Literature DB >> 31768189

The Physical and Mental Health of Middle Aged and Older Adults on the Autism Spectrum and the Impact of Intellectual Disability.

Lauren Bishop-Fitzpatrick1,2, Eric Rubenstein1.   

Abstract

BACKGROUND: People on the autism spectrum may have more physical and mental health conditions in midlife and old age compared to the general population. This study describes the physical and mental health of a unique sample of all middle aged and older Wisconsin Medicaid beneficiaries with an autism spectrum disorder diagnosis and tests differences between those with and without co-occurring intellectual disability.
METHOD: Using de-identified Medicaid claims data for 143 adults with a recorded autism spectrum disorder diagnosis aged 40-88 years with any Wisconsin Medicaid claims in 2012 through 2015, we extracted diagnoses for physical and mental health conditions from fee-for-service claims. Logistic regression analyses-controlling for sex, race, and age-compared the adjusted odds of physical and mental health conditions for those with and without intellectual disability.
RESULTS: Many physical and mental health conditions, including immune conditions (70.6%), cardiovascular disease (49.0%) and its risk factors (46.2%), sleep disorders (85.3%), gastrointestinal disorders (49.7%), neurologic conditions (55.9%), and psychiatric disorders (72.0%) were highly prevalent in our full sample. Although there were many similarities between those individuals with and without co-occurring intellectual disability, middle aged and older adults on the autism spectrum had higher prevalence of epilepsy and lower prevalence of depression and anxiety compared to those without co-occurring intellectual disability.
CONCLUSIONS: Findings suggest that people on the autism spectrum have a high prevalence of physical and mental health conditions in midlife and old age, regardless of intellectual disability status.

Entities:  

Keywords:  Medicaid; aging; disparity; health; intellectual disability; mental health

Year:  2019        PMID: 31768189      PMCID: PMC6876625          DOI: 10.1016/j.rasd.2019.01.001

Source DB:  PubMed          Journal:  Res Autism Spectr Disord


  30 in total

Review 1.  Autism spectrum disorders in older adults: toward defining a research agenda.

Authors:  Joseph Piven; Peter Rabins
Journal:  J Am Geriatr Soc       Date:  2011-11-08       Impact factor: 5.562

2.  Using machine learning to identify patterns of lifetime health problems in decedents with autism spectrum disorder.

Authors:  Lauren Bishop-Fitzpatrick; Arezoo Movaghar; Jan S Greenberg; David Page; Leann S DaWalt; Murray H Brilliant; Marsha R Mailick
Journal:  Autism Res       Date:  2018-05-07       Impact factor: 5.216

Review 3.  Minimally verbal school-aged children with autism spectrum disorder: the neglected end of the spectrum.

Authors:  Helen Tager-Flusberg; Connie Kasari
Journal:  Autism Res       Date:  2013-10-07       Impact factor: 5.216

4.  Employment outcomes of transition-aged adults with autism spectrum disorders: a state of the States report.

Authors:  Sloane Burgess; Robert E Cimera
Journal:  Am J Intellect Dev Disabil       Date:  2014-01

5.  Prevalence of autism spectrum disorders--Autism and Developmental Disabilities Monitoring Network, 14 sites, United States, 2008.

Authors: 
Journal:  MMWR Surveill Summ       Date:  2012-03-30

6.  Injury Mortality in Individuals With Autism.

Authors:  Joseph Guan; Guohua Li
Journal:  Am J Public Health       Date:  2017-03-21       Impact factor: 9.308

Review 7.  A scoping review of what is known of the physical health of adults with autism spectrum disorder.

Authors:  Andrew Cashin; Thomas Buckley; Julian N Trollor; Nicholas Lennox
Journal:  J Intellect Disabil       Date:  2016-09-13

8.  Vascular endothelial growth factor- and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesis.

Authors:  Takashi Minami; Keiko Horiuchi; Mai Miura; Md Ruhul Abid; Wakako Takabe; Noriko Noguchi; Takahide Kohro; Xijin Ge; Hiroyuki Aburatani; Takao Hamakubo; Tatsuhiko Kodama; William C Aird
Journal:  J Biol Chem       Date:  2004-09-23       Impact factor: 5.157

Review 9.  A matter of time: The necessity of temporal language in research on health conditions that present with autism spectrum disorder.

