Literature DB >> 31782645

Venous thromboembolism prophylaxis and the impact of a thrombosis service at a Canadian level 1 trauma centre

Paul T. Engels1, Heather Thomas1, Angela Coates1, Husham Bakry1, Abdulaziz Alali1, Ahmad AlGhambdi1, Ahmed Al-Jabri1, Ahmed Bugshan1.   

Abstract

Background: Venous thromboembolism (VTE) is a common and serious complication seen in patients with trauma. Guidelines recommend the routine use of pharmacologic prophylaxis; however, compliance rates vary widely. The aim of this study was to describe the clinical practice related to VTE prophylaxis in the first 24 hours after injury at our level 1 Canadian trauma centre and the impact of a thrombosis consultation service.
Methods: We performed a retrospective review of the health records of adult patients with trauma admitted between Jan. 1, 2012, and June 30, 2013. The rate of VTE was ascertained. The use of an initial prophylactic regimen, potential contraindications to prophylaxis and involvement of the thrombosis service were determined.
Results: A total of 633 patients were included, 459 men and 174 women with a mean age of 47.4 years. The mean Injury Severity Score was 15.8. The overall VTE rate was 2.8%. A total of 514 patients (81.2%) received VTE prophylaxis, mechanical in 302 (47.7%) and pharmacologic in 231 (36.5%) (19 patients received both types). The thrombosis service was involved in the care of 164 patients (25.9%). Patients seen by the thrombosis service were more likely to receive VTE prophylaxis than those not seen by the service (145 [88.4%] v. 369 [78.7%], p < 0.01).
Conclusion: Compliance with VTE prophylaxis administration was suboptimal, and opportunities for improvement exist. The involvement of a thrombosis consultation service appears to improve compliance with VTE prophylaxis, and augmented use of this service may improve clinical outcomes.
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Year:  2019        PMID: 31782645      PMCID: PMC6877389          DOI: 10.1503/cjs.012918

Source DB:  PubMed          Journal:  Can J Surg        ISSN: 0008-428X            Impact factor:   2.089


  28 in total

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Authors:  James P Byrne; Stephanie A Mason; David Gomez; Christopher Hoeft; Haris Subacius; Wei Xiong; Melanie Neal; Farhad Pirouzmand; Avery B Nathens
Journal:  J Am Coll Surg       Date:  2016-07-21       Impact factor: 6.113

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Authors:  Charles A Karcutskie; Jonathan P Meizoso; Juliet J Ray; Davis Horkan; Xiomara D Ruiz; Carl I Schulman; Nicholas Namias; Kenneth G Proctor
Journal:  JAMA Surg       Date:  2017-01-01       Impact factor: 14.766

10.  Traumatic brain injury is associated with the development of deep vein thrombosis independent of pharmacological prophylaxis.

Authors:  Donald A Reiff; Ramanath N Haricharan; Nathan M Bullington; Russell L Griffin; Gerald McGwin; Loring W Rue
Journal:  J Trauma       Date:  2009-05
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