Literature DB >> 3178143

Regional assignment of the gene coding for human sucrase-isomaltase (SI) to chromosome 3q25-26.

L F West1, M B Davis, F R Green, R H Lindenbaum, D M Swallow.   

Abstract

The gene coding for sucrase-isomaltase (SI) has recently been mapped to chromosome 3 using a cDNA probe to analyse DNA from somatic cell hybrids (Green et al. 1987). We have now used this same cDNA probe to obtain a regional localization of this gene. In situ hybridization to normal metaphase chromosomes and to chromosomes from individuals with balanced translocations suggests a regional assignment to chromosome 3q25-26.

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Year:  1988        PMID: 3178143     DOI: 10.1111/j.1469-1809.1988.tb01077.x

Source DB:  PubMed          Journal:  Ann Hum Genet        ISSN: 0003-4800            Impact factor:   1.670


  1 in total

1.  The sucrase-isomaltase structural gene (Si-s) and a regulatory gene (Si-r) are closely linked to esterase-26 (Es-26) on mouse chromosome 3.

Authors:  E H Birkenmeier; L B Rowe; L L Leeper; S J Henning
Journal:  Mamm Genome       Date:  1993-09       Impact factor: 2.957

  1 in total

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