Literature DB >> 31767726

In Vitro Susceptibility of Fusarium to Isavuconazole.

A Broutin1, J Bigot2, Y Senghor1, A Moreno-Sabater1,3, J Guitard2, C Hennequin4.   

Abstract

To evaluate the in vitro susceptibility of Fusarium to isavuconazole, 75 clinical isolates were identified using matrix-assisted laser desorption ionization-time of flight mass spectrometry and then tested with a broth microdilution method (EUCAST) and the gradient concentration strip (GCS) technique. The activity of isavuconazole overall was shown to be limited, with an MIC50 of >16 μg/ml, without significant differences between the species complexes. The categorical agreement between GCS and EUCAST was 97.4% to 100%, making the GCS as a valuable alternative.
Copyright © 2020 American Society for Microbiology.

Entities:  

Keywords:  EUCAST; Fusariumzzm321990; antifungal susceptibility testing; gradient concentration strip; isavuconazole

Mesh：

Substances：

Year:  2020        PMID： 31767726      PMCID： PMC6985727          DOI： 10.1128/AAC.01621-19

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  28 in total

1.  Matrix-assisted laser desorption ionization time-of-flight mass spectrometry for fast and accurate identification of clinically relevant Aspergillus species.

Authors:  A Alanio; J-L Beretti; B Dauphin; E Mellado; G Quesne; C Lacroix; A Amara; P Berche; X Nassif; M-E Bougnoux
Journal:  Clin Microbiol Infect       Date:  2011-05       Impact factor: 8.067

2.  Use of matrix-assisted laser desorption ionization-time of flight mass spectrometry for identification of molds of the Fusarium genus.

Authors:  David Triest; Dirk Stubbe; Koen De Cremer; Denis Piérard; Anne-Cécile Normand; Renaud Piarroux; Monique Detandt; Marijke Hendrickx
Journal:  J Clin Microbiol       Date:  2014-11-19       Impact factor: 5.948

3.  Comparative Evaluation of Etest, EUCAST, and CLSI Methods for Amphotericin B, Voriconazole, and Posaconazole against Clinically Relevant Fusarium Species.

Authors:  Abdullah M S Al-Hatmi; Anne-Cécile Normand; Stephane Ranque; Renaud Piarroux; G Sybren de Hoog; Joseph Meletiadis; Jacques F Meis
Journal:  Antimicrob Agents Chemother       Date:  2016-12-27       Impact factor: 5.191

4.  In-vitro antifungal susceptibility of clinical and environmental Fusarium spp. strains.

Authors:  I Pujol; J Guarro; J Gené; J Sala
Journal:  J Antimicrob Chemother       Date:  1997-02       Impact factor: 5.790

5.  Comparing Etest and Broth Microdilution for Antifungal Susceptibility Testing of the Most-Relevant Pathogenic Molds.

Authors:  Frédéric Lamoth; Barbara D Alexander
Journal:  J Clin Microbiol       Date:  2015-07-22       Impact factor: 5.948

6.  International Evaluation of MIC Distributions and Epidemiological Cutoff Value (ECV) Definitions for Fusarium Species Identified by Molecular Methods for the CLSI Broth Microdilution Method.

Authors:  A Espinel-Ingroff; A L Colombo; S Cordoba; P J Dufresne; J Fuller; M Ghannoum; G M Gonzalez; J Guarro; S E Kidd; J F Meis; T M S C Melhem; T Pelaez; M A Pfaller; M W Szeszs; J P Takahaschi; A M Tortorano; N P Wiederhold; J Turnidge
Journal:  Antimicrob Agents Chemother       Date:  2015-12-07       Impact factor: 5.191

Review 7.  Fusarium infections in immunocompromised patients.

Authors:  Marcio Nucci; Elias Anaissie
Journal:  Clin Microbiol Rev       Date:  2007-10       Impact factor: 26.132

Review 8.  Fusarium: Molecular Diversity and Intrinsic Drug Resistance.

Authors:  Abdullah M S Al-Hatmi; Jacques F Meis; G Sybren de Hoog
Journal:  PLoS Pathog       Date:  2016-04-07       Impact factor: 6.823

9.  Molecular Characterization and Antifungal Susceptibility of Clinical Fusarium Species From Brazil.

Authors:  Patricia F Herkert; Abdullah M S Al-Hatmi; Gabriel L de Oliveira Salvador; Marisol D Muro; Rosângela L Pinheiro; Márcio Nucci; Flávio Queiroz-Telles; G Sybren de Hoog; Jacques F Meis
Journal:  Front Microbiol       Date:  2019-04-10       Impact factor: 5.640

10.  In vitro antifungal activities of isavuconazole (BAL4815), voriconazole, and fluconazole against 1,007 isolates of zygomycete, Candida, Aspergillus, Fusarium, and Scedosporium species.

Authors:  Jesús Guinea; Teresa Peláez; Sandra Recio; Marta Torres-Narbona; Emilio Bouza
Journal:  Antimicrob Agents Chemother       Date:  2008-01-22       Impact factor: 5.938
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  1 in total

1.  CYP51 Mutations in the Fusarium solani Species Complex: First Clue to Understand the Low Susceptibility to Azoles of the Genus Fusarium.

Authors:  Pierre Vermeulen; Arnaud Gruez; Anne-Lyse Babin; Jean-Pol Frippiat; Marie Machouart; Anne Debourgogne
Journal:  J Fungi (Basel)       Date:  2022-05-20
  1 in total

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