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Literature DB >> 3178752

Use of 3-aminopropanol as an ethanolamine analogue in the study of phospholipid metabolism in Tetrahymena.

Abstract

About 50% of the ethanolamine in phosphatidylethanolamine in Tetrahymena is replaced by 3-aminopropan-1-ol when the compound is added to the growth medium. The phosphatidylpropanolamine which is formed is not converted into the corresponding phosphatidylcholine analogue by methylation. There is an increase in phosphatidylcholine formed by the phosphotransferase pathway from free [3H]choline and a decrease in the phosphatidylcholine formed by the methylation pathway from [14C]methionine. The nature of the observed phospholipid alterations suggests that the regulation of phosphatidylcholine biosynthesis in Tetrahymena may be different from that found in higher eukaryotes.

Entities: Chemical

Mesh：

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Year: 1988 PMID： 3178752 PMCID： PMC1135072 DOI： 10.1042/bj2540301

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

16 in total

1. Phosphatidylcholine biosynthesis in Tetrahymena pyriformis.

Authors: J D Smith; J H Law
Journal: Biochim Biophys Acta Date: 1970-02-10

2. The metabolism of 2-aminoethylphosphonate lipids in Tetrahymena pyriformis.

Authors: G A Thompson
Journal: Biochim Biophys Acta Date: 1969-03-04

3. Autoregulation of phospholipid N-methylation by the membrane phosphatidylethanolamine content.

Authors: B Akesson
Journal: FEBS Lett Date: 1978-08-15 Impact factor: 4.124

4. Differential selectivity of cholinephosphotransferase and ethanolaminephosphotransferase of Tetrahymena for diacylglycerol and alkylacylglycerol.

Authors: J D Smith
Journal: J Biol Chem Date: 1985-02-25 Impact factor: 5.157

5. Effect of dimethylaminoethylphosphonate on phospholipid metabolism in Tetrahymena.

Authors: J D Smith
Journal: Biochim Biophys Acta Date: 1986-10-03

6. Isolation and characterization of subcellular membranes with altered phospholipid composition from cultured fibroblasts.

Authors: F Schroeder; J F Perlmutter; M Glaser; P R Vagelos
Journal: J Biol Chem Date: 1976-08-25 Impact factor: 5.157

1. Metabolome analysis revealed increase in S-methylcysteine and phosphatidylisopropanolamine synthesis upon L-cysteine deprivation in the anaerobic protozoan parasite Entamoeba histolytica.

Authors: Afzal Husain; Dan Sato; Ghulam Jeelani; Fumika Mi-ichi; Vahab Ali; Makoto Suematsu; Tomoyoshi Soga; Tomoyoshi Nozaki
Journal: J Biol Chem Date: 2010-10-05 Impact factor: 5.157

1 in total

Use of 3-aminopropanol as an ethanolamine analogue in the study of phospholipid metabolism in Tetrahymena.

1. Phosphatidylcholine biosynthesis in Tetrahymena pyriformis.

2. The metabolism of 2-aminoethylphosphonate lipids in Tetrahymena pyriformis.

3. Autoregulation of phospholipid N-methylation by the membrane phosphatidylethanolamine content.

4. Differential selectivity of cholinephosphotransferase and ethanolaminephosphotransferase of Tetrahymena for diacylglycerol and alkylacylglycerol.

5. Effect of dimethylaminoethylphosphonate on phospholipid metabolism in Tetrahymena.

6. Isolation and characterization of subcellular membranes with altered phospholipid composition from cultured fibroblasts.

7. Manipulation of the phospholipid composition of tissue culture cells.

8. Control of phosphonic acid and phosphonolipid synthesis in Tetrahymena.

9. Effects of analogles of ethanolamine and choline on phospholipid metabolism in rat hepatocytes.

10. A quantitative determination of phosphonate phosphorus in naturally occurring aminophosphonates.

1. Metabolome analysis revealed increase in S-methylcysteine and phosphatidylisopropanolamine synthesis upon L-cysteine deprivation in the anaerobic protozoan parasite Entamoeba histolytica.