sacha Virgilio; Ana V Fajreldines; Josep Tost; Christopher J Rose; Ezequiel Garcia-Elorrio
Journal:  Cochrane Database Syst Rev       Date:  2021-11-25

3.  A case of pharmacist-led care team interventions to maximize rural patient quality of life.

Authors:  Megan Undeberg; Kimberly McKeirnan; David Easley; Kyle Frazier
Journal:  Explor Res Clin Soc Pharm       Date:  2021-03-10

4.  Pharmacist-led medication reconciliation at patient discharge: a tool to reduce healthcare utilization? an observational study in patients 65 years or older.

Authors:  Emma Bajeux; Lilian Alix; Lucie Cornée; Camille Barbazan; Marion Mercerolle; Jennifer Howlett; Vincent Cruveilhier; Charlotte Liné-Iehl; Bérangère Cador; Patrick Jego; Vincent Gicquel; François-Xavier Schweyer; Vanessa Marie; Stéphanie Hamonic; Jean-Michel Josselin; Dominique Somme; Benoit Hue
Journal:  BMC Geriatr       Date:  2022-07-13       Impact factor: 4.070

5.  Building Community-Engaged Multidisciplinary Partnerships to Improve Medication Management in Elderly Patients With Multiple Chronic Conditions.

Authors:  Ivy O Poon; Felicia Skelton; Lena R Bean; Dominique Guinn; Terica L Jemerson; Ngozi D Mbue; Creaque V Charles; Uche Anadu Ndefo
Journal:  J Patient Cent Res Rev       Date:  2021-04-19

6.  Tools and tactics for postdischarge medication management interventions.

Authors:  Joshua M Pevnick; Laura J Anderson; Siri Chirumamilla; Duong D Luong; Lydia E Noh; Katherine Palmer; Kallie Amer; Rita R Shane; Teryl K Nuckols; Rachel B Lesser; Jeffrey L Schnipper
Journal:  Am J Health Syst Pharm       Date:  2021-03-18       Impact factor: 2.637

7.  A mixed methods evaluation of medication reconciliation in the primary care setting.

Authors:  Michael R Gionfriddo; Vanessa Duboski; Allison Middernacht; Melissa S Kern; Jove Graham; Eric A Wright
Journal:  PLoS One       Date:  2021-12-02       Impact factor: 3.240

8.  Effect of Medication Reconciliation at Hospital Admission on 30-Day Returns to Hospital: A Randomized Clinical Trial.

Authors:  Alessandro Ceschi; Roberta Noseda; Michela Pironi; Nicole Lazzeri; Ottavia Eberhardt-Gianella; Saida Imelli; Sara Ghidossi; Stefano Bruni; Alberto Pagnamenta; Paolo Ferrari
Journal:  JAMA Netw Open       Date:  2021-09-01
  8 in total

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