Literature DB >> 3178268

Leukoencephalopathy after prophylactic radiation for leukaemia in ataxia telangiectasia.

J A Eyre1, D Gardner-Medwin, G P Summerfield.   

Abstract

Children with ataxia telangiectasia have a high probability of developing acute lymphoblastic leukaemia, and have increased sensitivity to chemotherapy and irradiation. We report a 51/2 year old boy who had undiagnosed ataxia telangiectasia when he presented with acute lymphoblastic leukaemia. He subsequently developed a chemoradiation induced leukoencephalopathy after conventional central nervous system prophylaxis.

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Year:  1988        PMID： 3178268      PMCID： PMC1779128          DOI： 10.1136/adc.63.9.1079

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN： 0003-9888            Impact factor:   3.791


  5 in total

Review 1.  Occurrence of malignancy in immunodeficiency diseases. A literature review.

Authors:  R A Gatti; R A Good
Journal:  Cancer       Date:  1971-07       Impact factor: 6.860

2.  Ataxia telangiectasia with cancer. An indication for reduced radiotherapy and chemotherapy doses.

Authors:  R Abadir; N Hakami
Journal:  Br J Radiol       Date:  1983-05       Impact factor: 3.039

3.  The effects of radiation therapy for Hodgkin's disease in a child with ataxia telangiectasia: a clinical, biological and pathologic study.

Authors:  J Pritchard; M R Sandland; F B Breatnach; J R Pincott; R Cox; P Husband
Journal:  Cancer       Date:  1982-09-01       Impact factor: 6.860

Review 4.  Ataxia-telangiectasia: an inherited disorder of ionizing-radiation sensitivity in man. Progress in the elucidation of the underlying biochemical defect.

Authors:  P J McKinnon
Journal:  Hum Genet       Date:  1987-03       Impact factor: 4.132

5.  Ataxia-telangiectasia and acute lymphoblastic leukemia.

Authors:  S R Toledano; B J Lange
Journal:  Cancer       Date:  1980-04-01       Impact factor: 6.860
  5 in total
  5 in total

Review 1.  [Genetic predisposition and radiation sensitivity of tumors].

Authors:  W Budach
Journal:  Strahlenther Onkol       Date:  1997-09       Impact factor: 3.621

Review 2.  Clinical radiation sensitivity with DNA repair disorders: an overview.

Authors:  Julianne M Pollard; Richard A Gatti
Journal:  Int J Radiat Oncol Biol Phys       Date:  2009-08-01       Impact factor: 7.038

3.  Leukoencephalopathy after prophylactic radiation for leukaemia in ataxia telangiectasia.

Authors:  J Pritchard
Journal:  Arch Dis Child       Date:  1989-05       Impact factor: 3.791

Review 4.  Ataxia telangiectasia genes and predisposition to leukaemia, lymphoma and breast cancer.

Authors:  A M Taylor
Journal:  Br J Cancer       Date:  1992-07       Impact factor: 7.640

5.  The natural history of ataxia-telangiectasia (A-T): A systematic review.

Authors:  Emily Petley; Alexander Yule; Shaun Alexander; Shalini Ojha; William P Whitehouse
Journal:  PLoS One       Date:  2022-03-15       Impact factor: 3.752
  5 in total

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