Florian Obendorf1, Carmen Klammer1, Matthias Heinzl1, Margot Egger-Salmhofer2, Michael Resl, Benjamin Dieplinger2, Martin Clodi3. 1. Department of Internal Medicine, Saint John of God Hospital Linz, Seilerstaette 2, 4021, Linz, Austria. 2. Department of Laboratory Medicine, Saint John of God Hospital Linz, 4020, Linz, Austria. 3. Department of Internal Medicine, Saint John of God Hospital Linz, Seilerstaette 2, 4021, Linz, Austria. martin.clodi@medinterne.at.
Abstract
BACKGROUND: Seasonal influenza is responsible for excess mortality and morbidity all over the northern hemisphere. To the authors' knowledge there are no comprehensive data available about morbidity and mortality of hospitalized influenza patients in Austria. The aim of this study was to assess the intrahospital mortality of hospitalized patients with influenza in this tertiary care hospital. METHODS: During the 2017-2018 influenza season all patients presenting to the emergency department with influenza-like illness as well as hospitalized patients developing symptoms suggestive of influenza were tested with a rapid real-time PCR influenza test. In total 751 patients were tested at this tertiary care hospital and 330 showed a positive Influenza test result positive and were therefore included in the present study. The primary outcome was intrahospital mortality. RESULTS: Of the 330 positively tested patients n = 110 (33%) were type A influenza and n = 220 (67%) were type B influenza. The hospitalization rate of patients presenting to the emergency department with a positive influenza test was 59% with a mean length stay of 8.6 days in this hospital and an intrahospital mortality of 8.3% (n = 16). Pneumonia was diagnosed in 30% of hospitalized patients with influenza and antibiotics were used in 65.8% of all hospitalized patients with influenza. Patients aged 80 years and older reached an intrahospital mortality of 16.4%. CONCLUSION: The results of the present study show a high hospitalization and intrahospital mortality rate of influenza patients in a tertiary care hospital during the 2017-2018 influenza season in Austria.
BACKGROUND: Seasonal influenza is responsible for excess mortality and morbidity all over the northern hemisphere. To the authors' knowledge there are no comprehensive data available about morbidity and mortality of hospitalized influenza patients in Austria. The aim of this study was to assess the intrahospital mortality of hospitalized patients with influenza in this tertiary care hospital. METHODS: During the 2017-2018 influenza season all patients presenting to the emergency department with influenza-like illness as well as hospitalized patients developing symptoms suggestive of influenza were tested with a rapid real-time PCR influenza test. In total 751 patients were tested at this tertiary care hospital and 330 showed a positive Influenza test result positive and were therefore included in the present study. The primary outcome was intrahospital mortality. RESULTS: Of the 330 positively tested patients n = 110 (33%) were type A influenza and n = 220 (67%) were type B influenza. The hospitalization rate of patients presenting to the emergency department with a positive influenza test was 59% with a mean length stay of 8.6 days in this hospital and an intrahospital mortality of 8.3% (n = 16). Pneumonia was diagnosed in 30% of hospitalized patients with influenza and antibiotics were used in 65.8% of all hospitalized patients with influenza. Patients aged 80 years and older reached an intrahospital mortality of 16.4%. CONCLUSION: The results of the present study show a high hospitalization and intrahospital mortality rate of influenza patients in a tertiary care hospital during the 2017-2018 influenza season in Austria.
Authors: Stella G Muthuri; Sudhir Venkatesan; Puja R Myles; Jo Leonardi-Bee; Tarig S A Al Khuwaitir; Adbullah Al Mamun; Ashish P Anovadiya; Eduardo Azziz-Baumgartner; Clarisa Báez; Matteo Bassetti; Bojana Beovic; Barbara Bertisch; Isabelle Bonmarin; Robert Booy; Victor H Borja-Aburto; Heinz Burgmann; Bin Cao; Jordi Carratala; Justin T Denholm; Samuel R Dominguez; Pericles A D Duarte; Gal Dubnov-Raz; Marcela Echavarria; Sergio Fanella; Zhancheng Gao; Patrick Gérardin; Maddalena Giannella; Sophie Gubbels; Jethro Herberg; Anjarath L Higuera Iglesias; Peter H Hoger; Xiaoyun Hu; Quazi T Islam; Mirela F Jiménez; Amr Kandeel; Gerben Keijzers; Hossein Khalili; Marian Knight; Koichiro Kudo; Gabriela Kusznierz; Ilija Kuzman; Arthur M C Kwan; Idriss Lahlou Amine; Eduard Langenegger; Kamran B Lankarani; Yee-Sin Leo; Rita Linko; Pei Liu; Faris Madanat; Elga Mayo-Montero; Allison McGeer; Ziad Memish; Gokhan Metan; Auksė Mickiene; Dragan Mikić; Kristin G I Mohn; Ahmadreza Moradi; Pagbajabyn Nymadawa; Maria E Oliva; Mehpare Ozkan; Dhruv Parekh; Mical Paul; Fernando P Polack; Barbara A Rath; Alejandro H Rodríguez; Elena B Sarrouf; Anna C Seale; Bunyamin Sertogullarindan; Marilda M Siqueira; Joanna Skręt-Magierło; Frank Stephan; Ewa Talarek; Julian W Tang; Kelvin K W To; Antoni Torres; Selda H Törün; Dat Tran; Timothy M Uyeki; Annelies Van Zwol; Wendy Vaudry; Tjasa Vidmar; Renata T C Yokota; Paul Zarogoulidis; Jonathan S Nguyen-Van-Tam Journal: Lancet Respir Med Date: 2014-03-19 Impact factor: 30.700
Authors: William W Thompson; Eric Weintraub; Praveen Dhankhar; Po-Yung Cheng; Lynnette Brammer; Martin I Meltzer; Joseph S Bresee; David K Shay Journal: Influenza Other Respir Viruses Date: 2009-01 Impact factor: 4.380
Authors: Marc Rondy; Esther Kissling; Hanne-Dorthe Emborg; Alin Gherasim; Richard Pebody; Ramona Trebbien; Francisco Pozo; Amparo Larrauri; Jim McMenamin; Marta Valenciano Journal: Euro Surveill Date: 2018-03
Authors: Hilte F Geerdes-Fenge; Saskia Klein; Hans-Martin Schuldt; Micha Löbermann; Kerstin Köller; Jan Däbritz; Emil Christian Reisinger Journal: Wien Med Wochenschr Date: 2021-09-28
Authors: Amit Bahl; Steven Johnson; Gabriel Maine; Martha Hernandez Garcia; Srinivasa Nimmagadda; Lihua Qu; Nai-Wei Chen Journal: Lancet Reg Health Am Date: 2021-09-09