| Literature DB >> 31768718 |
Joanna Lomas Mevers1,2,3, Nathan A Call4,5,6, Kristina R Gerencser4,5,6, Mindy Scheithauer4,5,6, Sarah J Miller7, Colin Muething4,5,6, Shannon Hewett5, Courtney McCracken4, Lawrence Scahill4, Barbara O McElhanon4,6.
Abstract
Children with autism spectrum disorder (ASD) are often delayed in achieving bowel continence, resulting in negative outcomes. In this pilot trial, 20 children with ASD and encopresis were randomly assigned to multidisciplinary intervention for encopresis (MIE; n = 10) or a waitlist control group (n = 10). The MIE group was treated for constipation and received a 10-day behavioral intervention that utilized suppositories to produce predictable bowel movements that were reinforced. Caregivers were trained to implement the intervention. Results support the feasibility of clinical trials of MIE, with high enrolment, competition, attendance, and caregiver acceptability. Preliminary outcomes were positive, with six of 10 in the MIE group achieving continence by the end of treatment compared to 0 in the control group (p = 0.005).Registered at clinicaltrials.gov (https://clinicaltrials.gov); ID: NCT02383732.Entities:
Keywords: Encopresis; Multidisciplinary treatment; Pediatric gastroenterology
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Year: 2020 PMID： 31768718 DOI： 10.1007/s10803-019-04305-5
Source DB: PubMed Journal: J Autism Dev Disord ISSN： 0162-3257