Literature DB >> 31765991

A titanic drug resistance threat in Cryptococcus neoformans.

Hanna Zafar1, Sophie Altamirano2, Elizabeth R Ballou3, Kirsten Nielsen4.   

Abstract

Increasing resistance to frontline antifungals is a growing threat to global health. In the face of high rates of relapse for patients with cryptococcal meningitis and frequent drug resistance in clinical isolates, recent insights into Cryptococcus neoformans morphogenesis and genome plasticity take on new and urgent meaning. Here we review the state of the understanding of mechanisms of drug resistance in the context of host-relevant changes in Cryptococcus morphology and cell ploidy.
Copyright © 2019 Elsevier Ltd. All rights reserved.

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Year:  2019        PMID： 31765991      PMCID： PMC6941473          DOI： 10.1016/j.mib.2019.11.001

Source DB:  PubMed          Journal:  Curr Opin Microbiol        ISSN： 1369-5274            Impact factor:   7.934


  76 in total

1.  Large Cryptococcus neoformans isolated from brain abscess.

Authors:  G L Love; G D Boyd; D L Greer
Journal:  J Clin Microbiol       Date:  1985-12       Impact factor: 5.948

2.  Manifestations of pulmonary cryptococcosis in patients with acquired immunodeficiency syndrome.

Authors:  M L Cameron; J A Bartlett; H A Gallis; H A Waskin
Journal:  Rev Infect Dis       Date:  1991 Jan-Feb

Review 3.  Pulmonary infections mimicking cancer: a retrospective, three-year review.

Authors:  K V Rolston; S Rodriguez; N Dholakia; E Whimbey; I Raad
Journal:  Support Care Cancer       Date:  1997-03       Impact factor: 3.603

4.  Serologic evidence for Cryptococcus neoformans infection in early childhood.

Authors:  D L Goldman; H Khine; J Abadi; D J Lindenberg; R Niang; A Casadevall
Journal:  Pediatrics       Date:  2001-05       Impact factor: 7.124

5.  Characterization of a murine monoclonal antibody to Cryptococcus neoformans polysaccharide that is a candidate for human therapeutic studies.

Authors:  A Casadevall; W Cleare; M Feldmesser; A Glatman-Freedman; D L Goldman; T R Kozel; N Lendvai; J Mukherjee; L A Pirofski; J Rivera; A L Rosas; M D Scharff; P Valadon; K Westin; Z Zhong
Journal:  Antimicrob Agents Chemother       Date:  1998-06       Impact factor: 5.191

6.  Regulatory T Cell Induction and Retention in the Lungs Drives Suppression of Detrimental Type 2 Th Cells During Pulmonary Cryptococcal Infection.

Authors:  Darin L Wiesner; Kyle D Smith; Dmitri I Kotov; Judith N Nielsen; Paul R Bohjanen; Kirsten Nielsen
Journal:  J Immunol       Date:  2015-11-20       Impact factor: 5.422

7.  Estimation of Direct Healthcare Costs of Fungal Diseases in the United States.

Authors:  Kaitlin Benedict; Brendan R Jackson; Tom Chiller; Karlyn D Beer
Journal:  Clin Infect Dis       Date:  2019-05-17       Impact factor: 9.079

8.  Fluconazole-Induced Ploidy Change in Cryptococcus neoformans Results from the Uncoupling of Cell Growth and Nuclear Division.

Authors:  Sophie Altamirano; Diana Fang; Charles Simmons; Shreyas Sridhar; Peipei Wu; Kaustuv Sanyal; Lukasz Kozubowski
Journal:  mSphere       Date:  2017-06-14       Impact factor: 4.389

9.  Mismatch Repair of DNA Replication Errors Contributes to Microevolution in the Pathogenic Fungus Cryptococcus neoformans.

Authors:  Kylie J Boyce; Yina Wang; Surbhi Verma; Viplendra P S Shakya; Chaoyang Xue; Alexander Idnurm
Journal:  mBio       Date:  2017-05-30       Impact factor: 7.867

10.  Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection.

Authors:  Darin L Wiesner; Charles A Specht; Chrono K Lee; Kyle D Smith; Liliane Mukaremera; S Thera Lee; Chun G Lee; Jack A Elias; Judith N Nielsen; David R Boulware; Paul R Bohjanen; Marc K Jenkins; Stuart M Levitz; Kirsten Nielsen
Journal:  PLoS Pathog       Date:  2015-03-12       Impact factor: 6.823
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  9 in total

1.  Karyotype variation, spontaneous genome rearrangements affecting chemical insensitivity, and expression level polymorphisms in the plant pathogen Phytophthora infestans revealed using its first chromosome-scale assembly.

Authors:  Michael E H Matson; Qihua Liang; Stefano Lonardi; Howard S Judelson
Journal:  PLoS Pathog       Date:  2022-10-10       Impact factor: 7.464

2.  Three Models of Vaccination Strategies Against Cryptococcosis in Immunocompromised Hosts Using Heat-Killed Cryptococcus neoformans Δsgl1.

Authors:  Tyler G Normile; Maurizio Del Poeta
Journal:  Front Immunol       Date:  2022-05-09       Impact factor: 8.786

3.  Update on Pulmonary Cryptococcosis.

Authors:  Deborah Yamamura; Jianping Xu
Journal:  Mycopathologia       Date:  2021-06-28       Impact factor: 2.574

4.  Discovery of 5-Nitro-6-thiocyanatopyrimidines as Inhibitors of Cryptococcus neoformans and Cryptococcus gattii.

Authors:  Maureen J Donlin; Thomas R Lane; Olga Riabova; Alexander Lepioshkin; Evan Xu; Jeffrey Lin; Vadim Makarov; Sean Ekins
Journal:  ACS Med Chem Lett       Date:  2021-04-07       Impact factor: 4.345

5.  Lineages Derived from Cryptococcus neoformans Type Strain H99 Support a Link between the Capacity to Be Pleomorphic and Virulence.

Authors:  Kenya E Fernandes; James A Fraser; Dee A Carter
Journal:  mBio       Date:  2022-03-08       Impact factor: 7.786

Review 6.  Treatment strategies for cryptococcal infection: challenges, advances and future outlook.

Authors:  Kali R Iyer; Nicole M Revie; Ci Fu; Nicole Robbins; Leah E Cowen
Journal:  Nat Rev Microbiol       Date:  2021-02-08       Impact factor: 60.633

Review 7.  Cryptococcus neoformans Genotypic Diversity and Disease Outcome among HIV Patients in Africa.

Authors:  Kennedy Kassaza; Fredrickson Wasswa; Kirsten Nielsen; Joel Bazira
Journal:  J Fungi (Basel)       Date:  2022-07-15

8.  Antifungal Potential of Synthetic Peptides against Cryptococcus neoformans: Mechanism of Action Studies Reveal Synthetic Peptides Induce Membrane-Pore Formation, DNA Degradation, and Apoptosis.

Authors:  Tawanny K B Aguiar; Nilton A S Neto; Cleverson D T Freitas; Ayrles F B Silva; Leandro P Bezerra; Ellen A Malveira; Levi A C Branco; Felipe P Mesquita; Gustavo H Goldman; Luciana M R Alencar; Jose T A Oliveira; Ralph Santos-Oliveira; Pedro F N Souza
Journal:  Pharmaceutics       Date:  2022-08-12       Impact factor: 6.525

9.  mSphere of Influence: Positive Research Culture Enables Excellence and Innovation.

Authors:  Elizabeth R Ballou
Journal:  mSphere       Date:  2020-01-15       Impact factor: 4.389
  9 in total

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