Literature DB >> 31776592

[Parkinson's syndromes in geriatric patients : Epidemiological, clinical and therapeutic characteristics].

K Amadori1,2, T Steiner3,4.   

Abstract

Due to their high prevalence, Parkinson's syndromes are exemplary geriatric syndromes. In addition to idiopathic Parkinson's disease, drug-induced and vascular Parkinson's syndromes are especially relevant in older age. A comprehensive anamnesis, thorough clinical neurological examination and rational additional diagnostics ensure the correct differential diagnostic classification. The multidimensional geriatric assessment is used to quantify the syndrome-specific ability impairments. The primary therapeutic objective in old age is the preservation of everyday competences. Drug treatment is centered around L‑dopa because of its favorable effect-side effect ratio. In cases of motor fluctuations, entacapone, opicapone or safinamide can be added, whereas dopamine agonists are generally unsuitable. Rivastigmine is indicated in mild to moderate Parkinson's dementia and furthermore can possibly improve gait stability. Speech therapy, as well as physical and occupational therapy, including the Parkinson's disease-specific Lee Silverman voice treatment are indispensable components of the multiprofessional treatment concept.

Entities:  

Keywords:  Epidemiology; Geriatric assessment; Geriatrics; Old age; Therapy

Mesh:

Substances:

Year:  2019        PMID: 31776592     DOI: 10.1007/s00115-019-00825-8

Source DB:  PubMed          Journal:  Nervenarzt        ISSN: 0028-2804            Impact factor:   1.214


  35 in total

1.  Lower extremity function and subsequent disability: consistency across studies, predictive models, and value of gait speed alone compared with the short physical performance battery.

Authors:  J M Guralnik; L Ferrucci; C F Pieper; S G Leveille; K S Markides; G V Ostir; S Studenski; L F Berkman; R B Wallace
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2000-04       Impact factor: 6.053

2.  The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment.

Authors:  Ziad S Nasreddine; Natalie A Phillips; Valérie Bédirian; Simon Charbonneau; Victor Whitehead; Isabelle Collin; Jeffrey L Cummings; Howard Chertkow
Journal:  J Am Geriatr Soc       Date:  2005-04       Impact factor: 5.562

3.  "Stops walking when talking" as a predictor of falls in elderly people.

Authors:  L Lundin-Olsson; L Nyberg; Y Gustafson
Journal:  Lancet       Date:  1997-03-01       Impact factor: 79.321

4.  Comprehensive Examination of Therapies for Pain in Parkinson's Disease: A Systematic Review and Meta-Analysis.

Authors:  Abdul Rehman Qureshi; Abdul Qayyum Rana; Suleiman H Malik; Syed Fayyaz H Rizvi; Shakib Akhter; Christopher Vannabouathong; Zainab Sarfraz; Ruqqiyah Rana
Journal:  Neuroepidemiology       Date:  2018-08-28       Impact factor: 3.282

5.  Rivastigmine for dementia associated with Parkinson's disease.

Authors:  Murat Emre; Dag Aarsland; Alberto Albanese; E Jane Byrne; Günther Deuschl; Peter P De Deyn; Franck Durif; Jaime Kulisevsky; Teus van Laar; Andrew Lees; Werner Poewe; Alain Robillard; Mario M Rosa; Erik Wolters; Peter Quarg; Sibel Tekin; Roger Lane
Journal:  N Engl J Med       Date:  2004-12-09       Impact factor: 91.245

6.  Prevalence of PD and other types of parkinsonism in three elderly populations of central Spain.

Authors:  Julián Benito-León; Félix Bermejo-Pareja; Javier Rodríguez; José-Antonio Molina; Rafael Gabriel; José-Manuel Morales
Journal:  Mov Disord       Date:  2003-03       Impact factor: 10.338

7.  ADS-5102 (Amantadine) Extended-Release Capsules for Levodopa-Induced Dyskinesia in Parkinson Disease (EASE LID Study): A Randomized Clinical Trial.

Authors:  Rajesh Pahwa; Caroline M Tanner; Robert A Hauser; Stuart H Isaacson; Paul A Nausieda; Daniel D Truong; Pinky Agarwal; Keith L Hull; Kelly E Lyons; Reed Johnson; Mary Jean Stempien
Journal:  JAMA Neurol       Date:  2017-08-01       Impact factor: 18.302

8.  Parkinsonism and Parkinson's disease in the elderly: a community-based survey in Brazil (the Bambuí study).

Authors:  Maira Tonidandel Barbosa; Paulo Caramelli; Débora Palma Maia; Mauro César Quintão Cunningham; Henrique Leonardo Guerra; Maria Fernanda Lima-Costa; Francisco Cardoso
Journal:  Mov Disord       Date:  2006-06       Impact factor: 10.338

9.  The effect of age of onset of PD on risk of dementia.

Authors:  D Aarsland; J T Kvaløy; K Andersen; J P Larsen; M X Tang; A Lolk; P Kragh-Sørensen; K Marder
Journal:  J Neurol       Date:  2007-02-14       Impact factor: 4.849

10.  Global, regional, and national burden of Parkinson's disease, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.

Authors: 
Journal:  Lancet Neurol       Date:  2018-10-01       Impact factor: 44.182

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