Literature DB >> 31768355

Huge Gastrointestinal Stromal Tumor of the Jejunum Presenting as Bowel Obstruction: A Rare Presentation.

Tanweerul Huda1, Mahendra Pratap Singh1.   

Abstract

Gastrointestinal stromal tumors (GISTs) are mesenchymal tumors of the gastrointestinal tract arising from interstitial Cajal cells. A 54-year-old male patient without any comorbidities presented to the emergency department with complaints of abdominal distension, inability to pass flatus, and no motion for the past 2 days. Abdominal X-ray showed multiple air-fluid levels suggesting bowel obstruction. The patient was managed conservatively at first. Later, ultrasonography and contrast-enhanced computed tomography (CECT) of the abdomen were done, which revealed a mass lesion arising from the jejunum suggestive of GIST. The patient was taken up for exploratory laparotomy, and a tumor was found in the proximal jejunum around 10 cm from the duodenojejunal junction and encompassing the hepatic flexure of the transverse colon, with the omentum found adhered to the anterior surface of the lesion and distended proximal bowel loops. There was no evidence of mesenteric lymphadenopathy. The mass was resected along with the jejunal loop and the hepatic flexure of the colon, followed by end-to-end jejunojejunal anastomosis and end-to-end colocolic anastomosis. The patient's postoperative stay was uneventful. Imatinib therapy was started following histopathological confirmation and continued. The patient was followed up for 1 year postoperatively with CECT of the abdomen every 6 months, with no evidence of recurrence or any gastro-intestinal symptoms.
Copyright © 2019 by S. Karger AG, Basel.

Entities:  

Keywords:  Bowel obstruction; CD117; CD34; Gastrointestinal stromal tumor; Gastrointestinal tumor; Imatinib; Jejunal tumor; PDGFRA

Year:  2019        PMID: 31768355      PMCID: PMC6872987          DOI: 10.1159/000501744

Source DB:  PubMed          Journal:  Gastrointest Tumors        ISSN: 2296-3774


  7 in total

1.  Gastrointestinal stromal tumors and leiomyosarcomas in the colon: a clinicopathologic, immunohistochemical, and molecular genetic study of 44 cases.

Authors:  M Miettinen; M Sarlomo-Rikala; L H Sobin; J Lasota
Journal:  Am J Surg Pathol       Date:  2000-10       Impact factor: 6.394

2.  Extragastrointestinal (soft tissue) stromal tumors: an analysis of 48 cases with emphasis on histologic predictors of outcome.

Authors:  J D Reith; J R Goldblum; R H Lyles; S W Weiss
Journal:  Mod Pathol       Date:  2000-05       Impact factor: 7.842

3.  Gastrointestinal stromal tumours: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Authors:  P G Casali; N Abecassis; H T Aro; S Bauer; R Biagini; S Bielack; S Bonvalot; I Boukovinas; J V M G Bovee; T Brodowicz; J M Broto; A Buonadonna; E De Álava; A P Dei Tos; X G Del Muro; P Dileo; M Eriksson; A Fedenko; V Ferraresi; A Ferrari; S Ferrari; A M Frezza; S Gasperoni; H Gelderblom; T Gil; G Grignani; A Gronchi; R L Haas; B Hassan; P Hohenberger; R Issels; H Joensuu; R L Jones; I Judson; P Jutte; S Kaal; B Kasper; K Kopeckova; D A Krákorová; A Le Cesne; I Lugowska; O Merimsky; M Montemurro; M A Pantaleo; R Piana; P Picci; S Piperno-Neumann; A L Pousa; P Reichardt; M H Robinson; P Rutkowski; A A Safwat; P Schöffski; S Sleijfer; S Stacchiotti; K Sundby Hall; M Unk; F Van Coevorden; W T A van der Graaf; J Whelan; E Wardelmann; O Zaikova; J Y Blay
Journal:  Ann Oncol       Date:  2018-10-01       Impact factor: 32.976

4.  Gastrointestinal stromal tumors, intramural leiomyomas, and leiomyosarcomas in the rectum and anus: a clinicopathologic, immunohistochemical, and molecular genetic study of 144 cases.

Authors:  M Miettinen; M Furlong; M Sarlomo-Rikala; A Burke; L H Sobin; J Lasota
Journal:  Am J Surg Pathol       Date:  2001-09       Impact factor: 6.394

5.  Gastrointestinal stromal tumors of the stomach in children and young adults: a clinicopathologic, immunohistochemical, and molecular genetic study of 44 cases with long-term follow-up and review of the literature.

Authors:  Markku Miettinen; Jerzy Lasota; Leslie H Sobin
Journal:  Am J Surg Pathol       Date:  2005-10       Impact factor: 6.394

Review 6.  Diagnosis of gastrointestinal stromal tumors: A consensus approach.

Authors:  Christopher D M Fletcher; Jules J Berman; Christopher Corless; Fred Gorstein; Jerzy Lasota; B Jack Longley; Markku Miettinen; Timothy J O'Leary; Helen Remotti; Brian P Rubin; Barry Shmookler; Leslie H Sobin; Sharon W Weiss
Journal:  Hum Pathol       Date:  2002-05       Impact factor: 3.466

7.  A clinicopathologic and immunohistochemical study of gastrointestinal stromal tumors.

Authors:  T Ueyama; K J Guo; H Hashimoto; Y Daimaru; M Enjoji
Journal:  Cancer       Date:  1992-02-15       Impact factor: 6.860

  7 in total
  2 in total

1.  A case of jejunal GIST revealed by hematemesis: Unusual situation.

Authors:  Behzad Azimi; Mohammad Amin Shahrbaf; Majid Iranshahi; Fatemeh Parsaeian
Journal:  Int J Surg Case Rep       Date:  2022-05-03

2.  Clinicopathological characteristics and prognosis of gastrointestinal stromal tumors containing air-fluid levels.

Authors:  Tianzhu Liu; Gao Lin; Hui Peng; Lesheng Huang; Xiaosong Jiang; Hongyi Li; Kaili Cai; Jinghua Jiang; Lei Guo; Xiaohua Du; Jiahui Tang; Wanchun Zhang; Jun Chen; Yongsong Ye
Journal:  PLoS One       Date:  2021-12-17       Impact factor: 3.240

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.