Authors:  Eric Rubenstein; Lauren Bishop-Fitzpatrick
Journal:  Autism Res       Date:  2018-09-05       Impact factor: 5.216

10.  Treatment Utilization by Adults with Autism and Co-Occurring Anxiety or Depression.

Authors:  Brenna B Maddox; Christina D Kang-Yi; Edward S Brodkin; David S Mandell
Journal:  Res Autism Spectr Disord       Date:  2018-04-11
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  21 in total

1.  Is the Autism Boom Headed for Medicaid? Patterns in the Enrollment of Autistic Adults in Wisconsin Medicaid, 2008-2018.

Authors:  Eric Rubenstein; Lauren Bishop
Journal:  Autism Res       Date:  2019-07-17       Impact factor: 5.216

2.  Deficiency of Autism-Related Gene Dock4 Leads to Impaired Spatial Memory and Hippocampal Function in Mice at Late Middle Age.

Authors:  Daji Guo; Xiaoman Yang; Ming Gao; Xiaoqing Chen; Yanping Tang; Lingling Shen; Keshen Li; Lei Shi
Journal:  Cell Mol Neurobiol       Date:  2022-05-30       Impact factor: 5.046

3.  Self-harm and Suicidality Experiences of Middle-Age and Older Adults With vs. Without High Autistic Traits.

Authors:  Rebecca A Charlton; Francesca Happé; Gavin R Stewart; Anne Corbett; Clive Ballard; Byron Creese; Dag Aarsland; Adam Hampshire
Journal:  J Autism Dev Disord       Date:  2022-05-26

Review 4.  Heterogeneity in Autism Spectrum Disorder Case-Finding Algorithms in United States Health Administrative Database Analyses.

Authors:  Scott D Grosse; Phyllis Nichols; Kwame Nyarko; Matthew Maenner; Melissa L Danielson; Lindsay Shea
Journal:  J Autism Dev Disord       Date:  2021-09-28

5.  The Association Between Obesity and Key Health or Psychosocial Outcomes Among Autistic Adults: A Systematic Review.

Authors:  Daniel G Gilmore; Anne Longo; Brittany N Hand
Journal:  J Autism Dev Disord       Date:  2021-09-15

6.  The Autism Intervention Research Network on Physical Health Autistic Researcher Review Board.

Authors:  Heather M Brown; Patrick S R Dwyer; Dena L Gassner; Steven K Kapp; Ari Ne'eman; Jacalyn G Ryan; T C Waisman; Zachary J Williams
Journal:  Pediatrics       Date:  2022-04-01       Impact factor: 9.703

7.  Fertility rates in women with intellectual and developmental disabilities in Wisconsin Medicaid.

Authors:  Eric Rubenstein; Deborah B Ehrenthal; Jenna Nobles; David C Mallinson; Lauren Bishop; Marina C Jenkins; Hsiang-Hui Kuo; Maureen S Durkin
Journal:  Disabil Health J       Date:  2022-03-24       Impact factor: 4.615

8.  Measuring Depression in Autistic Adults: Psychometric Validation of the Beck Depression Inventory-II.

Authors:  Zachary J Williams; Jonas Everaert; Katherine O Gotham
Journal:  Assessment       Date:  2020-08-29

9.  Epilepsy in adulthood: Prevalence, incidence, and associated antiepileptic drug use in autistic adults in a state Medicaid system.

Authors:  Lauren Bishop; Kiley J McLean; Eric Rubenstein
Journal:  Autism       Date:  2020-08-05

10.  Autism Characteristics and Self-Reported Health in Older Adulthood.

Authors:  Jennifer Lodi-Smith; Jonathan D Rodgers; Karl Kozlowski; Sarah Khan; Valeria Marquez Luna; Caleb J Long; James P Donnelly; Christopher Lopata; Marcus L Thomeer
Journal:  J Gerontol B Psychol Sci Soc Sci       Date:  2021-10-30       Impact factor: 4.942

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