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Literature DB >> 31773111

Denosumab-Associated Peri-Implant Atypical Femur Fracture: A Case Report.

John P Dupaix¹, Mariya I Opanova¹, Lorrin S K Lee¹, Kevin Christensen¹.

Abstract

Bisphosphonate use has been associated with atypical pathologic fracture and slowed bone turnover. We present a case of a bisphosphonate-associated peri-implant atypical femur fracture following use of a recon nail for treatment of a prior bisphosphonate-associated atypical femur fracture. ©Copyright 2019 by University Health Partners of Hawai‘i (UHP Hawai‘i).

Entities: Chemical Disease Gene

Keywords: atypical femoral fractures; bisphosphonates; denosumab; peri-implant fractures

Mesh：

Substances：

Year: 2019 PMID： 31773111 PMCID： PMC6874689

Source DB: PubMed Journal: Hawaii J Health Soc Welf ISSN： 2641-5216

13 in total

1. Severely suppressed bone turnover: a potential complication of alendronate therapy.

Authors: Clarita V Odvina; Joseph E Zerwekh; D Sudhaker Rao; Naim Maalouf; Frank A Gottschalk; Charles Y C Pak
Journal: J Clin Endocrinol Metab Date: 2004-12-14 Impact factor: 5.958

2. Periprosthetic Fracture of the Femur After Long-Term Bisphosphonate Use: A Case Report.

Authors: Foster Chen; Timothy Bhattacharyya
Journal: JBJS Case Connect Date: 2012 Apr-Jun

3. Atypical Vancouver Type-C Periprosthetic Fracture Complicated by Nonunion: A Case Report.

Authors: Foster Chen; Robert Li; Ajay Lall; Sun Jin Kim; David M Hirsh; Evan M Schwechter
Journal: JBJS Case Connect Date: 2015 Apr-Jun

4. Bilateral atypical femoral fractures in a patient prescribed denosumab - a case report.

Authors: Robin N Thompson; Ciara L Armstrong; Gary Heyburn
Journal: Bone Date: 2013-12-31 Impact factor: 4.398

5. Bisphosphonate use and atypical fractures of the femoral shaft.

Authors: Jörg Schilcher; Karl Michaëlsson; Per Aspenberg
Journal: N Engl J Med Date: 2011-05-05 Impact factor: 91.245

6. Periprosthetic Atypical Femoral Fractures in Patients on Long-term Bisphosphonates: A Multicenter Retrospective Review.

Authors: Juan de Dios Robinson; Ross K Leighton; Kelly Trask; Yelena Bogdan; Paul Tornetta
Journal: J Orthop Trauma Date: 2016-04 Impact factor: 2.512

7. The effect of 8 or 5 years of denosumab treatment in postmenopausal women with osteoporosis: results from the FREEDOM Extension study.

Authors: S Papapoulos; K Lippuner; C Roux; C J F Lin; D L Kendler; E M Lewiecki; M L Brandi; E Czerwiński; E Franek; P Lakatos; C Mautalen; S Minisola; J Y Reginster; S Jensen; N S Daizadeh; A Wang; M Gavin; C Libanati; R B Wagman; H G Bone
Journal: Osteoporos Int Date: 2015-07-23 Impact factor: 4.507

2. Nepetin inhibits osteoclastogenesis by inhibiting RANKL-induced activation of NF-κB and MAPK signalling pathway, and autophagy.

Authors: Binxiang Chu; Shenao Chen; Xiaohe Zheng; Jiajing Ye; Xu Cheng; Liwei Zhang; Di Guo; Peng Wang; Dun Hong; Zhenghua Hong
Journal: J Cell Mol Med Date: 2020-11-01 Impact factor: 5.295

2 in total

Denosumab-Associated Peri-Implant Atypical Femur Fracture: A Case Report.

1. Severely suppressed bone turnover: a potential complication of alendronate therapy.

2. Periprosthetic Fracture of the Femur After Long-Term Bisphosphonate Use: A Case Report.

3. Atypical Vancouver Type-C Periprosthetic Fracture Complicated by Nonunion: A Case Report.

4. Bilateral atypical femoral fractures in a patient prescribed denosumab - a case report.

5. Bisphosphonate use and atypical fractures of the femoral shaft.

6. Periprosthetic Atypical Femoral Fractures in Patients on Long-term Bisphosphonates: A Multicenter Retrospective Review.

7. The effect of 8 or 5 years of denosumab treatment in postmenopausal women with osteoporosis: results from the FREEDOM Extension study.

8. Atypical femoral fractures bilaterally in a patient receiving denosumab.

9. Atypical fracture of the femur in a patient using denosumab--a case report.

10. Spontaneous acetabular periprosthetic fracture in a patient continuously having zoledronic acid.

1. Peri-implant fractures of the upper and lower extremities: a case series of 61 fractures.

2. Nepetin inhibits osteoclastogenesis by inhibiting RANKL-induced activation of NF-κB and MAPK signalling pathway, and autophagy.