Jin-Hee Park1, Yong Sik Jung2, Ji Young Kim2, Yujung Jo3, Sun Hyoung Bae4. 1. College of Nursing·Research Institute of Nursing Science, Ajou University, Suwon, Republic of Korea. 2. Department of Surgery, School of Medicine, Ajou University, Suwon, Republic of Korea. 3. College of Nursing, Ajou University, Suwon, Republic of Korea. 4. College of Nursing·Research Institute of Nursing Science, Ajou University, Suwon, Republic of Korea. shyoung@ajou.ac.kr.
Abstract
PURPOSE: The purpose of this study was to explore the trajectory of health-related quality of life (HRQoL) and its predictors in breast cancer patients. METHODS: A total of 126 women with newly diagnosed breast cancer provided baseline sociodemographic and medical characteristics and then completed an HRQoL questionnaire along with self-report measures of anxiety, depression, and cancer-related fatigue prior to their first cycle of chemotherapy (baseline), after chemotherapy completion, and at 6, and 12 months after chemotherapy completion. Group-based trajectory models were constructed to identify HRQoL trajectories over time. Logistic regression analysis was used to evaluate predictors of HRQoL in distinct patient groups. RESULTS: Group-based trajectory modeling classified two patient groups: participants with consistently medium overall HRQoL trajectories (41.1%) and participants with consistently low overall HRQoL trajectories (58.9%). Older age, perceived severe economic burden, and higher depression predicted consistently low overall HRQoL through 12 months after chemotherapy. CONCLUSIONS: Less than half of the total number of patients maintained a medium level of overall HRQoL after diagnosis and treatment of breast cancer, and nearly 60% continued to have lower overall HRQoL even after the treatment was complete. Older participants with more severe economic burden and higher depression experienced lower and more persistent overall HRQoL; thus, these patients should be monitored and provided supportive care as a part of survivorship care.
PURPOSE: The purpose of this study was to explore the trajectory of health-related quality of life (HRQoL) and its predictors in breast cancerpatients. METHODS: A total of 126 women with newly diagnosed breast cancer provided baseline sociodemographic and medical characteristics and then completed an HRQoL questionnaire along with self-report measures of anxiety, depression, and cancer-related fatigue prior to their first cycle of chemotherapy (baseline), after chemotherapy completion, and at 6, and 12 months after chemotherapy completion. Group-based trajectory models were constructed to identify HRQoL trajectories over time. Logistic regression analysis was used to evaluate predictors of HRQoL in distinct patient groups. RESULTS: Group-based trajectory modeling classified two patient groups: participants with consistently medium overall HRQoL trajectories (41.1%) and participants with consistently low overall HRQoL trajectories (58.9%). Older age, perceived severe economic burden, and higher depression predicted consistently low overall HRQoL through 12 months after chemotherapy. CONCLUSIONS: Less than half of the total number of patients maintained a medium level of overall HRQoL after diagnosis and treatment of breast cancer, and nearly 60% continued to have lower overall HRQoL even after the treatment was complete. Older participants with more severe economic burden and higher depression experienced lower and more persistent overall HRQoL; thus, these patients should be monitored and provided supportive care as a part of survivorship care.
Entities:
Keywords:
Adjuvant chemotherapy; Breast neoplasms; Cost of illness; Depression; Fatigue; Quality of life
Authors: Francisco García-Torres; Ángel Gómez-Solís; Sebastián Rubio García; Rosario Castillo-Mayén; Verónica González Ruíz-Ruano; Eliana Moreno; Juan Antonio Moriana; Bárbara Luque-Salas; María José Jaén-Moreno; Fátima Cuadrado-Hidalgo; Mario Gálvez-Lara; Marcin Jablonski; Beatriz Rodríguez-Alonso; Enrique Aranda Journal: Front Psychol Date: 2022-05-18
Authors: Joanne Ryan; Rosanne Freak-Poli; Aung Zaw Zaw Phyo; David A Gonzalez-Chica; Nigel P Stocks; Robyn L Woods; Jane Fisher; Thach Tran; Alice J Owen; Stephanie A Ward; Carlene J Britt Journal: Qual Life Res Date: 2021-10-22 Impact factor: 3.440