Literature DB >> 31769450

An enzyme-assisted self-delivery system of lonidamine-peptide conjugates for selectively killing cancer cells.

Can Wu1, Jing Liu, Xuan Tang, Ziran Zhai, Keming Xu, Wenying Zhong.   

Abstract

A self-delivery system consisting of lonidamine and a self-assembling peptide was designed for the selective killing of phosphatase-overexpressing cancer cells, which was mediated by both enhanced cellular uptake of LND-peptide and enzyme-triggered intracellular fiber formation, thereby providing a generalized strategy to develop cancer-targeting systems of drug conjugates.

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Year:  2019        PMID： 31769450     DOI： 10.1039/c9cc06204a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

Review 1.  Enzymatic Noncovalent Synthesis.

Authors:  Hongjian He; Weiyi Tan; Jiaqi Guo; Meihui Yi; Adrianna N Shy; Bing Xu
Journal:  Chem Rev       Date:  2020-08-19       Impact factor: 60.622

Review 2.  From structure to application: Progress and opportunities in peptide materials development.

Authors:  Tania L Lopez-Silva; Joel P Schneider
Journal:  Curr Opin Chem Biol       Date:  2021-07-29       Impact factor: 8.972

Review 3.  The Potential of Lonidamine in Combination with Chemotherapy and Physical Therapy in Cancer Treatment.

Authors:  Yaxin Huang; Guohui Sun; Xiaodong Sun; Feifan Li; Lijiao Zhao; Rugang Zhong; Yongzhen Peng
Journal:  Cancers (Basel)       Date:  2020-11-11       Impact factor: 6.639

4.  RNA-Seq Technology Reveals the Mechanism of SDT Combined With Novel Nanobubbles Against HCC.

Authors:  Haitao Shang; Yichi Chen; Chunyue Wang; Shentao Zhang; Bolin Wu; Xitian Liang; Zhao Liu; Qiucheng Wang; Wen Cheng
Journal:  Front Mol Biosci       Date:  2022-02-07
  4 in total

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