Literature DB >> 31788378

Risk Factors of Incidental Parathyroidectomy and its Relationship with Hypocalcemia after Thyroidectomy: A Retrospective Study.

Erdem Karadeniz1, Mufide N Akcay1.   

Abstract

BACKGROUND: The aim of this study was to determine the incidence of incidental parathyroidectomy, the relationship between incidental parathyroidectomy and postoperative hypocalcemia, and risk factors for incidental parathyroidectomy in patients undergoing thyroid surgery.
METHODS: The study was conducted by analyzing the records of patients who underwent thyroid surgery in a tertiary university hospital between January 2012 and December 2017 retrospectively. The risk factors of postoperative hypocalcemia were determined by comparing postoperative Ca values with age, sex, preoperative Ca value, dominant nodule diameter, type of surgery, and histopathological examination of the thyroidectomy material. According to the final pathology results, the patients were divided into two groups - the ones with and without incidental parathyroidectomy. The risk factors for incidental parathyroidectomy were determined by comparing the two groups in terms of age, sex, dominant nodule diameter, type of surgery, and histopathological results (malign/benign).
RESULTS: When the risk factors of postoperative hypocalcemia were examined, female gender, age <28.5 years old, low level of preoperative mean Ca value, and total thyroidectomy were found to be critical risk factors (p<0.05). When the risk factors of incidental parathyroidectomy were examined, total thyroidectomy and thyroid malignancy were found to be important risk factors (p<0.05).
CONCLUSION: Female gender, age<28.5 years old, low level of preoperative Ca value, and total thyroidectomy were associated with postoperative hypocalcemia, but no relationship was found between incidental parathyroidectomy and postoperative hypocalcemia.
Copyright © 2019, Karadeniz et al.

Entities:  

Keywords:  hypocalcaemia; incidental; parathyroidectomy; thyroidectomy

Year:  2019        PMID: 31788378      PMCID: PMC6857829          DOI: 10.7759/cureus.5920

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  18 in total

1.  Factors related to nerve injury and hypocalcemia in thyroid gland surgery.

Authors:  M P Prim; J I de Diego; D Hardisson; R Madero; J Gavilan
Journal:  Otolaryngol Head Neck Surg       Date:  2001-01       Impact factor: 3.497

Review 2.  Parathyroid risk in total thyroidectomy for bilateral, benign, multinodular goitre: report of 351 surgical cases.

Authors:  C Page; V Strunski
Journal:  J Laryngol Otol       Date:  2006-10-23       Impact factor: 1.469

3.  Analysis of the factors that have an effect on hypocalcemia following thyroidectomy.

Authors:  Doğa Kalyoncu; Doğan Gönüllü; Mehmet Lari Gedik; Muzaffer Er; Erol Kuroğlu; Ayşenur A İğdem; Ferda Nihat Koksoy
Journal:  Ulus Cerrahi Derg       Date:  2013-12-01

Review 4.  Systematic review and meta-analysis of predictors of post-thyroidectomy hypocalcaemia.

Authors:  O Edafe; R Antakia; N Laskar; L Uttley; S P Balasubramanian
Journal:  Br J Surg       Date:  2014-01-09       Impact factor: 6.939

5.  Incidental parathyroidectomy during total thyroidectomy is not a direct cause of post-operative hypocalcaemia.

Authors:  Carolyn Chew; Ran Li; Michael K Ng; Steven T F Chan; Bill Fleming
Journal:  ANZ J Surg       Date:  2017-03-17       Impact factor: 1.872

6.  Risk factors for hypocalcemia and hypoparathyroidism following thyroidectomy: a retrospective Chinese population study.

Authors:  Ying-Hao Wang; Adheesh Bhandari; Fan Yang; Wei Zhang; Li-Jun Xue; Hai-Guang Liu; Xiao-Hua Zhang; Cheng-Ze Chen
Journal:  Cancer Manag Res       Date:  2017-11-15       Impact factor: 3.989

7.  Predictors of postoperative hypocalcemia occurring after a total thyroidectomy: results of prospective multicenter study.

Authors:  Vitalijus Eismontas; Algirdas Slepavicius; Vinsas Janusonis; Paulius Zeromskas; Virgilijus Beisa; Kestutis Strupas; Zilvinas Dambrauskas; Antanas Gulbinas; Arvydas Martinkenas
Journal:  BMC Surg       Date:  2018-08-09       Impact factor: 2.102

8.  An algorithm informed by the parathyroid hormone level reduces hypocalcemic complications of thyroidectomy.

Authors:  James E Wiseman; Matthew Mossanen; Philip H G Ituarte; Jonathan M T Bath; Michael W Yeh
Journal:  World J Surg       Date:  2010-03       Impact factor: 3.352

9.  Predictors of hypocalcemia after thyroidectomy: results from the nationwide inpatient sample.

Authors:  Randall L Baldassarre; David C Chang; Kevin T Brumund; Michael Bouvet
Journal:  ISRN Surg       Date:  2012-07-15

10.  Risk factors for incidental parathyroidectomy during thyroidectomy.

Authors:  Niklas Söderberg Campos; Lívia Petrone Cardoso; Ricardo Tirapelli Tanios; Bruna Craveiro de Oliveira; André Vicente Guimarães; Rogério Aparecido Dedivitis; Luiz Francisco Marcopito
Journal:  Braz J Otorhinolaryngol       Date:  2012-02
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  3 in total

1.  INCIDENTAL PARATHYROIDECTOMY DURING TOTAL THYROIDECTOMY AS A POSSIBLE RISK FACTOR OF HYPOCALCEMIA. EXPERIENCE OF A SINGLE CENTER AND REVIEW OF LITERATURE.

Authors:  E Spaziani; A R Di Filippo; C Di Cristofano; G Caruso; M Spaziani; S Orelli; F Fiorini; M Picchio; A De Cesare
Journal:  Acta Endocrinol (Buchar)       Date:  2021 Apr-Jun       Impact factor: 0.877

2.  A pilot feasibility study to assess vascularity and perfusion of parathyroid glands using a portable hand-held imager.

Authors:  Eugene Oh; Hun Chan Lee; Yoseph Kim; Bo Ning; Seung Yup Lee; Jaepyeong Cha; Wan Wook Kim
Journal:  Lasers Surg Med       Date:  2021-09-04       Impact factor: 4.025

3.  Risk factors for postoperative hypocalcaemia after thyroidectomy: A systematic review and meta-analysis.

Authors:  Zhimei Chen; Qiyuan Zhao; Jinlei Du; Ya Wang; Rongrong Han; Caijuan Xu; Xiaofang Chen; Min Shu
Journal:  J Int Med Res       Date:  2021-03       Impact factor: 1.671

  3 in total

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